DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma. | DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma. Ma RK, Tsai PY, Farghli AR, Shumway A, Kanke M, Gordan JD, Gujral TS, Vakili K, Nukaya M, Noetzli L, Ronnekleiv-Kelly S, Broom W, Barrow J, Sethupathy P., Free PMC Article | 04/24/2024 |
Expression of the primate-specific LINC00473 RNA in mouse neurons promotes excitability and CREB-regulated transcription. | Expression of the primate-specific LINC00473 RNA in mouse neurons promotes excitability and CREB-regulated transcription. Pruunsild P, Bengtson CP, Loss I, Lohrer B, Bading H., Free PMC Article | 06/12/2023 |
Long Non-coding RNA LINC00473 Promotes Breast Cancer Progression via miR-424-5p/CCNE1 Pathway. | Long Non-coding RNA LINC00473 Promotes Breast Cancer Progression via miR-424-5p/CCNE1 Pathway. Zhang C, Yang T. | 03/14/2023 |
DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling. | DNAJB1-PRKACA in HEK293T cells induces LINC00473 overexpression that depends on PKA signaling. Kim SS, Kycia I, Karski M, Ma RK, Bordt EA, Kwan J, Karki A, Winter E, Aktas RG, Wu Y, Emili A, Bauer DE, Sethupathy P, Vakili K., Free PMC Article | 02/26/2022 |
Long intergenic noncoding RNA 00473 promoting migration and invasion of trophoblastic cell line HTR-8/SVneo via regulating miR-424-5p-mediated wnt3a/beta-catenin signaling pathway. | Long intergenic noncoding RNA 00473 promoting migration and invasion of trophoblastic cell line HTR-8/SVneo via regulating miR-424-5p-mediated wnt3a/β-catenin signaling pathway. Liu C, Li H, Zhang Y, Ding H. | 09/11/2021 |
LINC00473 regulated apoptosis, proliferation and migration but could not reverse cell cycle arrest of human bone marrow mesenchymal stem cells induced by a high-dosage of dexamethasone. | LINC00473 regulated apoptosis, proliferation and migration but could not reverse cell cycle arrest of human bone marrow mesenchymal stem cells induced by a high-dosage of dexamethasone. Xu Y, Jiang Y, Wang Y, Ren Y, Zhao Z, Wang T, Li T. | 05/29/2021 |
LINC00473 functions as an oncogene and predicts poor prognosis in pancreatic cancer via the cAMP/beta-catenin axis. | LINC00473 functions as an oncogene and predicts poor prognosis in pancreatic cancer via the cAMP/β-catenin axis. Hao XF, Zhang YX, Wang XX, Sun W, Zhao J, Chen GR. | 04/3/2021 |
The long non-coding RNA LINC00473 contributes to cell proliferation via JAK-STAT3 signaling pathway by regulating miR-195-5p/SEPT2 axis in prostate cancer. | The long non-coding RNA LINC00473 contributes to cell proliferation via JAK-STAT3 signaling pathway by regulating miR-195-5p/SEPT2 axis in prostate cancer. Xing Z, Li S, Liu Z, Zhang C, Meng M, Bai Z., Free PMC Article | 12/12/2020 |
Long noncoding RNA LINC00473/miR1955p promotes glioma progression via YAP1TEAD1Hippo signaling. | Long non‑coding RNA LINC00473/miR‑195‑5p promotes glioma progression via YAP1‑TEAD1‑Hippo signaling. Wang X, Li XD, Fu Z, Zhou Y, Huang X, Jiang X., Free PMC Article | 10/24/2020 |
Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression. | Sex-Specific Role for the Long Non-coding RNA LINC00473 in Depression. Issler O, van der Zee YY, Ramakrishnan A, Wang J, Tan C, Loh YE, Purushothaman I, Walker DM, Lorsch ZS, Hamilton PJ, Peña CJ, Flaherty E, Hartley BJ, Torres-Berrío A, Parise EM, Kronman H, Duffy JE, Estill MS, Calipari ES, Labonté B, Neve RL, Tamminga CA, Brennand KJ, Dong Y, Shen L, Nestler EJ., Free PMC Article | 09/26/2020 |
Long noncoding RNA LINC00473 indicates a poor prognosis of breast cancer and accelerates tumor carcinogenesis by competing endogenous sponging miR-497. | Long noncoding RNA LINC00473 indicates a poor prognosis of breast cancer and accelerates tumor carcinogenesis by competing endogenous sponging miR-497. Bai J, Zhao WY, Li WJ, Ying ZW, Jiang DQ. | 09/12/2020 |
LINC00473/miR-374a-5p regulates esophageal squamous cell carcinoma via targeting SPIN1 to weaken the effect of radiotherapy. | LINC00473/miR-374a-5p regulates esophageal squamous cell carcinoma via targeting SPIN1 to weaken the effect of radiotherapy. Chen W, Zhang Y, Wang H, Pan T, Zhang Y, Li C. | 08/29/2020 |
LINC00473 silencing blocked the pancreatic cancer progression through enhancing miR-195-5p-targeted downregulation of PD-L1 | Long noncoding RNA LINC00473 drives the progression of pancreatic cancer via upregulating programmed death-ligand 1 by sponging microRNA-195-5p. Zhou WY, Zhang MM, Liu C, Kang Y, Wang JO, Yang XH. | 06/13/2020 |
we found that LINC00473 is also required for maintaining the expression levels of the noncoding RNACCND1 s and recruiting corepressor FUS to the CCND1 promoter. Altogether, the activation effect of LINC00473 on CCND1 is a net effect of two antagonistic regulatory pathways | LINC00473 mediates cyclin D1 expression through a balance between activation and repression signals in breast cancer cells. Shi X, Wang X. | 05/16/2020 |
LINC00473 promotes hepatocellular carcinoma progression by functioning as a ceRNA for microRNA-195 and increasing HMGA2 expression. | LINC00473 promotes hepatocellular carcinoma progression via acting as a ceRNA for microRNA-195 and increasing HMGA2 expression. Mo J, Li B, Zhou Y, Xu Y, Jiang H, Cheng X, Wu X, Zhang Y. | 04/25/2020 |
PRKAA1 was confirmed as a downstream target gene for miR-497-5p. PRKAA1 could combine with miR-497-5p, and LINC00473 knockdown or miR-497-5p overexpression downregulated the mRNA and protein expression of PRKAA1. | LINC00473/miR-497-5p Regulates Esophageal Squamous Cell Carcinoma Progression Through Targeting PRKAA1. He Z. | 04/11/2020 |
LINC00473 could act as a ceRNA of miR-637 to promote glioma progression through regulating CDK6 expression | Long non-coding RNA LINC00473 promotes glioma cells proliferation and invasion by impairing miR-637/CDK6 axis. Zhang Q, Wang G, Xu L, Yao Z, Song L. | 02/22/2020 |
BCL-2-related anti-apoptosis pathway was activated and the multidrug-resistant (MDR) genes LRP, MDR1 were up-regulated by LINC00473. Furthermore, inhibition of LINC00473 in vivo could overcome the Taxol resistance of CRC cells, could recover the expression of tumor suppressor miR-15a and chemotherapy-induced tumor regression, indicating that LINC00473 functioned as oncogene in CRC via miR-15a | LINC00473 promotes the Taxol resistance via miR-15a in colorectal cancer. Wang L, Zhang X, Sheng L, Qiu C, Luo R., Free PMC Article | 05/18/2019 |
LINC00473 acts as a promising biomarker and therapeutic target for human CRTC1-MAML2-positive mucoepidermoid carcinomas. | CRTC1-MAML2 fusion-induced lncRNA LINC00473 expression maintains the growth and survival of human mucoepidermoid carcinoma cells. Chen Z, Lin S, Li JL, Ni W, Guo R, Lu J, Kaye FJ, Wu L., Free PMC Article | 03/9/2019 |
LINC00473 is associated with the malignant status and prognosis in gastric cancer cases. | LINC00473 predicts poor prognosis and regulates cell migration and invasion in gastric cancer. Zhang W, Song Y. | 01/26/2019 |
LNC473 could recruit deubiquitinase USP9X to inhibit the ubiquitination level of survivin and then increase survivin expression. | Long noncoding RNA LNC473 inhibits the ubiquitination of survivin via association with USP9X and enhances cell proliferation and invasion in hepatocellular carcinoma cells. Chen H, Yang F, Li X, Gong ZJ, Wang LW. | 10/13/2018 |
LINC00473 transcription is suppressed by binding to ZBTB7A in chemoresistant osteosarcoma cells. | ZBTB7A Enhances Osteosarcoma Chemoresistance by Transcriptionally Repressing lncRNALINC00473-IL24 Activity. Zhang L, Wang Y, Li X, Xia X, Li N, He R, He H, Han C, Zhao W., Free PMC Article | 06/30/2018 |
Loss-of-function of LINC00473 in vivo effectively promoted the regression of Wilms tumour via miR-195/IKKalpha-mediated growth inhibition. | LINC00473 antagonizes the tumour suppressor miR-195 to mediate the pathogenesis of Wilms tumour via IKKα. Zhu S, Fu W, Zhang L, Fu K, Hu J, Jia W, Liu G., Free PMC Article | 01/27/2018 |
The authors found that cAMP-PKA pathway regulates the expression of LINC00473 through IL-11-mediated STAT3 phosphorylation. | Non-coding RNA LINC00473 mediates decidualization of human endometrial stromal cells in response to cAMP signaling. Liang XH, Deng WB, Liu YF, Liang YX, Fan ZM, Gu XW, Liu JL, Sha AG, Diao HL, Yang ZM., Free PMC Article | 01/14/2017 |
C6orf176 as a potential biomarker and/or therapeutic target in context with diseases linked to deregulated cAMP signaling. | C6orf176: a novel possible regulator of cAMP-mediated gene expression. Reitmair A, Sachs G, Im WB, Wheeler L. | 07/28/2012 |