| Impact of claudin-10 deficiency on amelogenesis: Lesson from a HELIX tooth. | Impact of claudin-10 deficiency on amelogenesis: Lesson from a HELIX tooth.
Obtel N, Le Cabec A, Nguyen TN, Giabicani E, Van Malderen SJM, Garrevoet J, Percot A, Paris C, Dean C, Hadj-Rabia S, Houillier P, Breiderhoff T, Bardet C, Coradin T, Ramirez Rozzi F, Chaussain C., Free PMC Article | 10/22/2022 |
| Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction. | Claudin-10 overexpression suppresses human clear cell renal cell carcinoma growth and metastasis by regulating ATP5O and causing mitochondrial dysfunction.
Yang W, Zhang K, Zhang Z, Zhou J, Li L, Xu Y, Qiu J, Cai L, Gong Y, Gong K., Free PMC Article | 04/23/2022 |
| A novel claudin-10 mutation with a unique mechanism in two unrelated families with HELIX syndrome. | A novel claudin-10 mutation with a unique mechanism in two unrelated families with HELIX syndrome.
Alzahrani AS, Hussein M, Alswailem M, Mouna A, Albalawi L, Moria Y, Jabbar MA, Shi Y, Günzel D, Dasouki M. | 08/7/2021 |
| Immune-related key gene CLDN10 correlates with lymph node metastasis but predicts favorable prognosis in papillary thyroid carcinoma. | Immune-related key gene CLDN10 correlates with lymph node metastasis but predicts favorable prognosis in papillary thyroid carcinoma.
Xiang Z, Zhong C, Chang A, Ling J, Zhao H, Zhou W, Zhuo X., Free PMC Article | 01/23/2021 |
| Study describes a novel claudinopathy that is based on mutations in the CLDN10 gene and characterized by an impaired function of mainly claudin-10b. Patients show a salt-losing nephropathy without hypercalciuria, and the severity of clinical manifestations may depend on site and type of mutation. [review] | A Novel Claudinopathy Based on Claudin-10 Mutations.
Milatz S., Free PMC Article | 03/28/2020 |
| The CLDN10 polymorphism of rs1325774 was significantly associated with an increased risk of breast cancer. After adjusting for age, the association remained statically significant. Furthermore, harbouring G allele in rs1325774 position was significantly associated with increased risk of breast cancer. However, no significant association among rs7333503, rs3751334, and breast cancer. | CLDN10 single nucleotide polymorphism rs1325774 alters the risk of breast cancer in south chinese women.
Liao J, Li J, Cheng H, Chen Y, Mo Z., Free PMC Article | 12/29/2018 |
| These renal-derived features recapitulate several phenotypic aspects detected in mice with kidney specific loss of both claudin-10 isoforms. Our study adds to the spectrum of phenotypes caused by tight junction proteins and demonstrates a pivotal role for claudin-10b in maintaining paracellular Na+ permeability for sweat production and kidney function. | Altered paracellular cation permeability due to a rare CLDN10B variant causes anhidrosis and kidney damage.
Klar J, Piontek J, Milatz S, Tariq M, Jameel M, Breiderhoff T, Schuster J, Fatima A, Asif M, Sher M, Mäbert K, Fromm A, Baig SM, Günzel D, Dahl N., Free PMC Article | 08/5/2017 |
| localization of Cldn3, Cldn7 and Cldn10 proteins in the different compartments of murine endometrium up to day 8.5 of pregnancy (dpc) as well as in human endometrium and first trimester decidua | Claudin-3, claudin-7, and claudin-10 show different distribution patterns during decidualization and trophoblast invasion in mouse and human.
Schumann S, Buck VU, Classen-Linke I, Wennemuth G, Grümmer R. | 09/3/2016 |
| An algorithm combining CLDN10, HMGA2, and LAMB3 transcripts was able to discriminate tumors from BTL samples (94% sensitivity and 96% specificity in validation set). | High Diagnostic Accuracy Based on CLDN10, HMGA2, and LAMB3 Transcripts in Papillary Thyroid Carcinoma.
Barros-Filho MC, Marchi FA, Pinto CA, Rogatto SR, Kowalski LP. | 08/29/2015 |
| Expression of CLDN1 and CLDN10 was lower in invasive lepidic predominant adenocarcinoma than in lung adenocarcioma in situ. Overexpression of CLDN1 and CLDN10 indicates a favorable prognosis in some patients with lung adenocarcinoma. | Expression of CLDN1 and CLDN10 in lung adenocarcinoma in situ and invasive lepidic predominant adenocarcinoma.
Zhang Z, Wang A, Sun B, Zhan Z, Chen K, Wang C., Free PMC Article | 08/22/2015 |
| Claudin 10 expression was down-regulated in gastric cancer. | The distinct expression patterns of claudin-10, -14, -17 and E-cadherin between adjacent non-neoplastic tissues and gastric cancer tissues.
Gao M, Li W, Wang H, Wang G., Free PMC Article | 07/12/2014 |
| In claudin-10b, the F66L mutant reduced cation selectivity, and the F66A mutant lost pore conductance | Conserved aromatic residue confers cation selectivity in claudin-2 and claudin-10b.
Li J, Zhuo M, Pei L, Yu AS., Free PMC Article | 10/26/2013 |
| Claudin 10/18 are most commonly expressed in lung adenocarcinomas. Female patients and non-smokers express these claudins more commonly suggesting that they may play a part in the carcinogenesis of tobacco unrelated carcinoma. | Claudins 10 and 18 are predominantly expressed in lung adenocarcinomas and in tumors of nonsmokers.
Merikallio H, Pääkkö P, Harju T, Soini Y., Free PMC Article | 03/3/2012 |
| Claudin 10 protein is highly expressed in hepatocellular carcinoma (HCC) tissue and is closely related to angiogenesis. It could be a useful marker to predict poor prognosis of HCC patients after hepatectomy. | Expression of claudin 10 protein in hepatocellular carcinoma: impact on survival.
Huang GW, Ding X, Chen SL, Zeng L. | 09/10/2011 |
| CLDN10 is a novel biomarker for detecting ovarian cancer in the chicken, a suitable animal model for investigating the effect and function of CLDN in human ovarian cancer. | Claudin 10 is a glandular epithelial marker in the chicken model as human epithelial ovarian cancer.
Seo HW, Rengaraj D, Choi JW, Ahn SE, Song YS, Song G, Han JY. | 06/4/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function. | Claudin-10 exists in six alternatively spliced isoforms that exhibit distinct localization and function.
Günzel D, Stuiver M, Kausalya PJ, Haisch L, Krug SM, Rosenthal R, Meij IC, Hunziker W, Fromm M, Müller D. | 01/21/2010 |
| These findings showed that CLDN-10 is functionally involved in hepatocellular carcinoma invasion and is a potential target for hepatocellular carcinoma therapy. | Inhibition of hepatocellular carcinoma invasion by suppression of claudin-10 in HLE cells.
Ip YC, Cheung ST, Lee YT, Ho JC, Fan ST. | 01/21/2010 |
| High Claudin-10 expression level is associated with recurrence of primary hepatocellular carcinoma | Claudin-10 expression level is associated with recurrence of primary hepatocellular carcinoma.
Cheung ST, Leung KL, Ip YC, Chen X, Fong DY, Ng IO, Fan ST, So S. | 01/21/2010 |