HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14. | HPV18 E7 inhibits LATS1 kinase and activates YAP1 by degrading PTPN14. Blakely WJ, Hatterschide J, White EA., Free PMC Article | 10/29/2024 |
LncRNA HOTAIR promotes the migration and invasion of cervical cancer through DNMT3B/LATS1/ YAP1 pS127 axis. | LncRNA HOTAIR promotes the migration and invasion of cervical cancer through DNMT3B/LATS1/ YAP1 pS127 axis. Zhang Z, Zhou X, Li J, Meng Q, Zheng P. | 10/22/2024 |
SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling. | SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling. Mei L, Qv M, Bao H, He Q, Xu Y, Zhang Q, Shi W, Ren Q, Yan Z, Xu C, Tang C, Hussain M, Zeng LH, Wu X. | 08/26/2024 |
m[6]A-induced TRIB3 regulates Hippo pathway through interacting with LATS1 to promote the progression of lung adenocarcinoma. | m(6)A-induced TRIB3 regulates Hippo pathway through interacting with LATS1 to promote the progression of lung adenocarcinoma. Wu J, Yi T, Zhuo C, Wang D, Zhang M, Hu R, Wu D, Hou G, Xing Y. | 05/31/2024 |
LATS1 Promotes B-ALL Tumorigenesis by Regulating YAP1 Phosphorylation and Subcellular Localization. | LATS1 Promotes B-ALL Tumorigenesis by Regulating YAP1 Phosphorylation and Subcellular Localization. Zhang F, Issah MA, Fu HY, Zhou HR, Liu TB, Shen JZ. | 02/27/2024 |
S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development. | S100 Calcium Binding Protein A16 Promotes Cell Proliferation by triggering LATS1 ubiquitin degradation mediated by CUL4A ligase to inhibit Hippo pathway in Glioma development. Hu Y, Zhang R, Lu S, Zhang W, Wang D, Ge Y, Jiang F, Qin X, Liu Y., Free PMC Article | 05/15/2023 |
WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein. | WWP2 drives the progression of gastric cancer by facilitating the ubiquitination and degradation of LATS1 protein. Zou J, Zhou L, Le Y, Fang Z, Zhong M, Nie F, Wei X, Zhang X, Chen Z, Cai L, Wang H, Xiong J, Fang Z, Xiang X., Free PMC Article | 02/23/2023 |
DNMT3B and TET1 mediated DNA methylation of LATS1 regulates BC progression via hippo signaling pathway. | DNMT3B and TET1 mediated DNA methylation of LATS1 regulates BC progression via hippo signaling pathway. Wu H, Jiao Y, Guo X, Wu Z, Lv Q. | 12/17/2022 |
Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas. | Inactivation of LATS1/2 drives luminal-basal plasticity to initiate basal-like mammary carcinomas. Kern JG, Tilston-Lunel AM, Federico A, Ning B, Mueller A, Peppler GB, Stampouloglou E, Cheng N, Johnson RL, Lenburg ME, Beane JE, Monti S, Varelas X., Free PMC Article | 12/10/2022 |
Identification of a novel LATS1 variant associated with familial cerebral cavernous malformations in a Chinese family. | Identification of a novel LATS1 variant associated with familial cerebral cavernous malformations in a Chinese family. Geng L, Jiang T, Zhu Y, Wang Q, Yuan W, Hu X, Zou Y, Xiao H, Liu H. | 11/5/2022 |
The clinicopathological and prognostic significances of LATS1 expression in breast cancer. | The clinicopathological and prognostic significances of LATS1 expression in breast cancer. Zheng HC, Xiang LW, Cui ZG, Xue H, E Y, Zhao MZ. | 10/15/2022 |
TRIM65 Promotes Malignant Cell Behaviors in Triple-Negative Breast Cancer by Impairing the Stability of LATS1 Protein. | TRIM65 Promotes Malignant Cell Behaviors in Triple-Negative Breast Cancer by Impairing the Stability of LATS1 Protein. Lu Y, Xiao Y, Yang J, Su H, Zhang X, Su F, Tian B, Zhao D, Ling X, Zhang T., Free PMC Article | 09/3/2022 |
Expression of LATS1 in head and neck squamous cell carcinoma and its effect on tumor cell proliferation and invasion. | Expression of LATS1 in head and neck squamous cell carcinoma and its effect on tumor cell proliferation and invasion. Wan W, Sun B, Yang S, Zhou C, Li Y. | 09/3/2022 |
LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells. | LATS kinases and SLUG regulate the transition to advanced stage in aggressive oral cancer cells. Fujibayashi E, Mukai S, Torigata K, Ando Y, Uchihashi T, Nozaki M, Tanaka S, Okada M, Kogo M, Nojima H, Yabuta N., Free PMC Article | 07/30/2022 |
Long non-coding RNA FAM66C regulates glioma growth via the miRNA/LATS1 signaling pathway. | Long non-coding RNA FAM66C regulates glioma growth via the miRNA/LATS1 signaling pathway. Xiao K, Peng G. | 06/18/2022 |
HucMSCs-exosomes containing miR-21 promoted estrogen production in ovarian granulosa cells via LATS1-mediated phosphorylation of LOXL2 and YAP. | HucMSCs-exosomes containing miR-21 promoted estrogen production in ovarian granulosa cells via LATS1-mediated phosphorylation of LOXL2 and YAP. Cai JH, Sun YT, Bao S. | 05/7/2022 |
The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1. | The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1. Han H, Nakaoka HJ, Hofmann L, Zhou JJ, Yu C, Zeng L, Nan J, Seo G, Vargas RE, Yang B, Qi R, Bardwell L, Fishman DA, Cho KWY, Huang L, Luo R, Warrior R, Wang W., Free PMC Article | 02/26/2022 |
Long non-coding RNA LOC107985656 represses the proliferation of hepatocellular carcinoma cells through activation of the tumor-suppressive Hippo pathway. | Long non-coding RNA LOC107985656 represses the proliferation of hepatocellular carcinoma cells through activation of the tumor-suppressive Hippo pathway. Zeng Y, Xu Q, Xu N., Free PMC Article | 02/19/2022 |
A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid-liquid phase separation to promote oncogenic YAP signaling. | A phosphatidic acid-binding lncRNA SNHG9 facilitates LATS1 liquid-liquid phase separation to promote oncogenic YAP signaling. Li RH, Tian T, Ge QW, He XY, Shi CY, Li JH, Zhang Z, Liu FZ, Sang LJ, Yang ZZ, Liu YZ, Xiong Y, Yan Q, Li X, Ju HQ, Liu J, Wang LJ, Shao JZ, Wang W, Zhou T, Lin A., Free PMC Article | 01/29/2022 |
Identification of the tumorsuppressive role of circular RNAFOXO3 in colorectal cancer via regulation of miR543/LATS1 axis. | Identification of the tumor‑suppressive role of circular RNA‑FOXO3 in colorectal cancer via regulation of miR‑543/LATS1 axis. Deng YY, Min YJ, Zhou K, Yang QS, Peng M, Cui ZR, Zhu XL, Liu H, Wang M, Zhang X, Liu LX., Free PMC Article | 01/8/2022 |
lncRNA TINCR attenuates the proliferation and invasion, and enhances the apoptosis of cutaneous malignant melanoma cells by regulating the miR4245p/LATS1 axis. | lncRNA TINCR attenuates the proliferation and invasion, and enhances the apoptosis of cutaneous malignant melanoma cells by regulating the miR‑424‑5p/LATS1 axis. Han X, Jia Y, Chen X, Sun C, Sun J., Free PMC Article | 01/8/2022 |
LncRNA HCG11 mediated by METTL14 inhibits the growth of lung adenocarcinoma via IGF2BP2/LATS1. | LncRNA HCG11 mediated by METTL14 inhibits the growth of lung adenocarcinoma via IGF2BP2/LATS1. Mao J, Qiu H, Guo L. | 01/1/2022 |
RASSF1A-Mediated Suppression of Estrogen Receptor Alpha (ERalpha)-Driven Breast Cancer Cell Growth Depends on the Hippo-Kinases LATS1 and 2. | RASSF1A-Mediated Suppression of Estrogen Receptor Alpha (ERα)-Driven Breast Cancer Cell Growth Depends on the Hippo-Kinases LATS1 and 2. Roßwag S, Sleeman JP, Thaler S., Free PMC Article | 12/25/2021 |
Promoter Hypermethylation of LATS1 Gene in Oral Squamous Cell Carcinoma (OSCC) among North Indian Population. | Promoter Hypermethylation of LATS1 Gene in Oral Squamous Cell Carcinoma (OSCC) among North Indian Population. Goel H, Mathur R, Syeda S, Shrivastava A, Jha AK., Free PMC Article | 11/22/2021 |
WBP2 negatively regulates the Hippo pathway by competitively binding to WWC3 with LATS1 to promote non-small cell lung cancer progression. | WBP2 negatively regulates the Hippo pathway by competitively binding to WWC3 with LATS1 to promote non-small cell lung cancer progression. Han Q, Rong X, Lin X, Zhang X, Fan C, Zhao H, Wang E., Free PMC Article | 10/16/2021 |