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    IL1RL1 interleukin 1 receptor like 1 [ Homo sapiens (human) ]

    Gene ID: 9173, updated on 2-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    ST2 and IL-33 polymorphisms and the development of childhood asthma: a prospective birth cohort study in Finnish children.

    ST2 and IL-33 polymorphisms and the development of childhood asthma: a prospective birth cohort study in Finnish children.
    Teräsjärvi JT, Toivonen L, Mertsola J, Peltola V, He Q.

    10/23/2024
    Salivary IL-33 and sST2 levels in relation to TLR2 rs111200466 polymorphism and periodontitis.

    Salivary IL-33 and sST2 levels in relation to TLR2 rs111200466 polymorphism and periodontitis.
    Yilmaz M, He Q, Demir E, Teräsjärvi J, Gürsoy UK.

    09/24/2024
    A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses.

    A type 1 immunity-restricted promoter of the IL-33 receptor gene directs antiviral T-cell responses.
    Brunner TM, Serve S, Marx AF, Fadejeva J, Saikali P, Dzamukova M, Durán-Hernández N, Kommer C, Heinrich F, Durek P, Heinz GA, Höfer T, Mashreghi MF, Kühn R, Pinschewer DD, Löhning M., Free PMC Article

    06/28/2024
    The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial-mesenchymal transition by phosphorylating beta-catenin.

    The IL-33-ST2 axis plays a vital role in endometriosis via promoting epithelial-mesenchymal transition by phosphorylating β-catenin.
    Ruan J, Tian Q, Li S, Zhou X, Sun Q, Wang Y, Xiao Y, Li M, Chang K, Yi X., Free PMC Article

    06/21/2024
    Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex.

    Oxidised IL-33 drives COPD epithelial pathogenesis via ST2-independent RAGE/EGFR signalling complex.
    Strickson S, Houslay KF, Negri VA, Ohne Y, Ottosson T, Dodd RB, Huntington CC, Baker T, Li J, Stephenson KE, O'Connor AJ, Sagawe JS, Killick H, Moore T, Rees DG, Koch S, Sanden C, Wang Y, Gubbins E, Ghaedi M, Kolbeck R, Saumyaa S, Erjefält JS, Sims GP, Humbles AA, Scott IC, Romero Ros X, Cohen ES., Free PMC Article

    10/11/2023
    IL-33-ST2 signaling promotes stemness in subtypes of myeloid leukemia cells through the Wnt and Notch pathways.

    IL-33-ST2 signaling promotes stemness in subtypes of myeloid leukemia cells through the Wnt and Notch pathways.
    Naef P, Radpour R, Jaeger-Ruckstuhl CA, Bodmer N, Baerlocher GM, Doehner H, Doehner K, Riether C, Ochsenbein AF.

    09/6/2023
    An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-epsilon4 in female patients with Alzheimer's disease.

    An IL1RL1 genetic variant lowers soluble ST2 levels and the risk effects of APOE-ε4 in female patients with Alzheimer's disease.
    Jiang Y, Zhou X, Wong HY, Ouyang L, Ip FCF, Chau VMN, Lau SF, Wu W, Wong DYK, Seo H, Fu WY, Lai NCH, Chen Y, Chen Y, Tong EPS, Alzheimer’s Disease Neuroimaging Initiative, Mok VCT, Kwok TCY, Mok KY, Shoai M, Lehallier B, Losada PM, O'Brien E, Porter T, Laws SM, Hardy J, Wyss-Coray T, Masters CL, Fu AKY, Ip NY., Free PMC Article

    05/3/2023
    Single nucleotide variants in the IL33 and IL1RL1 (ST2) genes are associated with periodontitis and with Aggregatibacter actinomycetemcomitans in the dental plaque biofilm: A putative role in understanding the host immune response in periodontitis.

    Single nucleotide variants in the IL33 and IL1RL1 (ST2) genes are associated with periodontitis and with Aggregatibacter actinomycetemcomitans in the dental plaque biofilm: A putative role in understanding the host immune response in periodontitis.
    Trindade SC, Lopes MPP, Oliveira TTMC, Silva MJ, Queiroz GA, Jesus TS, Santos EKN, Carvalho-Filho PC, Falcão MML, Miranda PM, Santos RPB, Figueiredo CA, Cruz ÁA, Seymour GJ, Gomes-Filho IS., Free PMC Article

    03/24/2023
    Association between IL1RL1 gene polymorphisms and allergic rhinitis risk in the Chinese Han population.

    Association between IL1RL1 gene polymorphisms and allergic rhinitis risk in the Chinese Han population.
    Li Z, Ren J, Zhang J, Wang X, Liu Y, Wang Q., Free PMC Article

    12/3/2022
    IL-33/ST2 axis contributes to the dermal fibrosis of systemic sclerosis via promoting fibroblasts activation.

    IL-33/ST2 axis contributes to the dermal fibrosis of systemic sclerosis via promoting fibroblasts activation.
    Wu X, Ming B, Wu T, Gao R, Hu P, Tang J, Zhong J, Zheng F, Dong L.

    10/1/2022
    IL-33/ST2 Activation Is involved in Ro60-Regulated Photosensitivity in Cutaneous Lupus Erythematosus.

    IL-33/ST2 Activation Is involved in Ro60-Regulated Photosensitivity in Cutaneous Lupus Erythematosus.
    Song Y, Wei F, Liu Y, Han F, Ma L, Zhuang Y, Pan C, Jia Z, Gong A., Free PMC Article

    08/6/2022
    Correlation of serum ST2 levels with severity of diastolic dysfunction on echocardiography and findings on cardiac MRI in patients with heart failure with preserved ejection fraction.

    Correlation of serum ST2 levels with severity of diastolic dysfunction on echocardiography and findings on cardiac MRI in patients with heart failure with preserved ejection fraction.
    Agrawal V, Hardas S, Gujar H, Phalgune DS., Free PMC Article

    07/2/2022
    IL1RL1 single nucleotide polymorphisms are associated with asthma in the Iranian population.

    IL1RL1 single nucleotide polymorphisms are associated with asthma in the Iranian population.
    Ranjbar M, Matloubi M, Sadegh S, Fallahpour M, Janani L, Assarehzadegan MA.

    06/18/2022
    Role of altered IL-33/ST2 immune axis in the immunobiology of Guillain-Barre syndrome.

    Role of altered IL-33/ST2 immune axis in the immunobiology of Guillain-Barré syndrome.
    Sharma PP, Seshagiri DV, Nagappa M, Mullapudi T, Sreenivas N, Dey S, Shivaram S, Wahatule R, Kumawat V, Sreekumaran Nair BV, Kamath S, Sinha S, Taly AB, Debnath M.

    06/18/2022
    Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma.

    Increased expression of IL1-RL1 is associated with type 2 and type 1 immune pathways in asthma.
    Xu C, Du L, Chen F, Tang K, Tang L, Shi J, Xiao L, Zeng Z, Liang Y, Guo Y., Free PMC Article

    05/28/2022
    Suppression of tumorigenicity-2 (ST2) is a promising biomarker in heart transplantation.

    Suppression of tumorigenicity-2 (ST2) is a promising biomarker in heart transplantation.
    Galeone A, Salem JE, Lebreton G, Coutance G, Nguyen L, Hulot JS, Atassi F, Bega M, Leprince P, Varnous S.

    05/21/2022
    Variants in proinflammatory genes IL1RL1, IL1B and IRF4 are associated with overweight in a pediatric Brazilian population.

    Variants in proinflammatory genes IL1RL1, IL1B and IRF4 are associated with overweight in a pediatric Brazilian population.
    Melo APC, Teixeira HMP, Coelho RS, De Jesus TDS, Queiroz GA, Silva HDS, De Almeida YCF, Alcantara-Neves NM, De Matos SMA, D'innocenzo S, Silva RCR, Lima Barreto M, Costa RDS, Pinto LC, Figueiredo CA.

    05/14/2022
    The function of IL-33/ST2 signaling axis in treg cells activating fibrosis in IgG4-related disease.

    The function of IL-33/ST2 signaling axis in treg cells activating fibrosis in IgG4-related disease.
    Wu Y, Liu J, Yu T, Zhang J, Jin X, Ye Y, Zhang R, Wang L.

    04/23/2022
    Soluble ST2 Receptor: Biomarker of Left Ventricular Impairment and Functional Status in Patients with Inflammatory Cardiomyopathy.

    Soluble ST2 Receptor: Biomarker of Left Ventricular Impairment and Functional Status in Patients with Inflammatory Cardiomyopathy.
    Obradovic DM, Büttner P, Rommel KP, Blazek S, Loncar G, von Haehling S, von Roeder M, Lücke C, Gutberlet M, Thiele H, Lurz P, Besler C., Free PMC Article

    04/16/2022
    Genetic variants in IL33 and IL1RL1 genes confer susceptibility to HBV-related liver cirrhosis in Chinese Han population.

    Genetic variants in IL33 and IL1RL1 genes confer susceptibility to HBV-related liver cirrhosis in Chinese Han population.
    Ma N, Xu M, Dong Y, Yu F, Zhang X, Gao X, Meng Y, Gao P, Zhou J, Yuan M, Mi Y, Qi S, Li L, Liu D, Liu W, Yang L.

    03/19/2022
    Interleukin 1 receptor-like 1 rs13408661/13431828 polymorphism is associated with persistent post-bronchiolitis asthma at school age.

    Interleukin 1 receptor-like 1 rs13408661/13431828 polymorphism is associated with persistent post-bronchiolitis asthma at school age.
    Riikonen R, Teräsjärvi J, Lauhkonen E, Nuolivirta K, He Q, Korppi M., Free PMC Article

    03/12/2022
    IL-1RL1a serum levels and IL1RL1 SNPs in the prediction of food allergy.

    IL-1RL1a serum levels and IL1RL1 SNPs in the prediction of food allergy.
    Ketelaar ME, Westerlaken-van Ginkel CD, Nawijn MC, Ej Dubois A, Koppelman GH., Free PMC Article

    01/15/2022
    Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling.

    Gut Microbial Metabolite Pravastatin Attenuates Intestinal Ischemia/Reperfusion Injury Through Promoting IL-13 Release From Type II Innate Lymphoid Cells via IL-33/ST2 Signaling.
    Deng F, Hu JJ, Yang X, Sun QS, Lin ZB, Zhao BC, Yao ZW, Luo SD, Chen ZL, Liu Y, Yan ZZ, Li C, Liu WF, Liu KX., Free PMC Article

    12/25/2021
    Role of the IL-33/ST2 axis in cardiovascular disease: A systematic review and meta-analysis.

    Role of the IL-33/ST2 axis in cardiovascular disease: A systematic review and meta-analysis.
    Sun Y, Pavey H, Wilkinson I, Fisk M., Free PMC Article

    12/25/2021
    Role of the IL33 and IL1RL1 pathway in the pathogenesis of Immunoglobulin A vasculitis.

    Role of the IL33 and IL1RL1 pathway in the pathogenesis of Immunoglobulin A vasculitis.
    Prieto-Peña D, Remuzgo-Martínez S, Genre F, Pulito-Cueto V, Atienza-Mateo B, Llorca J, Sevilla-Pérez B, Ortego-Centeno N, Marquez A, Lera-Gómez L, Leonardo MT, Peñalba A, Narváez J, Martín-Penagos L, Rodrigo E, Miranda-Filloy JA, Caminal-Montero L, Collado P, Sánchez Pérez J, de Argila D, Rubio E, León Luque M, Blanco-Madrigal JM, Galíndez-Agirregoikoa E, Gualillo O, Martín J, Castañeda S, Blanco R, González-Gay MA, López-Mejías R., Free PMC Article

    11/13/2021
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