| CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis. | CircDHRS3 inhibits prostate cancer cell proliferation and metastasis through the circDHRS3/miR-421/MEIS2 axis.
Dai X, Chen X, Chen W, Ou Y, Chen Y, Wu S, Zhou Q, Yang C, Zhang L, Jiang H., Free PMC Article | 02/28/2023 |
| Inhibition of retinoic acid receptor alpha phosphorylation represses the progression of triple-negative breast cancer via transactivating miR-3074-5p to target DHRS3. | Inhibition of retinoic acid receptor α phosphorylation represses the progression of triple-negative breast cancer via transactivating miR-3074-5p to target DHRS3.
Lou S, Gao H, Hong H, Zhu Z, Zhao H., Free PMC Article | 11/27/2021 |
| Yap targets Dhrs3, to reduce retinoic acid synthesis and inhibit cardiac fibroblast differentiation during development. | Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development.
Xiao Y, Hill MC, Zhang M, Martin TJ, Morikawa Y, Wang S, Moise AR, Wythe JD, Martin JF., Free PMC Article | 05/4/2018 |
| Mouse Dhrs3 plays critical roles in the development of the heart by controlling the formation of retinoic acid. | Retinoic acid signaling promotes the cytoskeletal rearrangement of embryonic epicardial cells.
Wang S, Yu J, Jones JW, Pierzchalski K, Kane MA, Trainor PA, Xavier-Neto J, Moise AR., Free PMC Article | 03/5/2018 |
| The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during mouse embryonic development | The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development.
Billings SE, Pierzchalski K, Butler Tjaden NE, Pang XY, Trainor PA, Kane MA, Moise AR., Free PMC Article | 03/5/2018 |
| we proposed that four newly identified peripheral blood mononuclear cells-derived genes( DHRS3, TTC38, SAP30BP and LPIN2 )could be integrated with previously reported rheumatoid arthritis (RA)-associated genes to monitor and/or diagnose RA. | New genes associated with rheumatoid arthritis identified by gene expression profiling.
Wang H, Guo J, Jiang J, Wu W, Chang X, Zhou H, Li Z, Zhao J. | 12/16/2017 |
| the bifunctional nature of retinoid oxidoreductase complex provides the RA-based signaling system with robustness by safeguarding appropriate RA concentration despite naturally occurring fluctuations in RDH10 and DHRS3. | The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all-trans-retinoic acid homeostasis.
Belyaeva OV, Adams MK, Wu L, Kedishvili NY., Free PMC Article | 06/3/2017 |
| Data indicate that retinaldehyde reductase (DHRS3) requires retinol dehydrogenase 10 (RDH10) for full enzymatic activity and, in turn, activates RDH10. | The retinaldehyde reductase activity of DHRS3 is reciprocally activated by retinol dehydrogenase 10 to control retinoid homeostasis.
Adams MK, Belyaeva OV, Wu L, Kedishvili NY., Free PMC Article | 11/8/2014 |
| p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation. | p53-Inducible DHRS3 is an endoplasmic reticulum protein associated with lipid droplet accumulation.
Deisenroth C, Itahana Y, Tollini L, Jin A, Zhang Y., Free PMC Article | 05/12/2012 |
| The retSDR1 is identified as novel transcriptional target of the p53 family and not transactivated by EEC syndrome-specific mutations of TAp63gamma. | The retinal dehydrogenase/reductase retSDR1/DHRS3 gene is activated by p53 and p63 but not by mutants derived from tumors or EEC/ADULT malformation syndromes.
Kirschner RD, Rother K, Müller GA, Engeland K. | 09/10/2011 |
| Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
| CST6, CXCL14, DHRS3, and SPP1 are regulated by BRAF signaling and may play a role in papillary thyroid carcinoma pathogenesis | Gene expression profiling of papillary thyroid carcinoma identifies transcripts correlated with BRAF mutational status and lymph node metastasis.
Oler G, Camacho CP, Hojaij FC, Michaluart P Jr, Riggins GJ, Cerutti JM., Free PMC Article | 01/21/2010 |