| The G Protein-Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell Migration. | The G Protein-Coupled Receptor GPR56 Is an Inhibitory Checkpoint for NK Cell Migration.
Palacios D, Majhi RK, Szabo EK, Clement D, Lachota M, Netskar H, Penna L, Krokeide SZ, Vincenti M, Kveberg L, Malmberg KJ., Free PMC Article | 10/30/2024 |
| Differential GPR56 Expression in T Cell Subpopulations for Early-Stage Lung Adenocarcinoma Patient Identification. | Differential GPR56 Expression in T Cell Subpopulations for Early-Stage Lung Adenocarcinoma Patient Identification.
Ren J, Zhu Y, Nie Y, Zheng M, Hasimu A, Zhao M, Zhao Y, Ma X, Yuan Z, Li Q, Bahabayi A, Zhang Z, Zeng X, Liu C. | 08/23/2024 |
| Expression of GPR56 reflects a hypoactivated state of circulating B cells and is downregulated in B cell subsets in patients with early-stage lung adenocarcinoma. | Expression of GPR56 reflects a hypoactivated state of circulating B cells and is downregulated in B cell subsets in patients with early-stage lung adenocarcinoma.
Bahabayi A, Guan Z, Zheng M, Yu H, Hasimu A, Nie Y, Zhao M, Zhu Y, Ren J, Zhao Y, Ma X, Li Q, Zhang Z, Zeng X, Liu C. | 08/21/2024 |
| GPR56 Promotes Diabetic Kidney Disease Through eNOS Regulation in Glomerular Endothelial Cells. | GPR56 Promotes Diabetic Kidney Disease Through eNOS Regulation in Glomerular Endothelial Cells.
Wu J, Wang Z, Cai M, Wang X, Lo B, Li Q, He JC, Lee K, Fu J., Free PMC Article | 02/1/2024 |
| Downstream signalling of the disease-associated mutations on GPR56/ADGRG1. | Downstream signalling of the disease-associated mutations on GPR56/ADGRG1.
Cevheroğlu O, Demir N, Kesici MS, Özçubukçu S, Son ÇD. | 10/5/2023 |
| Re-routing GPR56 signalling using Galpha12/13 G protein chimeras. | Re-routing GPR56 signalling using Gα(12/13) G protein chimeras.
Faas F, Nørskov A, Holst PJ, Andersson AM, Qvortrup K, Mathiasen S, Rosenkilde MM. | 10/5/2023 |
| Cobblestone-like brain malformation with a new bi-allelic ADGRG1 (GPR-56) mutation: Fetal imaging-pathology correlation. | Cobblestone-like brain malformation with a new bi-allelic ADGRG1 (GPR-56) mutation: Fetal imaging-pathology correlation.
Izzo G, Toto V, Faiola S, Cattaneo E, Cavallari U, Passarini A, Gladin CR, Scelsa B, Parazzini C, Righini A. | 07/20/2023 |
| Ablation of GPR56 Causes beta-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane. | Ablation of GPR56 Causes β-Cell Dysfunction by ATP Loss through Mistargeting of Mitochondrial VDAC1 to the Plasma Membrane.
Mohammad Al-Amily I, Sjögren M, Duner P, Tariq M, Wollheim CB, Salehi A., Free PMC Article | 04/5/2023 |
| Role of GPR56 in Platelet Activation and Arterial Thrombosis. | Role of GPR56 in Platelet Activation and Arterial Thrombosis.
Liu D, Zhang P, Zhang K, Bi C, Li L, Xu Y, Zhang T, Zhang J. | 03/6/2023 |
| Single cell sequencing identifies clonally expanded synovial CD4(+) TPH cells expressing GPR56 in rheumatoid arthritis. | Single cell sequencing identifies clonally expanded synovial CD4(+) T(PH) cells expressing GPR56 in rheumatoid arthritis.
Argyriou A, Wadsworth MH 2nd, Lendvai A, Christensen SM, Hensvold AH, Gerstner C, van Vollenhoven A, Kravarik K, Winkler A, Malmström V, Chemin K., Free PMC Article | 07/23/2022 |
| SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic beta-cells. | SNAP-tag-enabled super-resolution imaging reveals constitutive and agonist-dependent trafficking of GPR56 in pancreatic β-cells.
Olaniru OE, Cheng J, Ast J, Arvaniti A, Atanes P, Huang GC, King AJF, Jones PM, Broichhagen J, Hodson DJ, Persaud SJ., Free PMC Article | 03/26/2022 |
| Adhesion GPCR GPR56 Expression Profiling in Human Tissues. | Adhesion GPCR GPR56 Expression Profiling in Human Tissues.
Kaiser F, Morawski M, Krohn K, Rayes N, Hsiao CC, Quaas M, Aust G., Free PMC Article | 01/22/2022 |
| The role of GPR56/ADGRG1 in health and disease. | The role of GPR56/ADGRG1 in health and disease.
Singh AK, Lin HH., Free PMC Article | 01/1/2022 |
| ADGRG1 enriches for functional human hematopoietic stem cells following ex vivo expansion-induced mitochondrial oxidative stress. | ADGRG1 enriches for functional human hematopoietic stem cells following ex vivo expansion-induced mitochondrial oxidative stress.
Chen Y, Fang S, Ding Q, Jiang R, He J, Wang Q, Jin Y, Huang X, Liu S, Capitano ML, Trinh T, Teng Y, Meng Q, Wan J, Broxmeyer HE, Guo B., Free PMC Article | 12/4/2021 |
| GPR56: An adhesion GPCR involved in brain development, neurological disorders and cancer. | GPR56: An adhesion GPCR involved in brain development, neurological disorders and cancer.
Ganesh RA, Venkataraman K, Sirdeshmukh R. | 10/9/2021 |
| Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion. | Anti-GPR56 monoclonal antibody potentiates GPR56-mediated Src-Fak signaling to modulate cell adhesion.
Chatterjee T, Zhang S, Posey TA, Jacob J, Wu L, Yu W, Francisco LE, Liu QJ, Carmon KS., Free PMC Article | 08/28/2021 |
| In Silico Approach in Designing a Novel Multi-Epitope Vaccine Candidate against Non-Small Cell Lung Cancer with Overexpressed G Protein-Coupled Receptor 56. | In Silico Approach in Designing a Novel Multi-Epitope Vaccine Candidate against Non-Small Cell Lung Cancer with Overexpressed G Protein-Coupled Receptor 56.
Herrera LRM., Free PMC Article | 06/5/2021 |
| The polymicrogyria-associated GPR56 promoter preferentially drives gene expression in developing GABAergic neurons in common marmosets. | The polymicrogyria-associated GPR56 promoter preferentially drives gene expression in developing GABAergic neurons in common marmosets.
Murayama AY, Kuwako KI, Okahara J, Bae BI, Okuno M, Mashiko H, Shimogori T, Walsh CA, Sasaki E, Okano H., Free PMC Article | 05/8/2021 |
| High expression of the stem cell marker <i>GPR56</i> at diagnosis identifies acute myeloid leukemia patients at higher relapse risk after allogeneic stem cell transplantation in context with the CD34+/CD38- population. | High expression of the stem cell marker GPR56 at diagnosis identifies acute myeloid leukemia patients at higher relapse risk after allogeneic stem cell transplantation in context with the CD34+/CD38- population.
Jentzsch M, Bill M, Grimm J, Schulz J, Schuhmann L, Brauer D, Goldmann K, Wilke F, Franke GN, Behre G, Pönisch W, Vucinic V, Niederwieser D, Platzbecker U, Schwind S., Free PMC Article | 05/1/2021 |
| Specific and direct modulation of the interaction between adhesion GPCR GPR56/ADGRG1 and tissue transglutaminase 2 using synthetic ligands. | Specific and direct modulation of the interaction between adhesion GPCR GPR56/ADGRG1 and tissue transglutaminase 2 using synthetic ligands.
Salzman GS, Zhang S, Fernandez CG, Araç D, Koide S., Free PMC Article | 01/16/2021 |
| GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force. | GPR56/ADGRG1 is a platelet collagen-responsive GPCR and hemostatic sensor of shear force.
Yeung J, Adili R, Stringham EN, Luo R, Vizurraga A, Rosselli-Murai LK, Stoveken HM, Yu M, Piao X, Holinstat M, Tall GG., Free PMC Article | 01/9/2021 |
| Activation of GPR56, a novel adhesion GPCR, is necessary for nuclear androgen receptor signaling in prostate cells. | Activation of GPR56, a novel adhesion GPCR, is necessary for nuclear androgen receptor signaling in prostate cells.
Singh JP, Dagar M, Dagar G, Kumar S, Rawal S, Sharma RD, Tyagi RK, Bagchi G., Free PMC Article | 10/31/2020 |
| These findings suggest that upregulation of GPR56 may be a mechanism associated with cancer stem cells (CSC) plasticity by which LGR5((-)) cancer cells acquire a more drug-resistant phenotype. | GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism.
Zhang S, Chatterjee T, Godoy C, Wu L, Liu QJ, Carmon KS., Free PMC Article | 08/1/2020 |
| In three cohorts of individuals with depression treated with serotonin-norepinephrine reuptake inhibitor display an increase of GPR56 mRNA in the blood. | GPR56/ADGRG1 is associated with response to antidepressant treatment.
Belzeaux R, Gorgievski V, Fiori LM, Lopez JP, Grenier J, Lin R, Nagy C, Ibrahim EC, Gascon E, Courtet P, Richard-Devantoy S, Berlim M, Chachamovich E, Théroux JF, Dumas S, Giros B, Rotzinger S, Soares CN, Foster JA, Mechawar N, Tall GG, Tzavara ET, Kennedy SH, Turecki G., Free PMC Article | 07/25/2020 |
| homozygous truncating mutations in both ADGRG1/GPR56 and KIAA0556 are found in brothers displaying an overlap of polymicrogyria, hydrocephalus, and Joubert syndrome | Overlap of polymicrogyria, hydrocephalus, and Joubert syndrome in a family with novel truncating mutations in ADGRG1/GPR56 and KIAA0556.
Cauley ES, Hamed A, Mohamed IN, Elseed M, Martinez S, Yahia A, Abozar F, Abubakr R, Koko M, Elsayed L, Piao X, Salih MA, Manzini MC. | 01/11/2020 |