| Novel cell subtypes of SPP1 + S100P+, MS4A1-SPP1 + S100P+ were key subpopulations in intrahepatic cholangiocarcinoma. | Novel cell subtypes of SPP1 + S100P+, MS4A1-SPP1 + S100P+ were key subpopulations in intrahepatic cholangiocarcinoma.
Xuan Z, Liu L, Zhang G, Zheng X, Jiang J, Wang K, Huang P. | 08/14/2023 |
| MS4A1 as a Potential Independent Prognostic Factor of Breast Cancer Related to Lipid Metabolism and Immune Microenvironment Based on TCGA Database Analysis. | MS4A1 as a Potential Independent Prognostic Factor of Breast Cancer Related to Lipid Metabolism and Immune Microenvironment Based on TCGA Database Analysis.
Li S, Fang Y., Free PMC Article | 03/19/2022 |
| CD20 positive CD8 T cells are a unique and transcriptionally-distinct subset of T cells with distinct transmigration properties. | CD20 positive CD8 T cells are a unique and transcriptionally-distinct subset of T cells with distinct transmigration properties.
Vlaming M, Bilemjian V, Freile JÁ, Lourens HJ, van Rooij N, Huls G, van Meerten T, de Bruyn M, Bremer E., Free PMC Article | 01/29/2022 |
| CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles. | CD20 expression, TrkB activation and functional activity of diffuse large B cell lymphoma-derived small extracellular vesicles.
Aitamer M, Akil H, Vignoles C, Branchaud M, Abraham J, Gachard N, Feuillard J, Jauberteau MO, Shirvani H, Troutaud D, Bentayeb H., Free PMC Article | 01/15/2022 |
| Differential effects of CD20+ B cells and PD-L1+ immune cells on pathologic complete response and outcome: comparison between inflammatory breast cancer and locally advanced breast cancer patients. | Differential effects of CD20+ B cells and PD-L1+ immune cells on pathologic complete response and outcome: comparison between inflammatory breast cancer and locally advanced breast cancer patients.
Arias-Pulido H, Cimino-Mathews AM, Chaher N, Qualls CR, Joste N, Colpaert C, Marotti JD, Chamberlin MD, Foisey MG, Prossnitz ER, Emens LA, Fiering S., Free PMC Article | 11/6/2021 |
| CD20-positive primary nasal peripheral T-cell lymphoma: An analysis of one case and review of the literature. | CD20-positive primary nasal peripheral T-cell lymphoma: An analysis of one case and review of the literature.
Li YL, Wang HP, Zhang C, Zhai ZM. | 08/28/2021 |
| MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment. | MS4A1 expression and function in T cells in the colorectal cancer tumor microenvironment.
Mudd TW Jr, Lu C, Klement JD, Liu K., Free PMC Article | 06/26/2021 |
| Pharmacokinetics and safety of IBI301 versus rituximab in patients with CD20(+) B-cell lymphoma: a multicenter, randomized, double-blind, parallel-controlled study. | Pharmacokinetics and safety of IBI301 versus rituximab in patients with CD20(+) B-cell lymphoma: a multicenter, randomized, double-blind, parallel-controlled study.
Jiang B, Ke X, Zhang Q, Xu W, Su H, Huang J, Zhang M, Wang H, Jin C, Zhu J, Liu L, Cai Z, Zhao X, Zhou J, Zhang X, Liu J, Zhou H, Yu J, Sun X, Qi J, Qiu L., Free PMC Article | 12/12/2020 |
| STIM1 knock-down decreases the affinity of obinutuzumab for CD20 by altering CD20 localization to Triton-soluble membrane. | STIM1 knock-down decreases the affinity of obinutuzumab for CD20 by altering CD20 localization to Triton-soluble membrane.
Heo W, Jin N, Park MS, Kim HY, Yoon SM, Lee J, Kim JY., Free PMC Article | 10/24/2020 |
| CD20 deletion has no effect upon B-cell receptor signaling or calcium flux. Also B-cell survival and proliferation is unaffected in the absence of CD20. | CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells.
Kozlova V, Ledererova A, Ladungova A, Peschelova H, Janovska P, Slusarczyk A, Domagala J, Kopcil P, Vakulova V, Oppelt J, Bryja V, Doubek M, Mayer J, Pospisilova S, Smida M., Free PMC Article | 06/20/2020 |
| this study obtained a structure of CD20 in complex with rituximab (RTX), revealing CD20 as a compact double-barrel dimer bound by two RTX antigen-binding fragments (Fabs), each of which engages a composite epitope and an extensive homotypic Fab:Fab interface. | Structure of CD20 in complex with the therapeutic monoclonal antibody rituximab.
Rougé L, Chiang N, Steffek M, Kugel C, Croll TI, Tam C, Estevez A, Arthur CP, Koth CM, Ciferri C, Kraft E, Payandeh J, Nakamura G, Koerber JT, Rohou A. | 04/11/2020 |
| Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies. | Depletion of the transcriptional coactivators CREB-binding protein or EP300 downregulates CD20 in diffuse large B-cell lymphoma cells and impairs the cytotoxic effects of anti-CD20 antibodies.
Scialdone A, Khazaei S, Hasni MS, Lennartsson A, Gullberg U, Drott K. | 02/22/2020 |
| APOE-MS4A genetic interactions are associated with executive dysfunction and network abnormality in clinically mild Alzheimer's disease. | APOE-MS4A genetic interactions are associated with executive dysfunction and network abnormality in clinically mild Alzheimer's disease.
Chang YT, Mori E, Suzuki M, Ikeda M, Huang CW, Lee JJ, Chang WN, Chang CC., Free PMC Article | 12/14/2019 |
| Older age and CD20 expression are significant and favorable independent prognostic factors of HHV-8-negative effusion-based lymphoma. | Age and CD20 Expression Are Significant Prognostic Factors in Human Herpes Virus-8-negative Effusion-based Lymphoma.
Kubota T, Sasaki Y, Shiozawa E, Takimoto M, Hishima T, Chong JM. | 09/7/2019 |
| Case Report: indolent T-cell lymphoproliferative disorder with aberrant CD20 expression involving the gastrointestinal tract and bone marrow. | An unusual case report of indolent T-cell lymphoproliferative disorder with aberrant CD20 expression involving the gastrointestinal tract and bone marrow.
Wang X, Ng CS, Chen C, Yu G, Yin W., Free PMC Article | 03/16/2019 |
| Our study found that a small subset of papillary thyroid carcinomas (<10%, mainly of classic variant) exhibited aberrant membranous expression of CD20 | Aberrant expression of CD20 in thyroid cancer and its clinicopathologic significance.
Bychkov A, Jung CK. | 12/22/2018 |
| Our results support the fact that CD200 can be added to routine Chronic lymphoproliferative disorders panel as it is useful in subcategorizing them. However, inclusion of CD20 ABC to routine panel does not seem plausible but may be done for difficult diagnostic cases or where anti-CD20 therapy is planned. | Utility of CD200 expression and CD20 antibody binding capacity in differentiating chronic lymphocytic leukemia from other chronic lymphoproliferative disorders.
Poongodi R, Varma N, Naseem S, Parveen B, Varma S. | 11/24/2018 |
| showed here that 3' UTR NOTCH1 mutations are associated with low CD20 expression and with relative resistance to anti-CD20 immunotherapy in vitro | Mutations in the 3' untranslated region of NOTCH1 are associated with low CD20 expression levels chronic lymphocytic leukemia.
Bittolo T, Pozzo F, Bomben R, D'Agaro T, Bravin V, Bulian P, Rossi FM, Zucchetto A, Degan M, Macor P, D'Arena G, Chiarenza A, Zaja F, Pozzato G, Di Raimondo F, Rossi D, Gaidano G, Del Poeta G, Gattei V, Dal Bo M., Free PMC Article | 10/27/2018 |
| We conclude that the relationship between complement-regulatory proteins CFHR1 and CFHR3 and response to anti-CD20 mAb therapy varies based on the specific anti-CD20 mAb used. | Complement-Regulatory Proteins CFHR1 and CFHR3 and Patient Response to Anti-CD20 Monoclonal Antibody Therapy.
Rogers LM, Mott SL, Smith BJ, Link BK, Sahin D, Weiner GJ., Free PMC Article | 02/17/2018 |
| the immunohistochemical staining patterns of CD3 and CD20 in Malignant Lymphoma Cells, were investigated. | CD3 and CD20 Immunohistochemical Staining Patterns of Bone Marrow-Infiltrating Malignant Lymphoma Cells.
Lee EJ, Kim M, Kim HS, Kang HJ, Kim HJ, Min SK, Lee YK. | 02/17/2018 |
| Limiting the antibody-induced induction of immunosuppressive reactive oxygen species may improve the anti-leukemic efficacy of anti-CD20 therapy in chronic lymphocytic leukemia. | Reactive oxygen species induced by therapeutic CD20 antibodies inhibit natural killer cell-mediated antibody-dependent cellular cytotoxicity against primary CLL cells.
Werlenius O, Aurelius J, Hallner A, Akhiani AA, Simpanen M, Martner A, Andersson PO, Hellstrand K, Thorén FB., Free PMC Article | 12/23/2017 |
| Case Report: primary cutaneous T-cell lymphoma with aberrant CD20 expression. | Primary Cutaneous T-cell Lymphoma with Aberrant Expression of CD20.
Frings VG, Roth S, Riedmiller AL, Schäfer K, Goebeler M, Rosenwald A, Geissinger E, Wobser M. | 11/11/2017 |
| Data suggest that insulitis (destruction of pancreatic beta-cells and their ability to produce/secrete insulin) occurs in two distinct profiles in type 1 diabetes; these differ in proportion of CD20-positive B-lymphocytes (relative to CD4-positive T-lymphocytes) present within the infiltrate; greater infiltration of CD20-positive B-lymphocytes leads to more aggressive disease progression. | Differential Insulitic Profiles Determine the Extent of β-Cell Destruction and the Age at Onset of Type 1 Diabetes.
Leete P, Willcox A, Krogvold L, Dahl-Jørgensen K, Foulis AK, Richardson SJ, Morgan NG. | 06/10/2017 |
| PZ-DHA also arrested MDA-MB-231 cell division at the G2/M phase and down-regulated expression of cyclin B1 and cyclin-dependent kinase 1 (CDK1) | Docosahexaenoic acid-acylated phloridzin, a novel polyphenol fatty acid ester derivative, is cytotoxic to breast cancer cells.
Fernando W, Coombs MRP, Hoskin DW, Rupasinghe HPV. | 05/20/2017 |
| there is a high CD23a/CD23b ratio of chronic lymphocytic leukemia cells, which demonstrates that in a subset of CLL cases, low CD23 expression together with high CD20 and CD38 expressions may serve as a surrogate for trisomy 12 | Low CD23 expression correlates with high CD38 expression and the presence of trisomy 12 in CLL.
Kriston C, Bödör C, Szenthe K, Bánáti F, Bánkuti B, Csernus B, Reiniger L, Csomor J, Matolcsy A, Barna G. | 04/1/2017 |