| Association between LTF/MMP20/CA6/TAS1R2 polymorphisms and susceptibility to dental caries. | Association between LTF/MMP20/CA6/TAS1R2 polymorphisms and susceptibility to dental caries.
Li Y, Pan J, Li H, Liu Q, Ma F, Xiao L, Zeng X. | 09/4/2024 |
| Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma. | Lung development, repair and cancer: A study on the role of MMP20 gene in adenocarcinoma.
Mok PL, Anandasayanam ANK, Oscar David HM, Tong J, Farhana A, Khan MSA, Sivaprakasam G, Koh AE, Alzahrani B., Free PMC Article | 10/2/2021 |
| Dental malformations associated with biallelic MMP20 mutations. | Dental malformations associated with biallelic MMP20 mutations.
Wang SK, Zhang H, Chavez MB, Hu Y, Seymen F, Koruyucu M, Kasimoglu Y, Colvin CD, Kolli TN, Tan MH, Wang YL, Lu PY, Kim JW, Foster BL, Bartlett JD, Simmer JP, Hu JC., Free PMC Article | 05/15/2021 |
| The possible influence of genetic aetiological factors on molar-incisor hypomineralisation. | The possible influence of genetic aetiological factors on molar-incisor hypomineralisation.
Hočevar L, Kovač J, Podkrajšek KT, Battelino S, Pavlič A. | 01/9/2021 |
| Significantly high expression levels of MMP20 and DSPP were observed in the malignant breast, colon, prostate, thyroid, and cervical neoplasms compared with their benign and normal counterparts. Furthermore, MMP20 levels increased with advanced stages of colon and thyroid cancers. DSPP expression increased significantly with tumor stage in all cancers examined. | Survey of dentin sialophosphoprotein and its cognate matrix metalloproteinase-20 in human cancers.
Aseervatham J, Geetu S, Anunobi CC, Koli K, Ogbureke KUE., Free PMC Article | 07/4/2020 |
| AMELX and ODAM variations was not different between two populations of schoolchildren with respect to dental fluorosis (DF) severity; however, the presence of rs1784418 differed between phenotypes with regard to susceptibility to DF. Therefore, MMP20 might be related to the various phenotypes of DF | DNA sequencing reveals AMELX, ODAM and MMP20 variations in dental fluorosis.
Tremillo-Maldonado O, Molina-Frechero N, González-González R, Damián-Matsumura P, Sánchez-Pérez L, Sicco E, Suarez M, Bologna-Molina R. | 02/8/2020 |
| the minimum alleles of rs10895322, rs1784424, rs3781788, and rs1573954 correlated with an increased risk of alcohol-induced ONFH (P<0.05). Genetic model analysis revealed significant associations of 9 SNPs with alcohol-induced ONFH occurrence after adjustment for age (P<0.05): 2 protective SNPs (rs1711423 and rs1784418) and 7 high-risk SNPs (rs10895322, rs1784424, rs3781788, rs7126560, rs1573954, rs1711399, rs2292730). | MMP20 Single-Nucleotide Polymorphisms Correlate with Susceptibility to Alcohol-Induced Osteonecrosis of the Femoral Head in Chinese Males.
An F, Du J, Wang J, Zhao L, Ma C, Zhao J, Wang J., Free PMC Article | 12/7/2019 |
| The polymorphisms in MMP2, MMP9 and MMP20 genes were not statistically associated with human dental fluorosis. | Evaluation of genetic polymorphisms in MMP2, MMP9 and MMP20 in Brazilian children with dental fluorosis.
Romualdo PC, Pucinelli CM, Tannure PN, Nelson-Filho P, Segato RAB, Brancher JA, Magalhães NL, Costa MC, Antunes LAA, Antunes LS, Buzalaf MAR, Charone S, Küchler EC. | 03/16/2019 |
| The levels of MMP20 silencing-induced downregulation differed amongst CSC markers, with ABCG2 and CD44 showing more pronounced downregulations. | DSPP-MMP20 gene silencing downregulates cancer stem cell markers in human oral cancer cells.
Nikitakis NG, Gkouveris I, Aseervatham J, Barahona K, Ogbureke KUE., Free PMC Article | 10/20/2018 |
| common variants at 11q22.2 within MMP20 associate with neuroblastoma cases harboring 11q deletion (rs10895322) | Common variants in MMP20 at 11q22.2 predispose to 11q deletion and neuroblastoma risk.
Chang X, Zhao Y, Hou C, Glessner J, McDaniel L, Diamond MA, Thomas K, Li J, Wei Z, Liu Y, Guo Y, Mentch FD, Qiu H, Kim C, Evans P, Vaksman Z, Diskin SJ, Attiyeh EF, Sleiman P, Maris JM, Hakonarson H., Free PMC Article | 09/8/2018 |
| The article data showed that MMP20 rs1784418 C>T (Matrix metalloproteinase 20) appears to protect against dental caries, but its effects are likely to be more marked in certain populations. | MMP20 rs1784418 Protects Certain Populations against Caries.
Filho AV, Calixto MS, Deeley K, Santos N, Rosenblatt A, Vieira AR. | 01/20/2018 |
| DSPP-MMP20 pair may play a role in the normal turnover of cell surface proteins and/or repair of pericellular matrix proteins of the basement membranes in the metabolically active duct epithelial system of the nephrons. | Matrix Metalloproteinase 20 Co-expression With Dentin Sialophosphoprotein in Human and Monkey Kidneys.
Ogbureke KU, Koli K, Saxena G., Free PMC Article | 05/27/2017 |
| Levels of matrix metalloproteinases MMP-19 and MMP-20 expression are significantly increased in pancreatic ductal adenocarcinoma (PDAC). | High-Level Expression and Prognostic Significance of Matrix Metalloprotease-19 and Matrix Metalloprotease-20 in Human Pancreatic Ductal Adenocarcinoma.
Zhai LL, Wu Y, Cai CY, Huang Q, Tang ZG. | 04/1/2017 |
| The expression of MMP20 was lower in calcifying cystic odontogenic tumor when compared to all tumors and cysts. | Immunohistochemical expression of WNT5A and MMPs in odontogenic epithelial tumors and cysts.
Guimarães DM, Antunes DM, Saturno JL, Massuda F, Paiva KB, Nunes FD. | 09/10/2016 |
| The growth of choroidal neovascularization in AMD would be affected by 2 genes: MMP20, a newly confirmed gene expressed in the retina, and ARMS2/HTRA1, a well-known susceptibility gene for AMD. | MMP20 and ARMS2/HTRA1 Are Associated with Neovascular Lesion Size in Age-Related Macular Degeneration.
Akagi-Kurashige Y, Yamashiro K, Gotoh N, Miyake M, Morooka S, Yoshikawa M, Nakata I, Kumagai K, Tsujikawa A, Yamada R, Matsuda F, Saito M, Iida T, Sugahara M, Kurimoto Y, Cheng CY, Khor CC, Wong TY, Yoshimura N, Nagahama Cohort Research Group. | 02/6/2016 |
| Novel homozygous mutation MMP20 (c.1054G>A, p.Glu352Lys) genes were identified in amelogenesis imperfect consanguinity. Mutant MMP20 was expressed at a normal level but secreted only minimally with proteolytic function. | Novel MMP20 and KLK4 Mutations in Amelogenesis Imperfecta.
Seymen F, Park JC, Lee KE, Lee HK, Lee DS, Koruyucu M, Gencay K, Bayram M, Tuna EB, Lee ZH, Kim YJ, Kim JW. | 10/17/2015 |
| expression of MMP-20 and co-expression and potential interaction with DSPP in human major salivary gland tissues | Expression of Matrix Metalloproteinase (MMP)-20 and Potential Interaction with Dentin Sialophosphoprotein (DSPP) in Human Major Salivary Glands.
Koli K, Saxena G, Ogbureke KU. | 09/5/2015 |
| The results identify MMP-20 as a broad activator of pro-KLKs, suggesting the potential for intersection of the KLK and MMP axes under pathological dysregulation of MMP-20 expression. | Activation profiles of human kallikrein-related peptidases by matrix metalloproteinases.
Yoon H, Blaber SI, Li W, Scarisbrick IA, Blaber M., Free PMC Article | 10/4/2014 |
| Polymorphisms of MMP7 and MMP20 genes may be surrogate markers to predict long-term outcomes after kidney transplantation. | Identification of the effects of aging-related gene-matrix metalloproteinase on allograft outcomes in kidney transplantation.
Han SS, Lee H, Oh YJ, Lee JP, Kim S, Ha J, Kim SJ, Park MH, Kim YS, Kim DK. | 05/3/2014 |
| mineralized content slightly decreased; magnesium substituting for calcium in crystal. anomalies affected enamel with minimal interrod enamel; apatite crystals perpendicular to enamel prisms, suggesting possible new role for MMP20 in enamel formation. | Homozygous and compound heterozygous MMP20 mutations in amelogenesis imperfecta.
Gasse B, Karayigit E, Mathieu E, Jung S, Garret A, Huckert M, Morkmued S, Schneider C, Vidal L, Hemmerlé J, Sire JY, Bloch-Zupan A. | 08/31/2013 |
| amelogenesis imperfecta-causing mutations were identified in three of the probands: 2)a novel missense transition mutation in both MMP20 alleles (g.15390A>G; c.611A>G; p.His204Arg) that substituted arginine for histidine. | Novel KLK4 and MMP20 mutations discovered by whole-exome sequencing.
Wang SK, Hu Y, Simmer JP, Seymen F, Estrella NM, Pal S, Reid BM, Yildirim M, Bayram M, Bartlett JD, Hu JC., Free PMC Article | 04/13/2013 |
| Variation in MMP20 may be associated with caries experience mainly in Caucasian subjects with poor oral health habits. | Genetic variation in MMP20 contributes to higher caries experience.
Tannure PN, Küchler EC, Lips A, Costa Mde C, Luiz RR, Granjeiro JM, Vieira AR., Free PMC Article | 09/29/2012 |
| hypocalcified amelogenesis imperfecta, Witkop type III, was unrelated to previously described mutations in the ENAM or MMP-20 genes | A multidisciplinary approach for the diagnosis of hypocalcified amelogenesis imperfecta in two Chilean families.
Urzúa B, Ortega-Pinto A, Farias DA, Franco E, Morales-Bozo I, Moncada G, Escobar-Pezoa N, Scholz U, Cifuentes V. | 05/19/2012 |
| MMP-20 is overexpresssed in LSCC compared with the adjacent normal laryngeal epithelium. | Prognostic significance of matrix metalloproteinase-20 overexpression in laryngeal squamous cell carcinoma.
Liu Y, Li Y, Liu Z, Zhang L, Anniko M, Duan M. | 12/10/2011 |
| Associations between tooth agenesis and MMP1 (p=0.007), and MMP20 (p=0.03) were found in Brazilian families. MMP20 continued to be associated with tooth agenesis (p=0.01). Mmp20 was not expressed during the initial stages of tooth development. | MMP1 and MMP20 contribute to tooth agenesis in humans.
Küchler EC, Menezes R, Callahan N, Costa MC, Modesto A, Meira R, Patir A, Seymen F, Paiva KB, Nunes FD, Granjeiro JM, Vieira AR. | 09/24/2011 |