| CCAAT enhancer binding protein delta activates vesicle associated membrane protein 3 transcription to enhance chemoresistance and extracellular PD-L1 expression in triple-negative breast cancer. | CCAAT enhancer binding protein delta activates vesicle associated membrane protein 3 transcription to enhance chemoresistance and extracellular PD-L1 expression in triple-negative breast cancer.
Zhao Y, Yu Y, Li X, Guo A., Free PMC Article | 04/22/2024 |
| Circ_0002984 induces proliferation, migration and inflammation response of VSMCs induced by ox-LDL through miR-326-3p/VAMP3 axis in atherosclerosis. | Circ_0002984 induces proliferation, migration and inflammation response of VSMCs induced by ox-LDL through miR-326-3p/VAMP3 axis in atherosclerosis.
Li R, Jiang Q, Zheng Y., Free PMC Article | 02/19/2022 |
| this study demonstrates the role of VAMP3 in mediating cytokine secretion related to atopic dermatitis | Role of SNAREs in Atopic Dermatitis-Related Cytokine Secretion and Skin-Nerve Communication.
Meng J, Wang J, Buddenkotte J, Buhl T, Steinhoff M. | 06/13/2020 |
| Knockdown of VAMP3 and SNAP23 reduces endothelial secretion of miR-126-3p and miR-200a-3p, as well as the proliferation, migration, and suppression of contractile markers in smooth muscle cells caused by vascular endothelial cell-coculture. | VAMP3 and SNAP23 mediate the disturbed flow-induced endothelial microRNA secretion and smooth muscle hyperplasia.
Zhu JJ, Liu YF, Zhang YP, Zhao CR, Yao WJ, Li YS, Wang KC, Huang TS, Pang W, Wang XF, Wang X, Chien S, Zhou J., Free PMC Article | 05/26/2018 |
| The authors found that activation of dendritic cells by bacterial lipopolysaccharide leads to increased Forster resonance energy transfer-fluorescence of fluorescently labeled syntaxin 4 with VAMP3 specifically at the plasma membrane, indicating increased SNARE complex formation, whereas FRET with other tested SNAREs was unaltered. | Fluorescence Lifetime Imaging Microscopy reveals rerouting of SNARE trafficking driving dendritic cell activation.
Verboogen DRJ, González Mancha N, Ter Beest M, van den Bogaart G., Free PMC Article | 03/10/2018 |
| RABGEF1 mediates recycling endosome fusion with GAS-containing autophagosome-like vacuoles through the STX6-VAMP3-VTI1B complex; SNAREs are involved in autophagosome formation in response to bacterial infection | The STX6-VTI1B-VAMP3 complex facilitates xenophagy by regulating the fusion between recycling endosomes and autophagosomes.
Nozawa T, Minowa-Nozawa A, Aikawa C, Nakagawa I., Free PMC Article | 12/9/2017 |
| The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse. | The small GTPase Rab8 interacts with VAMP-3 to regulate the delivery of recycling T-cell receptors to the immune synapse.
Finetti F, Patrussi L, Galgano D, Cassioli C, Perinetti G, Pazour GJ, Baldari CT., Free PMC Article | 05/21/2016 |
| phosphatidylinositol 4-kinase IIalpha knockdown inhibited vesicle-associated membrane protein 3 trafficking to perinuclear membranes and impaired the rate of VAMP3-mediated recycling of the transferrin receptor | Endosomal sorting of VAMP3 is regulated by PI4K2A.
Jović M, Kean MJ, Dubankova A, Boura E, Gingras AC, Brill JA, Balla T., Free PMC Article | 08/15/2015 |
| highlight the role that VAMP3 and VAMP7 play in selection of the pathways leading to generation of ultrastructurally different LC3 compartments | Role of VAMP3 and VAMP7 in the commitment of Yersinia pseudotuberculosis to LC3-associated pathways involving single- or double-membrane vacuoles.
Ligeon LA, Moreau K, Barois N, Bongiovanni A, Lacorre DA, Werkmeister E, Proux-Gillardeaux V, Galli T, Lafont F., Free PMC Article | 07/25/2015 |
| Liquid chromatography-MS/MS analysis showed that the HHV-6 gM/gN complex interacts with the v-SNARE protein, vesicle-associated membrane protein 3 (VAMP3). | Human herpesvirus 6 gM/gN complex interacts with v-SNARE in infected cells.
Kawabata A, Serada S, Naka T, Mori Y. | 01/17/2015 |
| These results indicated that Uukuniemi virus relies on VAMP3 for penetration, providing an indication of added complexity in the trafficking of viruses through the endocytic network. | Genome-wide small interfering RNA screens reveal VAMP3 as a novel host factor required for Uukuniemi virus late penetration.
Meier R, Franceschini A, Horvath P, Tetard M, Mancini R, von Mering C, Helenius A, Lozach PY., Free PMC Article | 10/4/2014 |
| Genome-wide expression profiling identified the transcription of ADIPOR1, VAMP3 and C11ORF10 to be correlated with decreased ANRIL expression in a time-dependent manner. | The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10.
Bochenek G, Häsler R, El Mokhtari NE, König IR, Loos BG, Jepsen S, Rosenstiel P, Schreiber S, Schaefer AS. | 06/7/2014 |
| Data suggest VAMP3 and SNAP23 (synaptosomal-associated protein 23 kDa) participate in interleukin-1beta-, interleukin-1 receptor-, calcium signaling-dependent secretion/exocytosis of interleukin-6 and tumor necrosis factor alpha from synoviocytes. | SNAP-23 and VAMP-3 contribute to the release of IL-6 and TNFα from a human synovial sarcoma cell line.
Boddul SV, Meng J, Dolly JO, Wang J. | 04/12/2014 |
| Data suggest a new integrin trafficking pathway in which endocytosed integrins are transported from VAMP3-containing recycling endosomes to STX6-containing trans-Golgi network before being recycled to the plasma membrane. | Regulation of integrin endocytic recycling and chemotactic cell migration by syntaxin 6 and VAMP3 interaction.
Riggs KA, Hasan N, Humphrey D, Raleigh C, Nevitt C, Corbin D, Hu C., Free PMC Article | 05/18/2013 |
| mutation of the Godzilla ubiquitylation target lysines on VAMP3 abrogates the formation of enlarged endosomes induced by either Godzilla or RNF167. | Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation.
Yamazaki Y, Schönherr C, Varshney GK, Dogru M, Hallberg B, Palmer RH., Free PMC Article | 04/20/2013 |
| Endothelial cells specifically select VAMP 3 over VAMP8 to cooperate with syntaxin 4 and SNAP23 in the Ca(2+)-triggered fusion of Weibel-Palade bodies with the plasma membrane. | VAMP3 is associated with endothelial weibel-palade bodies and participates in their Ca(2+)-dependent exocytosis.
Pulido IR, Jahn R, Gerke V. | 07/23/2011 |
| the importance of VAMP3 in the trafficking of matrix metalloproteinases during degradation of extracellular matrix substrates and subsequent cellular invasion | VAMP3, syntaxin-13 and SNAP23 are involved in secretion of matrix metalloproteinases, degradation of the extracellular matrix and cell invasion.
Kean MJ, Williams KC, Skalski M, Myers D, Burtnik A, Foster D, Coppolino MG. | 07/26/2010 |
| Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator) | Identification of type 2 diabetes-associated combination of SNPs using support vector machine.
Ban HJ, Heo JY, Oh KS, Park KJ., Free PMC Article | 06/30/2010 |
| TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways. | TI-VAMP/VAMP7 and VAMP3/cellubrevin: two v-SNARE proteins involved in specific steps of the autophagy/multivesicular body pathways.
Fader CM, Sánchez DG, Mestre MB, Colombo MI. | 03/1/2010 |
| VAMP3-dependent integrin trafficking is crucial in cell migration and cell adhesion to laminin. | Silencing of VAMP3 inhibits cell migration and integrin-mediated adhesion.
Luftman K, Hasan N, Day P, Hardee D, Hu C., Free PMC Article | 01/21/2010 |
| These results do not suggest that a common genetic variant at VAMP2 or VAMP3 contributes to the development of bipolar affective disorder in German patients. | Association study between genetic variants at the VAMP2 and VAMP3 loci and bipolar affective disorder.
Abou Jamra R, Gobina CM, Becker T, Georgi A, Schulze TG, Schmael C, Cichon S, Propping P, Rietschel M, Nöthen MM, Schumacher J, Abou Jamra R, Gobina CM, Becker T, Georgi A, Schulze TG, Schmael C, Cichon S, Propping P, Rietschel M, Nöthen MM, Schumacher J. | 01/21/2010 |
| Observational study of gene-disease association. (HuGE Navigator) | Association study between genetic variants at the VAMP2 and VAMP3 loci and bipolar affective disorder.
Abou Jamra R, Gobina CM, Becker T, Georgi A, Schulze TG, Schmael C, Cichon S, Propping P, Rietschel M, Nöthen MM, Schumacher J, Abou Jamra R, Gobina CM, Becker T, Georgi A, Schulze TG, Schmael C, Cichon S, Propping P, Rietschel M, Nöthen MM, Schumacher J. | 07/30/2008 |
| VAMP-3 and VAMP-8 are present in human platelets and are required for granule secretion. | Vesicle-associated membrane protein 3 (VAMP-3) and VAMP-8 are present in human platelets and are required for granule secretion.
Polgár J, Chung SH, Reed GL. | 01/21/2010 |
| Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells | Hyperacidification of cellubrevin endocytic compartments and defective endosomal recycling in cystic fibrosis respiratory epithelial cells.
Poschet JF, Skidmore J, Boucher JC, Firoved AM, Van Dyke RW, Deretic V. | 01/21/2010 |