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    MUC16 mucin 16, cell surface associated [ Homo sapiens (human) ]

    Gene ID: 94025, updated on 3-Nov-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    Gender and melanoma subtype-based prognostic implications of MUC16 and TTN co-occurrent mutations in melanoma: A retrospective multi-study analysis.

    Gender and melanoma subtype-based prognostic implications of MUC16 and TTN co-occurrent mutations in melanoma: A retrospective multi-study analysis.
    Kodali N, Alomary S, Bhattaru A, Eldaboush A, Schwartz RA, Lipner SR., Free PMC Article

    10/28/2024
    TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.

    TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.
    Yamada Y, Terada Y, Yamanaka R, Enoyoshi M, Ito K.

    09/3/2024
    Human Epididymis Protein 4 (HE4) and Cancer Antigen 125 (CA125) for Prediction of Optimal Primary Surgery in Non-Mucinous Epithelial Ovarian Cancer.

    Human Epididymis Protein 4 (HE4) and Cancer Antigen 125 (CA125) for Prediction of Optimal Primary Surgery in Non-Mucinous Epithelial Ovarian Cancer.
    Promchit K, Oranratanaphan S., Free PMC Article

    02/21/2024
    Comprehensive characterization of MUC16 mutations in lung adenocarcinoma for immunotherapies and prognosis: An observational study.

    Comprehensive characterization of MUC16 mutations in lung adenocarcinoma for immunotherapies and prognosis: An observational study.
    Liu T, Wu L, Liu J, Chen H, Zhu B, Qiao D, Zhu Y, Liu T, Chen Q, Hu A., Free PMC Article

    11/28/2023
    Development and validation of a MUC16 mutation-associated immune prognostic model for lung adenocarcinoma.

    Development and validation of a MUC16 mutation-associated immune prognostic model for lung adenocarcinoma.
    Liu H, Xin T, Duan H, Wang Y, Shao C, Zhu Y, Wang J, He J., Free PMC Article

    10/20/2023
    Serum CA-125 as a predictor in the early diagnosis of ectopic pregnancy in Vietnam - A case-control study.

    Serum CA-125 as a predictor in the early diagnosis of ectopic pregnancy in Vietnam - A case-control study.
    Tran NBT, Cao TN, Nguyen QHV, Truong LGT, Tran LM, Tran Nguyen TN, Le TM.

    09/15/2023
    MUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer.

    MUC16 stimulates neutrophils to an inflammatory and immunosuppressive phenotype in ovarian cancer.
    Wu Y, Liu Q, Xie Y, Zhu J, Zhang S, Ge Y, Guo J, Luo N, Huang W, Xu R, Liu S, Cheng Z., Free PMC Article

    09/6/2023
    Diagnostic value of serum human epididymis protein 4, carbohydrate antigen 125 and their combination in endometrial cancer: A meta-analysis.

    Diagnostic value of serum human epididymis protein 4, carbohydrate antigen 125 and their combination in endometrial cancer: A meta-analysis.
    Wu Q, Bai SN, Song LY, Wu WF, Han LN., Free PMC Article

    08/25/2023
    Radiologically enlarged cardiophrenic lymph nodes and CA-125 in relation to diaphragmatic carcinomatosis, surgical outcome, and overall survival in advanced ovarian cancer.

    Radiologically enlarged cardiophrenic lymph nodes and CA-125 in relation to diaphragmatic carcinomatosis, surgical outcome, and overall survival in advanced ovarian cancer.
    Plana A, Talo R, Wallengren NO, Pudaric S, Sartor H, Asp M.

    06/13/2023
    Diffusion-weighted magnetic resonance sequence and CA125/CEA ratio can be used as add-on tools to ultrasound for the differentiation of ovarian from non-ovarian pelvic masses.

    Diffusion-weighted magnetic resonance sequence and CA125/CEA ratio can be used as add-on tools to ultrasound for the differentiation of ovarian from non-ovarian pelvic masses.
    Nunes Pereira P, Françoise Derchain S, Yoshida A, Hoelz de Oliveira Barros R, Menezes Jales R, Sarian LO., Free PMC Article

    04/4/2023
    The Utility of Preoperative Serum CA125 Combined with HE4 to Predict Lymph Node Metastasis in Endometrial Cancer.

    The Utility of Preoperative Serum CA125 Combined with HE4 to Predict Lymph Node Metastasis in Endometrial Cancer.
    Prueksaritanond N, Angsathapon S, Insin P.

    03/30/2023
    MUC16 promotes triple-negative breast cancer lung metastasis by modulating RNA-binding protein ELAVL1/HUR.

    MUC16 promotes triple-negative breast cancer lung metastasis by modulating RNA-binding protein ELAVL1/HUR.
    Chaudhary S, Appadurai MI, Maurya SK, Nallasamy P, Marimuthu S, Shah A, Atri P, Ramakanth CV, Lele SM, Seshacharyulu P, Ponnusamy MP, Nasser MW, Ganti AK, Batra SK, Lakshmanan I., Free PMC Article

    03/22/2023
    CA125: a novel cardiac biomarker for infants with congenital diaphragmatic hernia.

    CA125: a novel cardiac biomarker for infants with congenital diaphragmatic hernia.
    Schroeder L, Pugnaloni F, Dolscheid-Pommerich R, Geipel A, Berg C, Holdenrieder S, Mueller A, Kipfmueller F., Free PMC Article

    03/14/2023
    Cancer Antigen 125 Expression Enhances the Gemcitabine/Cisplatin-Resistant Tumor Microenvironment in Bladder Cancer.

    Cancer Antigen 125 Expression Enhances the Gemcitabine/Cisplatin-Resistant Tumor Microenvironment in Bladder Cancer.
    Yamashita T, Higashi M, Sugiyama H, Morozumi M, Momose S, Tamaru JI.

    03/8/2023
    MUC16 mutation is associated with tumor grade, clinical features, and prognosis in glioma patients.

    MUC16 mutation is associated with tumor grade, clinical features, and prognosis in glioma patients.
    Ferrer VP.

    01/7/2023
    The clinical and prognostic significance of pre-chemotherapy serum CA-125 in high-risk early stage ovarian cancer: An NRG/GOG ancillary study.

    The clinical and prognostic significance of pre-chemotherapy serum CA-125 in high-risk early stage ovarian cancer: An NRG/GOG ancillary study.
    Chan JK, Tian C, Kesterson JP, Richardson MT, Lin K, Tewari KS, Herzog T, Kapp DS, Monk BJ, Casablanca Y, Hanjani P, Wenham RM, Walker J, McNally L, Copeland LJ, Robertson S, Lentz S, Spirtos NM, Bell JG.

    12/31/2022
    Prognostic value of carbohydrate antigen 125 in patients undergoing surgical left ventricular reconstruction.

    Prognostic value of carbohydrate antigen 125 in patients undergoing surgical left ventricular reconstruction.
    Nan Y, Tiemuerniyazi X, Chen L, Song Y, Feng W, Xu F.

    12/31/2022
    CA125 as a predictor of endometrial cancer lymphovascular space invasion and lymph node metastasis for risk stratification in the preoperative setting.

    CA125 as a predictor of endometrial cancer lymphovascular space invasion and lymph node metastasis for risk stratification in the preoperative setting.
    Shawn LyBarger K, Miller HA, Frieboes HB., Free PMC Article

    11/26/2022
    Relationship between the serum cancer antigen 125 level and the weight of surgically enucleated adenomyosis.

    Relationship between the serum cancer antigen 125 level and the weight of surgically enucleated adenomyosis.
    Itagaki H, Nishida M, Kodaira Y, Sakanaka M, Ichikawa R, Arai Y, Satoh T.

    10/8/2022
    Bioinformatics Analysis Based on TCGA: MUC16 Mutation Correlates with Clinical Outcome in Gastric Cancer.

    Bioinformatics Analysis Based on TCGA: MUC16 Mutation Correlates with Clinical Outcome in Gastric Cancer.
    Huang L, Zheng S, Fu J, Zhang M, Ge X, Mu N., Free PMC Article

    09/10/2022
    MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion.

    MUC16 Promotes Liver Metastasis of Pancreatic Ductal Adenocarcinoma by Upregulating NRP2-Associated Cell Adhesion.
    Marimuthu S, Lakshmanan I, Muniyan S, Gautam SK, Nimmakayala RK, Rauth S, Atri P, Shah A, Bhyravbhatla N, Mallya K, Grandgenett PM, Hollingsworth MA, Datta K, Jain M, Ponnusamy MP, Batra SK., Free PMC Article

    08/13/2022
    Ovarian Cancer Ascites Inhibits Transcriptional Activation of NK Cells Partly through CA125.

    Ovarian Cancer Ascites Inhibits Transcriptional Activation of NK Cells Partly through CA125.
    Fraser CC, Jia B, Hu G, Al Johani LI, Fritz-Klaus R, Ham JD, Fichorova RN, Elias KM, Cramer DW, Patankar MS, Chen J., Free PMC Article

    07/2/2022
    Truncated O-Glycan-Bearing MUC16 Enhances Pancreatic Cancer Cells Aggressiveness via alpha4beta1 Integrin Complexes and FAK Signaling.

    Truncated O-Glycan-Bearing MUC16 Enhances Pancreatic Cancer Cells Aggressiveness via α4β1 Integrin Complexes and FAK Signaling.
    Rajesh C, Sagar S, Rathinavel AK, Chemparathy DT, Peng XL, Yeh JJ, Hollingsworth MA, Radhakrishnan P., Free PMC Article

    06/11/2022
    Mucin 16 Promotes Colorectal Cancer Development and Progression Through Activation of Janus Kinase 2.

    Mucin 16 Promotes Colorectal Cancer Development and Progression Through Activation of Janus Kinase 2.
    Liu Z, Gu Y, Li X, Zhou L, Cheng X, Jiang H, Huang Y, Zhang Y, Xu T, Yang W, Huang Q.

    06/11/2022
    Crystal structure of a human MUC16 SEA domain reveals insight into the nature of the CA125 tumor marker.

    Crystal structure of a human MUC16 SEA domain reveals insight into the nature of the CA125 tumor marker.
    White B, Patterson M, Karnwal S, Brooks CL., Free PMC Article

    04/16/2022
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