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    CD38 CD38 molecule [ Homo sapiens (human) ]

    Gene ID: 952, updated on 28-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CD38 in SLE CD4 T cells promotes Ca[2+] flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane.

    CD38 in SLE CD4 T cells promotes Ca(2+) flux and suppresses interleukin-2 production by enhancing the expression of GM2 on the surface membrane.
    Katsuyama E, Humbel M, Suarez-Fueyo A, Satyam A, Yoshida N, Kyttaris VC, Tsokos MG, Tsokos GC., Free PMC Article

    10/5/2024
    CD38 genetic variation is associated with increased personal distress to an emotional stimulus.

    CD38 genetic variation is associated with increased personal distress to an emotional stimulus.
    Procyshyn TL, Leclerc Bédard LA, Crespi BJ, Bartz JA., Free PMC Article

    06/26/2024
    Increased expression of CD38 on endothelial cells in SARS-CoV-2 infection in cynomolgus macaques.

    Increased expression of CD38 on endothelial cells in SARS-CoV-2 infection in cynomolgus macaques.
    Nguyen CT, Nakayama M, Ishigaki H, Kitagawa Y, Kakino A, Ohno M, Shingai M, Suzuki Y, Sawamura T, Kida H, Itoh Y.

    04/12/2024
    CD38 promotes hematopoietic stem cell dormancy.

    CD38 promotes hematopoietic stem cell dormancy.
    Ibneeva L, Singh SP, Sinha A, Eski SE, Wehner R, Rupp L, Kovtun I, Pérez-Valencia JA, Gerbaulet A, Reinhardt S, Wobus M, von Bonin M, Sancho J, Lund F, Dahl A, Schmitz M, Bornhäuser M, Chavakis T, Wielockx B, Grinenko T., Free PMC Article

    03/29/2024
    Evaluation of diagnostic potential of CD38 in rickets.

    Evaluation of diagnostic potential of CD38 in rickets.
    Xia Y, Ye X, Chen W, You C, Deng C, Zhou Y.

    02/28/2024
    Frequent, high density expression of surface CD38 as a potential therapeutic target in adult T-lineage acute lymphoblastic leukemia.

    Frequent, high density expression of surface CD38 as a potential therapeutic target in adult T-lineage acute lymphoblastic leukemia.
    Koslowski S, Glauben R, Habringer S, Burmeister T, Keller U, Brüggemann M, Gökbuget N, Schwartz S., Free PMC Article

    02/2/2024
    CD38 gene polymorphism rs1130169 contribution to the increased gene expression and risk of colorectal cancer (pilot study).

    CD38 gene polymorphism rs1130169 contribution to the increased gene expression and risk of colorectal cancer (pilot study).
    Novikov DV, Perenkov AD, Shumilova SV, Kubysheva NI, Novikov VV.

    01/9/2024
    Acquired CD38 gene deletion as a mechanism of tumor antigen escape in multiple myeloma.

    Acquired CD38 gene deletion as a mechanism of tumor antigen escape in multiple myeloma.
    Portuguese AJ, Fang M, Tuazon SA, Pont M, Qu X, Shasha C, Comstock M, Lyons J, Cole G, Newell EW, Glynn E, Soma LA, Green DJ., Free PMC Article

    12/1/2023
    Prognostic Impact of CD38- and IgkappaC-Positive Tumor-Infiltrating Plasma Cells in Triple-Negative Breast Cancer.

    Prognostic Impact of CD38- and IgκC-Positive Tumor-Infiltrating Plasma Cells in Triple-Negative Breast Cancer.
    Heimes AS, Riedel N, Almstedt K, Krajnak S, Schwab R, Stewen K, Lebrecht A, Battista MJ, Brenner W, Hasenburg A, Schmidt M., Free PMC Article

    10/30/2023
    A Population of Tumor-Infiltrating CD4+ T Cells Co-Expressing CD38 and CD39 Is Associated with Checkpoint Inhibitor Resistance.

    A Population of Tumor-Infiltrating CD4+ T Cells Co-Expressing CD38 and CD39 Is Associated with Checkpoint Inhibitor Resistance.
    Mitra A, Thompson B, Strange A, Amato CM, Vassallo M, Dolgalev I, Hester-McCullough J, Muramatsu T, Kimono D, Puranik AS, Weber JS, Woods D., Free PMC Article

    10/28/2023
    CD38 as a pan-hematologic target for chimeric antigen receptor T cells.

    CD38 as a pan-hematologic target for chimeric antigen receptor T cells.
    Glisovic-Aplenc T, Diorio C, Chukinas JA, Veliz K, Shestova O, Shen F, Nunez-Cruz S, Vincent TL, Miao F, Milone MC, June CH, Teachey DT, Tasian SK, Aplenc R, Gill S., Free PMC Article

    08/14/2023
    Clonally expanded CD38[hi] cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis.

    Clonally expanded CD38(hi) cytotoxic CD8 T cells define the T cell infiltrate in checkpoint inhibitor-associated arthritis.
    Wang R, Singaraju A, Marks KE, Shakib L, Dunlap G, Adejoorin I, Greisen SR, Chen L, Tirpack AK, Aude C, Fein MR, Todd DJ, MacFarlane L, Goodman SM, DiCarlo EF, Massarotti EM, Sparks JA, Jonsson AH, Brenner MB, Postow MA, Chan KK, Bass AR, Donlin LT, Rao DA., Free PMC Article

    08/14/2023
    Mass cytometry uncovers a distinct peripheral immune profile and upregulated CD38 expression in patients with hidradenitis suppurativa.

    Mass cytometry uncovers a distinct peripheral immune profile and upregulated CD38 expression in patients with hidradenitis suppurativa.
    Dimitrion P, Hamzavi I, Yin C, Toor J, Subedi K, Khalasawi N, Miller A, Huggins R, Adrianto I, Veenstra J, Vellaichamy G, Hans A, Daveluy S, Athar M, Liao W, Lim H, Ozog D, Zhou L, Mi QS., Free PMC Article

    08/2/2023
    Cytokine receptor IL27RA is an NF-kappaB-responsive gene involved in CD38 upregulation in multiple myeloma.

    Cytokine receptor IL27RA is an NF-κB-responsive gene involved in CD38 upregulation in multiple myeloma.
    Brownlie RJ, Kennedy R, Wilson EB, Milanovic M, Taylor CF, Wang D, Davies JR, Owston H, Adams EJ, Stephenson S, Caeser R, Gewurz BE, Giannoudis PV, Scuoppo C, McGonagle D, Hodson DJ, Tooze RM, Doody GM, Cook G, Westhead DR, Klein U., Free PMC Article

    07/31/2023
    CD38: an ecto-enzyme with functional diversity in T cells.

    CD38: an ecto-enzyme with functional diversity in T cells.
    Ghosh A, Khanam A, Ray K, Mathur P, Subramanian A, Poonia B, Kottilil S., Free PMC Article

    05/23/2023
    Comprehensive Proteomics Analysis Identifies CD38-Mediated NAD[+] Decline Orchestrating Renal Fibrosis in Pediatric Patients With Obstructive Nephropathy.

    Comprehensive Proteomics Analysis Identifies CD38-Mediated NAD(+) Decline Orchestrating Renal Fibrosis in Pediatric Patients With Obstructive Nephropathy.
    Tao Y, Wang J, Lyu X, Li N, Lai D, Liu Y, Zhang X, Li P, Cao S, Zhou X, Zhao Y, Ma L, Tao T, Feng Z, Li X, Yang F, Zhou H., Free PMC Article

    03/29/2023
    The potential of CD38 protein as a target for autoimmune diseases.

    The potential of CD38 protein as a target for autoimmune diseases.
    Ye X, Zhao Y, Ma W, Ares I, Martínez M, Lopez-Torres B, Martínez-Larrañaga MR, Wang X, Anadón A, Martínez MA.

    03/23/2023
    The Role of CD38 in the Pathogenesis of Cardiorenal Metabolic Disease and Aging, an Approach from Basic Research.

    The Role of CD38 in the Pathogenesis of Cardiorenal Metabolic Disease and Aging, an Approach from Basic Research.
    Kitada M, Araki SI, Koya D., Free PMC Article

    03/2/2023
    Mechanism of CD38 via NAD[+] in the Development of Non-alcoholic Fatty Liver Disease.

    Mechanism of CD38 via NAD(+) in the Development of Non-alcoholic Fatty Liver Disease.
    Dong M, Wang S, Pei Z., Free PMC Article

    02/17/2023
    [Oxytocin genetic pathway (CD38) and SDQ psychosocial characteristics in adolescent schoolchildren].

    [Oxytocin genetic pathway (CD38) and SDQ psychosocial characteristics in adolescent schoolchildren].
    Tereshchenko SU, Azanova AV, Shubina MV, Gorbacheva NN.

    12/3/2022
    A Combined Biomarker of Bright CD38 and MYC >/=55% Is Highly Predictive of Double-/Triple-Hit High-Grade B-Cell Lymphoma.

    A Combined Biomarker of Bright CD38 and MYC ≥55% Is Highly Predictive of Double-/Triple-Hit High-Grade B-Cell Lymphoma.
    Alsuwaidan A, Koduru P, Fuda F, Manuel Jaso J, Chen M, Rosado F, Luu HS, Sweed N, Garcia R, Doucet M, Desai NB, Kumar KA, Awan FT, Ramakrishnan Geethakumari P, Chen W.

    09/17/2022
    CD38: An important regulator of T cell function.

    CD38: An important regulator of T cell function.
    Li W, Liang L, Liao Q, Li Y, Zhou Y.

    09/17/2022
    CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.

    CD38 Mediates Lung Fibrosis by Promoting Alveolar Epithelial Cell Aging.
    Cui H, Xie N, Banerjee S, Dey T, Liu RM, Antony VB, Sanders YY, Adams TS, Gomez JL, Thannickal VJ, Kaminski N, Liu G.

    08/27/2022
    Human CD38 regulates B cell antigen receptor dynamic organization in normal and malignant B cells.

    Human CD38 regulates B cell antigen receptor dynamic organization in normal and malignant B cells.
    Camponeschi A, Kläsener K, Sundell T, Lundqvist C, Manna PT, Ayoubzadeh N, Sundqvist M, Thorarinsdottir K, Gatto M, Visentini M, Önnheim K, Aranburu A, Forsman H, Ekwall O, Fogelstrand L, Gjertsson I, Reth M, Mårtensson IL., Free PMC Article

    07/23/2022
    Lymphocyte HLA-DR/CD-38 co-expression correlates with Hodgkin lymphoma cell cytotoxicity in vitro independent of PD-1/PD1-L pathway.

    Lymphocyte HLA-DR/CD-38 co-expression correlates with Hodgkin lymphoma cell cytotoxicity in vitro independent of PD-1/PD1-L pathway.
    Henry M, Buck S, Al-Qanber B, Gadgeel M, Savaşan S.

    06/11/2022
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