| High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer. | High Level of GMFG Correlated to Poor Clinical Outcome and Promoted Cell Migration and Invasion through EMT Pathway in Triple-Negative Breast Cancer.
Zhao Y, Wei X, Li J, Diao Y, Shan C, Li W, Zhang S, Wu F., Free PMC Article | 06/30/2023 |
| GMFG (glia maturation factor gamma) inhibits lung cancer growth by activating p53 signaling pathway. | GMFG (glia maturation factor gamma) inhibits lung cancer growth by activating p53 signaling pathway.
Tang H, Liu J, Huang J., Free PMC Article | 07/9/2022 |
| RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression. | RNF144A exerts tumor suppressor function in breast cancer through targeting YY1 for proteasomal degradation to downregulate GMFG expression.
Zhang YL, Cao JL, Zhang Y, Liao L, Deng L, Yang SY, Hu SY, Ning Y, Zhang FL, Li DQ., Free PMC Article | 03/26/2022 |
| Bioinformatics and survival analysis of glia maturation factor-gamma in pan-cancers. | Bioinformatics and survival analysis of glia maturation factor-γ in pan-cancers.
Lan A, Ren C, Wang X, Tong G, Yang G., Free PMC Article | 05/15/2021 |
| GMFgamma phosphorylation by c-Abl has an important role in coordinating lamellipodial and focal adhesion dynamics to regulate cell migration | Phosphorylation of GMFγ by c-Abl Coordinates Lamellipodial and Focal Adhesion Dynamics to Regulate Airway Smooth Muscle Cell Migration.
Gerlach BD, Tubbesing K, Liao G, Rezey AC, Wang R, Barroso M, Tang DD., Free PMC Article | 04/11/2020 |
| High GMF-GAMMA expression is associated with colorectal cancer metastasis. | Expression of glia maturation factor γ is associated with colorectal cancer metastasis and its downregulation suppresses colorectal cancer cell migration and invasion in vitro.
Wang H, Chen Z, Chang H, Mu X, Deng W, Yuan Z, Yao F, Liu Y, Mai R, Wu B. | 04/15/2017 |
| These results indicate that the effects of GMFG on monocyte migration and adhesion probably occur through preventing ubiquitin-mediated proteasome degradation of alpha5beta1-integrin and facilitating effective beta1-integrin recycling back to the plasma membrane. | Glia Maturation Factor-γ Regulates Monocyte Migration through Modulation of β1-Integrin.
Aerbajinai W, Liu L, Zhu J, Kumkhaek C, Chin K, Rodgers GP., Free PMC Article | 10/8/2016 |
| In this study, knockdown of GMF-gamma by RNA interference enhanced actin polymerization and contraction in human airway smooth muscle (HASM) cells and tissues without affecting myosin phosphorylation. | Glia maturation factor-γ phosphorylation at Tyr-104 regulates actin dynamics and contraction in human airway smooth muscle.
Wang T, Cleary RA, Wang R, Tang DD., Free PMC Article | 01/3/2015 |
| Together, the results suggest that GMFG functions by a mechanism similar to that of other ADF/cofilin family members, displaying a preference for ADP-Arp2/3 complex and undergoing inhibition by phosphorylation of a serine residue near the N terminus. | Glia maturation factor (GMF) interacts with Arp2/3 complex in a nucleotide state-dependent manner.
Boczkowska M, Rebowski G, Dominguez R., Free PMC Article | 02/8/2014 |
| our findings suggest that GMFG functions as a negative regulator of TLR4 signaling by facilitating TLR4 endocytic trafficking in macrophages | Glia maturation factor-γ negatively modulates TLR4 signaling by facilitating TLR4 endocytic trafficking in macrophages.
Aerbajinai W, Lee K, Chin K, Rodgers GP., Free PMC Article | 08/31/2013 |
| regulates the migration and adherence of human T lymphocytes | Glia maturation factor gamma regulates the migration and adherence of human T lymphocytes.
Lippert DN, Wilkins JA., Free PMC Article | 02/9/2013 |
| characterized the promoter region and found the putative cis-acting regulatory elements responsible for promoter activity | Structure and promoter activity of the human glia maturation factor-gamma gene: a TATA-less, GC-rich and bidirectional promoter.
Kawai Y, Asai K, Miura Y, Inoue Y, Yamamoto M, Moriyama A, Yamamoto N, Kato T. | 01/21/2010 |
| GMFG is a hematopoietic-specific protein that may mediate the pluripotentiality and lineage commitment of human hematopoietic stem cells | Glia maturation factor gamma (GMFG): a cytokine-responsive protein during hematopoietic lineage development and its functional genomics analysis.
Shi Y, Chen L, Liotta LA, Wan HH, Rodgers GP., Free PMC Article | 01/21/2010 |