| miR483 promotes the development of colorectal cancer by inhibiting the expression level of EI24. | miR‑483 promotes the development of colorectal cancer by inhibiting the expression level of EI24.
Zhou W, Yang W, Yang J, Zhu H, Duan L, Wang X, Li Y, Niu L, Xiao S, Zhang R, Yang J, Hong L. | 11/6/2021 |
| EI24 is a prognostic biomarker and impacts poor outcome in non-small cell lung cancer. | Integrated analysis of the prognostic value of TP53 dependent etoposide-induced gene 24 in non-small cell lung cancer.
Wang M, Li P, Wan R, Liu X. | 07/27/2019 |
| EI24 is an essential player in ubiquitin-proteasome system-autophagy crosstalk via degradation of RING E3 ligases. | Functional characterization of EI24-induced autophagy in the degradation of RING-domain E3 ligases.
Devkota S, Jeong H, Kim Y, Ali M, Roh JI, Hwang D, Lee HW., Free PMC Article | 11/18/2017 |
| Low EI24 expression is associated with triple negative breast cancer. | MicroRNA-455-3p promotes invasion and migration in triple negative breast cancer by targeting tumor suppressor EI24.
Li Z, Meng Q, Pan A, Wu X, Cui J, Wang Y, Li L., Free PMC Article | 10/14/2017 |
| Low EI24 and high IGF-1R expressions in lung cancer patients. | Reduced expression of EI24 confers resistance to gefitinib through IGF-1R signaling in PC9 NSCLC cells.
Choi JM, Jang JY, Choi YR, Kim HR, Cho BC, Lee HW. | 08/6/2016 |
| Findings establish EI24 as a critical suppressor of tumor progression. | EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-κB activity.
Choi JM, Devkota S, Sung YH, Lee HW., Free PMC Article | 11/22/2014 |
| Ei24 can bind specifically to IMPbeta1 and IMPalpha2 to impede their normal role in nuclear import. | The p53-induced factor Ei24 inhibits nuclear import through an importin β-binding-like domain.
Lieu KG, Shim EH, Wang J, Lokareddy RK, Tao T, Cingolani G, Zambetti GP, Jans DA., Free PMC Article | 06/28/2014 |
| Ei24 is a novel E2F1 target gene contributing to the survival of p53-deficient cells upon UVC irradiation and thus may have a potential significance as a therapeutic target of certain chemotherapy for treating p53-deficient tumors. | Ei24, a novel E2F target gene, affects p53-independent cell death upon ultraviolet C irradiation.
Sung YH, Jin Y, Kang Y, Devkota S, Lee J, Roh JI, Lee HW., Free PMC Article | 01/4/2014 |
| our data suggest that inactivation of EI24 and CHEK1 through two independent mechanisms contributes to the development of CACX. | Inactivation of CHEK1 and EI24 is associated with the development of invasive cervical carcinoma: clinical and prognostic implications.
Mazumder Indra D, Mitra S, Singh RK, Dutta S, Roy A, Mondal RK, Basu PS, Roychoudhury S, Panda CK. | 09/15/2012 |
| LOH11CR2A, PIG8 and CHEK1 are candidate tumor suppressor genes associated with breast carcinoma and have significant clinical as well as prognostic importance. | Frequent alterations of LOH11CR2A, PIG8 and CHEK1 genes at chromosomal 11q24.1-24.2 region in breast carcinoma: clinical and prognostic implications.
Sinha S, Singh RK, Bhattacharya N, Mukherjee N, Ghosh S, Alam N, Roy A, Roychoudhury S, Panda CK., Free PMC Article | 04/21/2012 |
| identify the EI24/PIG8 status as a potentially new prognostic marker of chemotherapy responsiveness | Loss of putative tumor suppressor EI24/PIG8 confers resistance to etoposide.
Mork CN, Faller DV, Spanjaard RA., Free PMC Article | 01/21/2010 |