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    RAB3D RAB3D, member RAS oncogene family [ Homo sapiens (human) ]

    Gene ID: 9545, updated on 17-Jun-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CircECE1 promotes osteosarcoma progression through regulating RAB3D by sponging miR-588.

    CircECE1 promotes osteosarcoma progression through regulating RAB3D by sponging miR-588.
    Liang Z, Shi Y, Guan Z., Free PMC Article

    08/11/2023
    [miR-125b-5p inhibits proliferation and migration of osteosarcoma cells by negatively regulating RAB3D expression].

    [miR-125b-5p inhibits proliferation and migration of osteosarcoma cells by negatively regulating RAB3D expression].
    Tan Q, Wu X, Ji F, Wu S, Yan L., Free PMC Article

    03/3/2023
    Hsa_circ_0006732 regulates colorectal cancer cell proliferation, invasion and EMT by miR-127-5p/RAB3D axis.

    Hsa_circ_0006732 regulates colorectal cancer cell proliferation, invasion and EMT by miR-127-5p/RAB3D axis.
    Yang T, Sun J, Wang W, Li D, Yang X, Jia A, Ma Y, Fan Z.

    11/26/2022
    Hsa_circ_0103232 promotes melanoma cells proliferation and invasion via targeting miR-661/RAB3D.

    Hsa_circ_0103232 promotes melanoma cells proliferation and invasion via targeting miR-661/RAB3D.
    Lin X, Zhong L, Wang N, Chu X, Liu B., Free PMC Article

    08/13/2022
    Rab3 proteins and cancer: Exit strategies.

    Rab3 proteins and cancer: Exit strategies.
    Raffaniello RD.

    02/19/2022
    GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.

    GDP/GTP exchange factor MADD drives activation and recruitment of secretory Rab GTPases to Weibel-Palade bodies.
    Kat M, Bürgisser PE, Janssen H, De Cuyper IM, Conte IL, Hume AN, Carter T, Voorberg J, Margadant C, Bierings R., Free PMC Article

    01/15/2022
    Long non-coding RNA FGD5-AS1 enhances osteosarcoma cell proliferation and migration by targeting miR-506-3p/RAB3D axis.

    Long non-coding RNA FGD5-AS1 enhances osteosarcoma cell proliferation and migration by targeting miR-506-3p/RAB3D axis.
    Li C, Lin X, Zhang C, Wan L, Yin J, Wang B.

    11/6/2021
    targeting the Rab3D may be a potential therapeutic target for treatment of esophageal squamous cell carcinoma.

    Silencing of Rab3D suppresses the proliferation and invasion of esophageal squamous cell carcinoma cells.
    Zhang J, Kong R, Sun L.

    03/31/2018
    increased Rab3D expression is associated with invasiveness of CRC cells

    High expression of Rab3D predicts poor prognosis and associates with tumor progression in colorectal cancer.
    Luo Y, Ye GY, Qin SL, Mu YF, Zhang L, Qi Y, Qiu YE, Yu MH, Zhong M.

    09/30/2017
    High expression of small GTPase Rab3D promotes cancer progression and metastasis.

    High expression of small GTPase Rab3D promotes cancer progression and metastasis.
    Yang J, Liu W, Lu X, Fu Y, Li L, Luo Y., Free PMC Article

    03/19/2016
    The presence of Rab3D(N135I) decreases the restriction of maturing secretory granules (SGs) to the F-actin-rich cell cortex, blocks the removal of the endoprotease furin from SGs and impedes the processing of the luminal SG protein secretogranin II.

    Rab3D is critical for secretory granule maturation in PC12 cells.
    Kögel T, Rudolf R, Hodneland E, Copier J, Regazzi R, Tooze SA, Gerdes HH., Free PMC Article

    09/21/2013
    Our findings indicate that Rab3D regulates the exocytosis of many components critical for the maintenance of oral physiology.

    Changes in Rab3D expression and distribution in the acini of Sjögren's syndrome patients are associated with loss of cell polarity and secretory dysfunction.
    Bahamondes V, Albornoz A, Aguilera S, Alliende C, Molina C, Castro I, Urzúa U, Quest AF, Barrera MJ, González S, Sánchez M, Härtel S, Hermoso M, Leyton C, González MJ.

    01/26/2013
    Observational study of gene-disease association. (HuGE Navigator)

    Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.
    Hendrickson SL, Lautenberger JA, Chinn LW, Malasky M, Sezgin E, Kingsley LA, Goedert JJ, Kirk GD, Gomperts ED, Buchbinder SP, Troyer JL, O'Brien SJ., Free PMC Article

    12/5/2010
    MIST1 binds to highly conserved CATATG E-boxes to directly activate transcription of 6 genes, including those encoding the small GTPases RAB26 and RAB3D.

    RAB26 and RAB3D are direct transcriptional targets of MIST1 that regulate exocrine granule maturation.
    Tian X, Jin RU, Bredemeyer AJ, Oates EJ, Błazewska KM, McKenna CE, Mills JC., Free PMC Article

    03/29/2010
    mutant Rab3D proteins interfere with the formation of bona fide Weibel-Palade bodies and consequently the acute, histamine-induced release of von-Willebrand factor

    Rab3D and annexin A2 play a role in regulated secretion of vWF, but not tPA, from endothelial cells.
    Knop M, Aareskjold E, Bode G, Gerke V., Free PMC Article

    01/21/2010
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