| Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes. | Resistin stimulates PC-3 prostate cancer cell growth through stimulation of SOCS3 and SOCS5 genes.
Liu CW, Peng HY, Siao AC, Tsuei YW, Lin YY, Shiah SG, Shih LJ, Yeh CC, Lee SW, Kao YH., Free PMC Article | 01/6/2024 |
| Sequential inspiratory muscle exercise-noninvasive positive pressure ventilation alleviates oxidative stress in COPD by mediating SOCS5/JAK2/STAT3 pathway. | Sequential inspiratory muscle exercise-noninvasive positive pressure ventilation alleviates oxidative stress in COPD by mediating SOCS5/JAK2/STAT3 pathway.
Lei Y, He J, Hu F, Zhu H, Gu J, Tang L, Luo M., Free PMC Article | 11/2/2023 |
| Evaluation of SOCS5 mRNA and its association with serum IL-12 levels and rs41379147 SNP in various subsets of allergic disorders: A case control study. | Evaluation of SOCS5 mRNA and its association with serum IL-12 levels and rs41379147 SNP in various subsets of allergic disorders: A case control study.
Hussain S, Rasool R, Shafi T, Gull A, Qureshi TA, Jan R, Shah ZA. | 09/20/2023 |
| SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy. | SOCS5 contributes to temozolomide resistance in glioblastoma by regulating Bcl-2-mediated autophagy.
Yu J, Han L, Yang F, Zhao M, Zhou H, Hu L., Free PMC Article | 06/25/2022 |
| Inhibition of microRNA-448 suppresses CD4(+) T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus. | Inhibition of microRNA-448 suppresses CD4(+) T cell inflammatory activation via up-regulating suppressor of cytokine signaling 5 in systemic lupus erythematosus.
Zhang J, Guo Y, Sun Y, Chang L, Wang X. | 03/19/2022 |
| LncRNA DHRS4-AS1 ameliorates hepatocellular carcinoma by suppressing proliferation and promoting apoptosis via miR-522-3p/SOCS5 axis. | LncRNA DHRS4-AS1 ameliorates hepatocellular carcinoma by suppressing proliferation and promoting apoptosis via miR-522-3p/SOCS5 axis.
Zhou Y, Li K, Zou X, Hua Z, Wang H, Bian W, Wang H, Chen F, Dai T., Free PMC Article | 02/19/2022 |
| Long non-coding RNA HCG11 sponging miR-522-3p inhibits the tumorigenesis of non-small cell lung cancer by upregulating SOCS5. | Long non-coding RNA HCG11 sponging miR-522-3p inhibits the tumorigenesis of non-small cell lung cancer by upregulating SOCS5.
Fan G, Jiao J, Shen F, Ren Q, Wang Q, Chu F., Free PMC Article | 08/14/2021 |
| LncRNA CASC2 inhibits cell proliferation, metastasis and EMT through miR-18a/SOCS5 axis in cholangiocarcinoma. | LncRNA CASC2 inhibits cell proliferation, metastasis and EMT through miR-18a/SOCS5 axis in cholangiocarcinoma.
Peng L, Liu YH, Nie S, Gao M. | 05/8/2021 |
| miR-802 participates in the inflammatory process of inflammatory bowel disease by suppressing SOCS5. | miR-802 participates in the inflammatory process of inflammatory bowel disease by suppressing SOCS5.
Yao J, Gao R, Luo M, Li D, Guo L, Yu Z, Xiong F, Wei C, Wu B, Xu Z, Zhang D, Wang J, Wang L., Free PMC Article | 04/3/2021 |
| lncRNA HAND2-AS1 Inhibits Liver Cancer Cell Proliferation and Migration by Upregulating SOCS5 to Inactivate the JAK-STAT Pathway. | lncRNA HAND2-AS1 Inhibits Liver Cancer Cell Proliferation and Migration by Upregulating SOCS5 to Inactivate the JAK-STAT Pathway.
Yan D, Jin F, Lin Y. | 11/28/2020 |
| MicroRNA-301a promotes pancreatic cancer invasion and metastasis through the JAK/STAT3 signaling pathway by targeting SOCS5. | MicroRNA-301a promotes pancreatic cancer invasion and metastasis through the JAK/STAT3 signaling pathway by targeting SOCS5.
Hu H, Zhang Q, Chen W, Wu T, Liu S, Li X, Luo B, Zhang T, Yan G, Lu H, Lu Z. | 10/31/2020 |
| MiR-9-5p could promote angiogenesis and radiosensitivity in cervical cancer by targeting SOCS5. | MiR-9-5p could promote angiogenesis and radiosensitivity in cervical cancer by targeting SOCS5.
Wei YQ, Jiao XL, Zhang SY, Xu Y, Li S, Kong BH. | 10/10/2020 |
| This study revealed a novel metastasis-promoting function of SOCS5 in hepatocellular carcinoma. | SOCS5 inhibition induces autophagy to impair metastasis in hepatocellular carcinoma cells via the PI3K/Akt/mTOR pathway.
Zhang M, Liu S, Chua MS, Li H, Luo D, Wang S, Zhang S, Han B, Sun C., Free PMC Article | 08/1/2020 |
| data indicated thatthe overexpression of FER1L4 promoted apoptosis and inhibited the EMT markers expression and PI3K/AKT signaling pathway activation in OS cells via downregulating miR-18a-5p to promote SOCS5. | LncRNA FER1L4 induces apoptosis and suppresses EMT and the activation of PI3K/AKT pathway in osteosarcoma cells via inhibiting miR-18a-5p to promote SOCS5.
Ye F, Tian L, Zhou Q, Feng D. | 11/9/2019 |
| Mechanistic investigations demonstrated that TUSC7 can interact with miR-616 and decrease its expression, thereby upregulating the expression of miR-616's targets SOCS4 (SOCS5). | Long noncoding RNA TUSC7 inhibits cell proliferation, migration and invasion by regulating SOCS4 (SOCS5) expression through targeting miR-616 in endometrial carcinoma.
Wu X, Cai D, Zhang F, Li M, Wan Q. | 09/21/2019 |
| Homozygous genotype of capital ES, Cyrilliccapital ES, Cyrillic gene of SOCS5 is a risk factor for allergic bronchial asthma | Association of SOCS5 gene polymorphism with allergic bronchial asthma.
Averyanov AB, Chercashina II, Nikulina SY, Maksimov VN, Shestovitskiy VA. | 08/24/2019 |
| Data show that suppressor of cytokine signaling 5 (SOCS5) was differentially expressed in primary T-cell leukemia, acute (T-ALL). | Epigenetic silencing of SOCS5 potentiates JAK-STAT signaling and progression of T-cell acute lymphoblastic leukemia.
Sharma ND, Nickl CK, Kang H, Ornatowski W, Brown R, Ness SA, Loh ML, Mullighan CG, Winter SS, Hunger SP, Cannon JL, Matlawska-Wasowska K., Free PMC Article | 06/29/2019 |
| We validated SOCS5 as a bona fide target of mir-18 and mir-25, and established, for the first time, the tumor suppressive role of SOCS5 in liver cancer | A novel SOCS5/miR-18/miR-25 axis promotes tumorigenesis in liver cancer.
Sanchez-Mejias A, Kwon J, Chew XH, Siemens A, Sohn HS, Jing G, Zhang B, Yang H, Tay Y. | 04/6/2019 |
| our data implicated that miR-132 may promote inflammation...via targeting SOCS5 in chronic obstructive pulmonary disease | Upregulation of miR-132 contributes to the pathophysiology of COPD via targeting SOCS5.
Diao X, Zhou J, Wang S, Ma X. | 01/5/2019 |
| These findings indicate that SOCS5 mediates the impaired function of dendritic cells in chronic lymphocytic leukemia patients | Deregulation of SOCS5 suppresses dendritic cell function in chronic lymphocytic leukemia.
Toniolo PA, Liu S, Yeh JE, Ye DQ, Barbuto JA, Frank DA., Free PMC Article | 02/3/2018 |
| Data show that the Japanese encephalitis virus (JEV)-induced expression of miR-301a led to inhibition of the production of the transcription factor IFN regulatory factor 1 (IRF1) and the signaling protein suppressor of cytokine signaling 5 (SOCS5). | The host microRNA miR-301a blocks the IRF1-mediated neuronal innate immune response to Japanese encephalitis virus infection.
Hazra B, Kumawat KL, Basu A. | 12/2/2017 |
| Here the authors show that suppressor of cytokine signaling (SOCS) five has a pivotal role in restricting influenza A virus in the airway epithelium, through the regulation of epidermal growth factor receptor (EGFR). | Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling.
Kedzierski L, Tate MD, Hsu AC, Kolesnik TB, Linossi EM, Dagley L, Dong Z, Freeman S, Infusini G, Starkey MR, Bird NL, Chatfield SM, Babon JJ, Huntington N, Belz G, Webb A, Wark PA, Nicola NA, Xu J, Kedzierska K, Hansbro PM, Nicholson SE., Free PMC Article | 11/18/2017 |
| This study showed that SOCS5 expression was significantly down-regulated. | SOCS gene family expression profile in the blood of multiple sclerosis patients.
Toghi M, Taheri M, Arsang-Jang S, Ohadi M, Mirfakhraie R, Mazdeh M, Sayad A. | 07/8/2017 |
| Opisthorchis felineus infection diminishes the risk of atopic bronchial asthma associated with the SOCS5 gene polymorphism. | Opisthorchis felineus liver fluke invasion is an environmental factor modifying genetic risk of atopic bronchial asthma.
Saltykova IV, Ogorodova LM, Bragina EY, Puzyrev VP, Freidin MB. | 03/21/2015 |
| different domains in SOCS5 contribute to two distinct mechanisms for regulation of cytokine and growth factor signaling with JAK1 and SHC-1 | Suppressor of Cytokine Signaling (SOCS) 5 utilises distinct domains for regulation of JAK1 and interaction with the adaptor protein Shc-1.
Linossi EM, Chandrashekaran IR, Kolesnik TB, Murphy JM, Webb AI, Willson TA, Kedzierski L, Bullock AN, Babon JJ, Norton RS, Nicola NA, Nicholson SE., Free PMC Article | 04/26/2014 |