The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection. | The cargo adapter protein CLINT1 is phosphorylated by the Numb-associated kinase BIKE and mediates dengue virus infection. Schor S, Pu S, Nicolaescu V, Azari S, Kõivomägi M, Karim M, Cassonnet P, Saul S, Neveu G, Yueh A, Demeret C, Skotheim JM, Jacob Y, Randall G, Einav S., Free PMC Article | 07/2/2022 |
Although epsinR has been shown to be a cargo adaptor, the present study indicates that it is an order of magnitude more abundant in CCVs than its known cargo protein, vti1b, suggesting that it may have other functions as well. | Contributions of epsinR and gadkin to clathrin-mediated intracellular trafficking. Hirst J, Edgar JR, Borner GH, Li S, Sahlender DA, Antrobus R, Robinson MS., Free PMC Article | 06/11/2016 |
These results do not support a significant role of GRIA1 or CLINT1 in the development of schizophrenia in the German population. | Association study of the GRIA1 and CLINT1 (Epsin 4) genes in a German schizophrenia sample. Leon CA, Schumacher J, Kluck N, Herold C, Schulze TG, Propping P, Rietschel M, Cichon S, Nöthen MM, Jamra RA. | 01/21/2012 |
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR., Free PMC Article | 06/30/2010 |
Variation in the Epsin 4 gene is significantly associated with psychotic disorder in this Latino population | The epsin 4 gene is associated with psychotic disorders in families of Latin American origin. Escamilla M, Lee BD, Ontiveros A, Raventos H, Nicolini H, Mendoza R, Jerez A, Munoz R, Medina R, Figueroa A, Walss-Bass C, Armas R, Contreras S, Ramirez ME, Dassori A, Escamilla M, Lee BD, Ontiveros A, Raventos H, Nicolini H, Mendoza R, Jerez A, Munoz R, Medina R, Figueroa A, Walss-Bass C, Armas R, Contreras S, Ramirez ME, Dassori A. | 01/21/2010 |
Our results suggest that the examined region of Epsin 4 does not have a major influence on susceptibility to schizophrenia in Japanese. | Failure to confirm an association between Epsin 4 and schizophrenia in a Japanese population. Richards M, Iijima Y, Shizuno T, Kamegaya Y, Hori H, Omori M, Arima K, Saitoh O, Kunugi H, Richards M, Iijima Y, Shizuno T, Kamegaya Y, Hori H, Omori M, Arima K, Saitoh O, Kunugi H. | 01/21/2010 |
Observational study of gene-disease association. (HuGE Navigator) | See all PubMed (3) articlesComprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients. Saus E, Brunet A, Armengol L, Alonso P, Crespo JM, Fernández-Aranda F, Guitart M, Martín-Santos R, Menchón JM, Navinés R, Soria V, Torrens M, Urretavizcaya M, Vallès V, Gratacòs M, Estivill X. The epsin 4 gene is associated with psychotic disorders in families of Latin American origin. Escamilla M, Lee BD, Ontiveros A, Raventos H, Nicolini H, Mendoza R, Jerez A, Munoz R, Medina R, Figueroa A, Walss-Bass C, Armas R, Contreras S, Ramirez ME, Dassori A, Escamilla M, Lee BD, Ontiveros A, Raventos H, Nicolini H, Mendoza R, Jerez A, Munoz R, Medina R, Figueroa A, Walss-Bass C, Armas R, Contreras S, Ramirez ME, Dassori A. Failure to confirm an association between Epsin 4 and schizophrenia in a Japanese population. Richards M, Iijima Y, Shizuno T, Kamegaya Y, Hori H, Omori M, Arima K, Saitoh O, Kunugi H, Richards M, Iijima Y, Shizuno T, Kamegaya Y, Hori H, Omori M, Arima K, Saitoh O, Kunugi H. | 08/20/2008 |
characterization of the molecular details governing the sorting of a SNARE into clathrin-coated vesicles, namely the direct recognition of the three-helical bundle H(abc) domain of the mouse SNARE Vti1b by the human clathrin adaptor epsinR | A SNARE-adaptor interaction is a new mode of cargo recognition in clathrin-coated vesicles. Miller SE, Collins BM, McCoy AJ, Robinson MS, Owen DJ. | 01/21/2010 |
might participate in the formation of clathrin-coated vesicles at the level of the trans-Golgi network and remains associated with the vesicles longer than clathrin and adaptors | Clint: a novel clathrin-binding ENTH-domain protein at the Golgi. Kalthoff C, Groos S, Kohl R, Mahrhold S, Ungewickell EJ., Free PMC Article | 01/21/2010 |
epsinR is an adaptor for vesicle-associated soluble NSF attachment protein receptor | EpsinR is an adaptor for the SNARE protein Vti1b. Hirst J, Miller SE, Taylor MJ, von Mollard GF, Robinson MS., Free PMC Article | 01/21/2010 |
Four adjacent markers at the 5' end of the Epsin 4 gene showed significant evidence of linkage disequilibrium with schizophrenia. | The Epsin 4 gene on chromosome 5q, which encodes the clathrin-associated protein enthoprotin, is involved in the genetic susceptibility to schizophrenia. Pimm J, McQuillin A, Thirumalai S, Lawrence J, Quested D, Bass N, Lamb G, Moorey H, Datta SR, Kalsi G, Badacsonyi A, Kelly K, Morgan J, Punukollu B, Curtis D, Gurling H., Free PMC Article | 01/21/2010 |
a novel clathrin-associated protein identified through subcellular proteomics; data suggest a role in clathrin-mediated budding on internal membranes | Enthoprotin: a novel clathrin-associated protein identified through subcellular proteomics. Wasiak S, Legendre-Guillemin V, Puertollano R, Blondeau F, Girard M, de Heuvel E, Boismenu D, Bell AW, Bonifacino JS, McPherson PS., Free PMC Article | 01/21/2010 |
Our work reveals the existence of clathrin-independent and -dependent transport steps in the retrograde route, and establishes a function for clathrin and epsinR at the endosome-TGN interface. | Clathrin adaptor epsinR is required for retrograde sorting on early endosomal membranes. Saint-Pol A, Yélamos B, Amessou M, Mills IG, Dugast M, Tenza D, Schu P, Antony C, McMahon HT, Lamaze C, Johannes L. | 01/21/2010 |
Results indicate the presence of a locus near the 5' end of Epsin 4 conferring susceptibility to the disease and provide further support for Epsin 4 as an important potential contributor to genetic risk in schizophrenia. | Family-based association study of Epsin 4 and Schizophrenia. Tang RQ, Zhao XZ, Shi YY, Tang W, Gu NF, Feng GY, Xing YL, Zhu SM, Sang H, Liang PJ, He L. | 01/21/2010 |
EpsinR is an ENTH domain-containing protein that interacts with AP-1 | EpsinR: an ENTH domain-containing protein that interacts with AP-1. Hirst J, Motley A, Harasaki K, Peak Chew SY, Robinson MS., Free PMC Article | 01/21/2010 |