| Soluble CD27 as a predictive biomarker for intra-tumoral CD70/CD27 interaction in nasopharyngeal carcinoma. | Soluble CD27 as a predictive biomarker for intra-tumoral CD70/CD27 interaction in nasopharyngeal carcinoma.
Nagato T, Komatsuda H, Hayashi R, Takahara M, Ujiie N, Kosaka A, Ohkuri T, Oikawa K, Sato R, Wakisaka R, Kono M, Yamaki H, Ohara K, Kumai T, Kishibe K, Katada A, Hayashi T, Kobayashi H., Free PMC Article | 04/24/2024 |
| Associations between CD70 methylation of T cell DNA and age in adults with systemic lupus erythematosus and population controls: The Michigan Lupus Epidemiology & Surveillance (MILES) Program. | Associations between CD70 methylation of T cell DNA and age in adults with systemic lupus erythematosus and population controls: The Michigan Lupus Epidemiology & Surveillance (MILES) Program.
Somers EC, Goodrich JM, Wang L, Harlow SD, Marder W, Hassett AL, Zick SM, McCune WJ, Gordon C, Barbour KE, Helmick CG, Strickland FM., | 03/27/2024 |
| Delayed vaccine-induced CD8[+] T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication. | Delayed vaccine-induced CD8(+) T cell expansion by topoisomerase I inhibition mediates enhanced CD70-dependent tumor eradication.
van der Sluis TC, van Haften FJ, van Duikeren S, Pardieck IN, de Graaf JF, Vleeshouwers W, van der Maaden K, Melief CJM, van der Burg SH, Arens R., Free PMC Article | 12/4/2023 |
| CD70-induced differentiation of proinflammatory Th1/17/22/GM lymphocytes associated with disease progression and immune reconstitution during HIV infection. | CD70-induced differentiation of proinflammatory Th1/17/22/GM lymphocytes associated with disease progression and immune reconstitution during HIV infection.
Wang X, Wei Y, He Z, Wang D, Zhang L, Du J, Zhang M, Jiang M, Chen N, Deng M, Li B, Song C, Chen D, Liu H, Xiao J, Liang H, Zhao H, Kong Y., Free PMC Article | 11/1/2023 |
| The correlation of CD70 in immune characteristics and drug therapy of pan-cancer. | The correlation of CD70 in immune characteristics and drug therapy of pan-cancer.
Yang Y, Chen J, Feng M, Wang Y, Liao W, Wu Q, Wen F, Li Q. | 01/21/2023 |
| The dual role of CD70 in B-cell lymphomagenesis. | The dual role of CD70 in B-cell lymphomagenesis.
Nie M, Ren W, Ye X, Berglund M, Wang X, Fjordén K, Du L, Giannoula Y, Lei D, Su W, Li W, Liu D, Linderoth J, Jiang C, Bao H, Jiang W, Huang H, Hou Y, Zhu S, Enblad G, Jerkeman M, Wu K, Zhang H, Amini RM, Li ZM, Pan-Hammarström Q., Free PMC Article | 12/17/2022 |
| Expression of CD70 Modulates Nitric Oxide and Redox Status in Endothelial Cells. | Expression of CD70 Modulates Nitric Oxide and Redox Status in Endothelial Cells.
Pandey AK, Waldeck-Weiermair M, Wells QS, Xiao W, Yadav S, Eroglu E, Michel T, Loscalzo J., Free PMC Article | 09/3/2022 |
| Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer. | Epithelial-to-mesenchymal transition promotes immune escape by inducing CD70 in non-small cell lung cancer.
Ortiz-Cuaran S, Swalduz A, Foy JP, Marteau S, Morel AP, Fauvet F, De Souza G, Michon L, Boussageon M, Gadot N, Godefroy M, Léon S, Tortereau A, Mourksi NE, Leonce C, Albaret MA, Dongre A, Vanbervliet B, Robert M, Tonon L, Pommier RM, Hofman V, Attignon V, Boyault S, Audoynaud C, Auclair J, Bouquet F, Wang Q, Ménétrier-Caux C, Pérol M, Caux C, Hofman P, Lantuejoul S, Puisieux A, Saintigny P. | 06/18/2022 |
| Hypoxia-Inducible Factor-2 Alpha Regulates the Migration of Fibroblast-like Synoviocytes via Oxidative Stress-Induced CD70 Expression in Patients with Rheumatoid Arthritis. | Hypoxia-Inducible Factor-2 Alpha Regulates the Migration of Fibroblast-like Synoviocytes via Oxidative Stress-Induced CD70 Expression in Patients with Rheumatoid Arthritis.
Yoo SJ, Lee HR, Kim J, Yoo IS, Park CK, Kang SW., Free PMC Article | 04/16/2022 |
| DNA Methylation of CD70 Promoter in Juvenile Systemic Lupus Erythematosus. | DNA Methylation of CD70 Promoter in Juvenile Systemic Lupus Erythematosus.
Keshavarz-Fathi M, Sanati G, Sadr M, Mohebbi B, Ziaee V, Rezaei N. | 02/12/2022 |
| SOX11, CD70, and Treg cells configure the tumor-immune microenvironment of aggressive mantle cell lymphoma. | SOX11, CD70, and Treg cells configure the tumor-immune microenvironment of aggressive mantle cell lymphoma.
Balsas P, Veloza L, Clot G, Sureda-Gómez M, Rodríguez ML, Masaoutis C, Frigola G, Navarro A, Beà S, Nadeu F, Giné E, López-Guillermo A, Martínez A, Ribera-Cortada I, Engel P, Quintanilla-Martínez L, Klapper W, Campo E, Amador V., Free PMC Article | 01/8/2022 |
| CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity. | CD70-specific CAR T cells have potent activity against acute myeloid leukemia without HSC toxicity.
Sauer T, Parikh K, Sharma S, Omer B, Sedloev D, Chen Q, Angenendt L, Schliemann C, Schmitt M, Müller-Tidow C, Gottschalk S, Rooney CM., Free PMC Article | 12/4/2021 |
| Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex. | Structural delineation and phase-dependent activation of the costimulatory CD27:CD70 complex.
Liu W, Maben Z, Wang C, Lindquist KC, Li M, Rayannavar V, Lopez Armenta I, Nager A, Pascua E, Dominik PK, Oyen D, Wang H, Roach RC, Allan CM, Mosyak L, Chaparro-Riggers J., Free PMC Article | 11/27/2021 |
| Clinical relevance of CD70 expression in resected pancreatic cancer: Prognostic value and therapeutic potential. | Clinical relevance of CD70 expression in resected pancreatic cancer: Prognostic value and therapeutic potential.
Nakamura K, Sho M, Akahori T, Nishiwada S, Kunishige T, Nakagawa K, Nagai M, Takagi T, Terai T, Ikeda N. | 11/22/2021 |
| CD70 Deficiency Associated With Chronic Epstein-Barr Virus Infection, Recurrent Airway Infections and Severe Gingivitis in a 24-Year-Old Woman. | CD70 Deficiency Associated With Chronic Epstein-Barr Virus Infection, Recurrent Airway Infections and Severe Gingivitis in a 24-Year-Old Woman.
Krüger R, Martin E, Dmytrus J, Feiterna-Sperling C, Meisel C, Unterwalder N, Kölsch U, Wahn V, Hofmann J, Korn P, Latour S, Boztug K, von Bernuth H., Free PMC Article | 04/24/2021 |
| CD70 antibody-drug conjugate as a potential therapeutic agent for uterine leiomyosarcoma. | CD70 antibody-drug conjugate as a potential therapeutic agent for uterine leiomyosarcoma.
Nakae R, Matsuzaki S, Serada S, Matsuo K, Shiomi M, Sato K, Nagase Y, Matsuzaki S, Nakagawa S, Hiramatsu K, Okazawa A, Kimura T, Egawa-Takata T, Kobayashi E, Ueda Y, Yoshino K, Naka T, Kimura T. | 02/20/2021 |
| CD70 Activation Decreases Pulmonary Fibroblast Production of Extracellular Matrix Proteins. | CD70 Activation Decreases Pulmonary Fibroblast Production of Extracellular Matrix Proteins.
Tran-Nguyen TK, Xue J, Feghali-Bostwick C, Sciurba FC, Kass DJ, Duncan SR., Free PMC Article | 10/24/2020 |
| CD8+CD70+ T cells combined with CD8+CD27+perforin+ T cells may serve as potential immune biomarkers for estimating the severity of AA. | Increased CD8(+)CD27(+)perforin(+) T cells and decreased CD8(+)CD70(+) T cells may be immune biomarkers for aplastic anemia severity.
Zhao S, Zhang Y, Huang G, Luo W, Li Y, Xiao Y, Zhou M, Li Y, Lai J, Li Y, Li B. | 01/18/2020 |
| The down-regulation of hsa_circ_0012919, the sponge for miR-125a-3p, contributes to DNA methylation of CD11a and CD70 in CD4(+) T cells of systemic lupus erythematous. | The down-regulation of hsa_circ_0012919, the sponge for miR-125a-3p, contributes to DNA methylation of CD11a and CD70 in CD4(+) T cells of systemic lupus erythematous.
Zhang C, Wang X, Chen Y, Wu Z, Zhang C, Shi W. | 09/21/2019 |
| that both human and mouse CD70-specific CAR T cells recognize primary CD70+ glioblastomas (GBM) tumors in vitro and mediate the regression of established GBM in xenograft and syngeneic models without illicit effect | CD70, a novel target of CAR T-cell therapy for gliomas.
Jin L, Ge H, Long Y, Yang C, Chang YE, Mu L, Sayour EJ, De Leon G, Wang QJ, Yang JC, Kubilis PS, Bao H, Xia S, Lu D, Kong Y, Hu L, Shang Y, Jiang C, Nie J, Li S, Gu Y, Sun J, Mitchell DA, Lin Z, Huang J., Free PMC Article | 02/2/2019 |
| This dose-escalation phase I trial provides evidence of good tolerability of ARGX-110, pharmacokinetics, and preliminary antitumor activity at all dose levels in generally heavily pretreated patients with advanced CD70-positive malignancies | Phase I Dose-Escalation Study of the Anti-CD70 Antibody ARGX-110 in Advanced Malignancies.
Aftimos P, Rolfo C, Rottey S, Offner F, Bron D, Maerevoet M, Soria JC, Moshir M, Dreier T, Van Rompaey L, Michot JM, Silence K, Hultberg A, Gandini D, de Haard H, Ribrag V, Peeters M, Thibault A, Leupin N, Awada A. | 07/28/2018 |
| Results show that CD70 promoter region methylation and expression are regulated by MBD4. Indeed, the study shows that downregulation of MBD4 contributed to overexpression and hypomethylation of the CD70 gene in CD4+ T cells from patients from systemic lupus erythematosus. | Down-regulation of MBD4 contributes to hypomethylation and overexpression of CD70 in CD4(+) T cells in systemic lupus erythematosus.
Liao W, Li M, Wu H, Jia S, Zhang N, Dai Y, Zhao M, Lu Q., Free PMC Article | 06/2/2018 |
| CD70 mitigates atherosclerosis at least in part by modulating macrophage function. | CD70 limits atherosclerosis and promotes macrophage function.
Winkels H, Meiler S, Smeets E, Lievens D, Engel D, Spitz C, Bürger C, Rinne P, Beckers L, Dandl A, Reim S, Ahmadsei M, Van den Bossche J, Holdt LM, Megens RT, Schmitt M, de Winther M, Biessen EA, Borst J, Faussner A, Weber C, Lutgens E, Gerdes N. | 03/3/2018 |
| Preclinical testing supports the safety and efficacy of a CD27-containing CAR targeting CD70-expressing tumors | Preclinical Evaluation of Chimeric Antigen Receptors Targeting CD70-Expressing Cancers.
Wang QJ, Yu Z, Hanada KI, Patel K, Kleiner D, Restifo NP, Yang JC., Free PMC Article | 02/24/2018 |
| This study demonstrated that Expression of CD70 (CD27L) Is Associated With Epithelioid and Sarcomatous Features in IDH-Wild-Type Glioblastoma. | Expression of CD70 (CD27L) Is Associated With Epithelioid and Sarcomatous Features in IDH-Wild-Type Glioblastoma.
Pratt D, Pittaluga S, Palisoc M, Fetsch P, Xi L, Raffeld M, Gilbert MR, Quezado M., Free PMC Article | 08/26/2017 |