U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CD72 CD72 molecule [ Homo sapiens (human) ]

    Gene ID: 971, updated on 10-Oct-2024

    GeneRIFs: Gene References Into Functions

    GeneRIFPubMed TitleDate
    CD72 is a pan-tumor antigen associated to pediatric acute leukemia.

    CD72 is a pan-tumor antigen associated to pediatric acute leukemia.
    Buldini B, Faggin G, Porcù E, Scarparo P, Polato K, Tregnago C, Varotto E, Rizzardi P, Rizzari C, Locatelli F, Biffi A, Pigazzi M.

    01/3/2024
    CD72, a new immune checkpoint molecule, is a novel prognostic biomarker for kidney renal clear cell carcinoma.

    CD72, a new immune checkpoint molecule, is a novel prognostic biomarker for kidney renal clear cell carcinoma.
    Tian L, Wang Y, Zhang Z, Feng X, Xiao F, Zong M., Free PMC Article

    11/22/2023
    CD72-semaphorin3A axis: A new regulatory pathway in systemic lupus erythematosus.

    CD72-semaphorin3A axis: A new regulatory pathway in systemic lupus erythematosus.
    Eiza N, Sabag AD, Kessler O, Neufeld G, Vadasz Z.

    02/14/2023
    Blockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion.

    Blockage of CD72 reduces B cell proliferation in immune thrombocytopenic purpura, involving interleukin 1 and macrophage migration inhibitory factor secretion.
    Xu J, Du J, Zhong Y, Zhang H, Zhou L, Yao Q.

    11/12/2022
    CD40 and CD72 expression and prognostic values among children with systemic lupus erythematosus: a case-control study.

    CD40 and CD72 expression and prognostic values among children with systemic lupus erythematosus: a case-control study.
    Asmiyou A, Bakr AM, Shahin DA, Wahba Y.

    06/12/2021
    A regulatory role for CD72 expression on B cells and increased soluble CD72 in primary Sjogren's syndrome.

    A regulatory role for CD72 expression on B cells and increased soluble CD72 in primary Sjogren's syndrome.
    Shen Y, Ma Y, Xie J, Lin L, Shi Y, Li X, Shen P, Pan X, Ren H., Free PMC Article

    06/5/2021
    Interferon-alpha-induced CD100 expression on naive CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.

    Interferon-α-induced CD100 on naïve CD8(+) T cells enhances antiviral responses to hepatitis C infection through CD72 signal transduction.
    Li BJ, He Y, Zhang Y, Guo YH, Zhou Y, Zhang PX, Wang W, Zhao JR, Li JG, Zuo WZ, Fan C, Jia ZS., Free PMC Article

    05/20/2017
    Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis

    Increased soluble CD72 in systemic lupus erythematosus is in association with disease activity and lupus nephritis.
    Vadasz Z, Goldeberg Y, Halasz K, Rosner I, Valesini G, Conti F, Perricone C, Sthoeger Z, Bezalel SR, Tzioufas AG, Levin NA, Shoenfeld Y, Toubi E.

    07/30/2016
    CD72 expression on activated B cells of SLE patients was significantly lower than that of normal controls. sema3A enhanced CD72 expression of B cells, but it was still lower in SLE patients than in normal individuals.

    A regulatory role for CD72 expression on B cells in systemic lupus erythematosus.
    Vadasz Z, Haj T, Balbir A, Peri R, Rosner I, Slobodin G, Kessel A, Toubi E.

    02/7/2015
    data demonstrated aberrant expression of CD72 exists on B cells of myasthenia gravis and multiple sclerosis patients and expression level of CD72 molecule has a significantly negative correlation with anti-AchR antibody levels in myasthenia gravis

    Modulation of B cell regulatory molecules CD22 and CD72 in myasthenia gravis and multiple sclerosis.
    Lu J, Li J, Zhu TQ, Zhang L, Wang Y, Tian FF, Yang H.

    02/15/2014
    regulates serum immunoglobulin leveln and disease resistance in systemic lupus erythematosus

    Human CD72 splicing isoform responsible for resistance to systemic lupus erythematosus regulates serum immunoglobulin level and is localized in endoplasmic reticulum.
    Hitomi Y, Adachi T, Tsuchiya N, Honda Z, Tokunaga K, Tsubata T., Free PMC Article

    07/20/2013
    CD72 mRNA expression level correlates with Sema4D expression in peripheral blood mononuclear cells in immune thrombocytopenia.

    CD72 gene expression in immune thrombocytopenia.
    Zhou H, Qi AP, Li HY, Ma L, Xu JH, Xue F, Lu SH, Zhao QJ, Zhou ZP, Yang RC.

    04/20/2013
    Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)

    Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
    Bailey SD, Xie C, Do R, Montpetit A, Diaz R, Mohan V, Keavney B, Yusuf S, Gerstein HC, Engert JC, Anand S, DREAM investigators., Free PMC Article

    09/15/2010
    CD100-CD72 interaction can be the mechanism by which NK cell communicate with B cells.

    CD100 on NK cells enhance IFNgamma secretion and killing of target cells expressing CD72.
    Mizrahi S, Markel G, Porgador A, Bushkin Y, Mandelboim O., Free PMC Article

    06/14/2010
    Data show that ligation of CD72 with the BU40, or with rCD100 negatively regulates KIT-mediated mast cell proliferation, chemotaxis, and chemokine production.

    CD72 negatively regulates KIT-mediated responses in human mast cells.
    Kataoka TR, Kumanogoh A, Bandara G, Metcalfe DD, Gilfillan AM., Free PMC Article

    05/10/2010
    CD72 polymorphisms are associated with age of appearing clinical manifestations in idiopathic thrombocytopenic purpura in Chinese patients.

    CD72 polymorphism associated with child-onset of idiopathic thrombocytopenic purpura in Chinese patients.
    Xu J, Lu S, Tao J, Zhou Z, Chen Z, Huang Y, Yang R, Xu J, Lu S, Tao J, Zhou Z, Chen Z, Huang Y, Yang R.

    01/21/2010
    Observational study of gene-disease association. (HuGE Navigator)See all PubMed (4) articles

    New genetic associations detected in a host response study to hepatitis B vaccine.
    Davila S, Froeling FE, Tan A, Bonnard C, Boland GJ, Snippe H, Hibberd ML, Seielstad M.

    Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
    Talmud PJ, Drenos F, Shah S, Shah T, Palmen J, Verzilli C, Gaunt TR, Pallas J, Lovering R, Li K, Casas JP, Sofat R, Kumari M, Rodriguez S, Johnson T, Newhouse SJ, Dominiczak A, Samani NJ, Caulfield M, Sever P, Stanton A, Shields DC, Padmanabhan S, Melander O, Hastie C, Delles C, Ebrahim S, Marmot MG, Smith GD, Lawlor DA, Munroe PB, Day IN, Kivimaki M, Whittaker J, Humphries SE, Hingorani AD, ASCOT investigators, NORDIL investigators, BRIGHT Consortium.

    CD72 polymorphism associated with child-onset of idiopathic thrombocytopenic purpura in Chinese patients.
    Xu J, Lu S, Tao J, Zhou Z, Chen Z, Huang Y, Yang R, Xu J, Lu S, Tao J, Zhou Z, Chen Z, Huang Y, Yang R.

    CD72 polymorphisms associated with alternative splicing modify susceptibility to human systemic lupus erythematosus through epistatic interaction with FCGR2B.
    Hitomi Y, Tsuchiya N, Kawasaki A, Ohashi J, Suzuki T, Kyogoku C, Fukazawa T, Bejrachandra S, Siriboonrit U, Chandanayingyong D, Suthipinittharm P, Tsao BP, Hashimoto H, Honda Z, Tokunaga K, Hitomi Y, Tsuchiya N, Kawasaki A, Ohashi J, Suzuki T, Kyogoku C, Fukazawa T, Bejrachandra S, Siriboonrit U, Chandanayingyong D, Suthipinittharm P, Tsao BP, Hashimoto H, Honda Z, Tokunaga K.

    03/13/2008
    results indicated that the presence of CD72-*2 allele decreases risk for human systemic lupus erythematosus conferred by FCGR2B-232Thr, possibly by increasing the AS isoform of CD72

    CD72 polymorphisms associated with alternative splicing modify susceptibility to human systemic lupus erythematosus through epistatic interaction with FCGR2B.
    Hitomi Y, Tsuchiya N, Kawasaki A, Ohashi J, Suzuki T, Kyogoku C, Fukazawa T, Bejrachandra S, Siriboonrit U, Chandanayingyong D, Suthipinittharm P, Tsao BP, Hashimoto H, Honda Z, Tokunaga K, Hitomi Y, Tsuchiya N, Kawasaki A, Ohashi J, Suzuki T, Kyogoku C, Fukazawa T, Bejrachandra S, Siriboonrit U, Chandanayingyong D, Suthipinittharm P, Tsao BP, Hashimoto H, Honda Z, Tokunaga K.

    01/21/2010
    CD72 is a key molecule in regulating mature B cell differentiation; CD72 signaling reduces the expression of X-box binding protein 1 in B cells

    CD72-mediated suppression of human naive B cell differentiation by down-regulating X-box binding protein 1.
    Yamazaki T, Nagumo H, Hayashi T, Sugane K, Agematsu K.

    01/21/2010
    increased nucleotide mutation of CD72 mRNA accounts for the decreased expression level of CD72 in B cells, and it might be related to hyperactivity of B cells in patients with SLE

    Increased mutations of CD72 transcript in B-lymphocytes from adolescent patients with systemic lupus erythematosus.
    Kaneko U, Toyabe S, Hara M, Uchiyama M.

    01/21/2010
    firstprevious page of 1 nextlast