Targeting SIK3 to modulate hippocampal synaptic plasticity and cognitive function by regulating the transcription of HDAC4 in a mouse model of Alzheimer's disease.
Dai X, Lin A, Zhuang L, Zeng Q, Cai L, Wei Y, Liang H, Gao W, Zhang J, Chen X.,

Structural insights into the HDAC4-MEF2A-DNA complex and its implication in long-range transcriptional regulation.
Dai S, Guo L, Dey R, Guo M, Zhang X, Bates D, Cayford J, Jiang L, Wei H, Chen Z, Zhang Y, Chen L, Chen Y., Free PMC Article

ZIP4 upregulation aggravates nucleus pulposus cell degradation by promoting inflammation and oxidative stress by mediating the HDAC4-FoxO3a axis.
Shen M, Li K, Wang L, Feng L, Zhang X, Zhang H, Zhou H, Pei G., Free PMC Article

HDAC4 regulates the proliferation, migration, and invasion of trophoblasts in pre-eclampsia through the miR-134-5p/FOXM1 axis.
Xu Y, Kang X, Jiang H, Liu H, Wang W.

Association between circHIPK3/miR-378a-3p/HDAC4 axis and osteoporotic fractures: A comprehensive investigation.
Wang L, Sheng Z, Yao T.

Candidate Oligo Therapeutic Target, miR-330-3p, Induces Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer Cells via HDAC4.
Zhang M, Wang M, Jiang Z, Fu Z, Ma J, Gao S., Free PMC Article

LncRNA CASC11 upregulation promotes HDAC4 to alleviate oxidized low-density lipoprotein-induced injury of cardiac microvascular endothelial cells.
Hu K, Huang MJ, Ling S, Li YX, Cao XY, Chen YF, Lei JM, Fu WZ, Tan BF.

Silencing circular RNA hsa_circABCC1 inhibits osteosarcoma progression through down-regulating HDAC4 via sponging miR-591.
Wang K, Wang N, Liu J, Zhou J, Lei S, Yue H, Feng H, Feng K, Kang X.

WTAP-Mediated m6A RNA Methylation Regulates the Differentiation of Bone Marrow Mesenchymal Stem Cells via the miR-29b-3p/HDAC4 Axis.
Liu J, You Y, Sun Z, Zhang L, Li X, Dai Z, Ma J, Chen Y, Jiao G., Free PMC Article

Circulating HDAC4 reflects lipid profile, coronary stenosis and inflammation in coronary heart disease patients.
Guo Z, Wu Y, Feng Q, Wang C, Wang Z, Zhu Y, Lu X, Chen W, Yang Q, Huo Y.

HDAC4 depletion ameliorates IL-13-triggered inflammatory response and mucus production in nasal epithelial cells via activation of SIRT1/NF-κB signaling.
Xu H, Wang L, Chen H, Cai H., Free PMC Article

Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.
Wang T, Lu Z, Han T, Wang Y, Gan M, Wang JB., Free PMC Article

LncRNA MALAT1 promotes decidualization of endometrial stromal cells via sponging miR-498-3p and targeting histone deacetylase 4.
Shi L, Zhu L, Gu Q, Kong C, Liu X, Zhu Z.

Clinical role of serum histone deacetylase 4 measurement in acute ischemic stroke: Relation to disease risk, severity, and prognosis.
Wang M, Pang X, Lu H, Wang X., Free PMC Article

Circular RNA circPSAP functions as an efficient miR-331-3p sponge to regulate proliferation, apoptosis and bortezomib sensitivity of human multiple myeloma cells by upregulating HDAC4.
Ma H, Shen L, Yang H, Gong H, Du X.

Cytoplasmic HDAC4 regulates the membrane repair mechanism in Duchenne muscular dystrophy.
Renzini A, Marroncelli N, Cavioli G, Di Francescantonio S, Forcina L, Lambridis A, Di Giorgio E, Valente S, Mai A, Brancolini C, Giampietri C, Magenta A, De Santa F, Adamo S, Coletti D, Moresi V., Free PMC Article

Circular RNA circ_0008360 Inhibits the Proliferation, Migration, and Inflammation and Promotes Apoptosis of Fibroblast-Like Synoviocytes by Regulating miR-135b-5p/HDAC4 Axis in Rheumatoid Arthritis.
Hao J, Chen Y, Yu Y.

GAS5 regulates viability and apoptosis in TGF-β1-stimulated bronchial epithelial cells by regulating miR-217/HDAC4 axis.
Zhao S, Ning Y, Qin N, Ping N, Yu Y, Yin G.

Histone deacetylase 4 inhibits NF-κB activation by facilitating IκBα sumoylation.
Yang Q, Tang J, Xu C, Zhao H, Zhou Y, Wang Y, Yang M, Chen X, Chen J., Free PMC Article

miRNA-483-5p Targets HDCA4 to Regulate Renal Tubular Damage in Diabetic Nephropathy.
Liu L, Chen H, Yun J, Song L, Ma X, Luo S, Song Y.

HDAC4 degradation during senescence unleashes an epigenetic program driven by AP-1/p300 at selected enhancers and super-enhancers.
Di Giorgio E, Paluvai H, Dalla E, Ranzino L, Renzini A, Moresi V, Minisini M, Picco R, Brancolini C., Free PMC Article

Coupling HDAC4 with transcriptional factor MEF2D abrogates SPRY4-mediated suppression of ERK activation and elicits hepatocellular carcinoma drug resistance.
Ma Q, Xu Q, Zhao J, Zhang W, Wang Q, Fang J, Lu Z, Liu J, Ma L.

HDAC4 Knockdown Induces Preeclampsia Cell Autophagy and Apoptosis by miR-29b.
Du J, Ji Q, Dong L, Meng Y, Xin G.

Neddylation Regulates Class IIa and III Histone Deacetylases to Mediate Myoblast Differentiation.
Zhou H, Su H, Chen W., Free PMC Article

MiR-206 regulates the progression of osteoporosis via targeting HDAC4.
Lu Z, Wang D, Wang X, Zou J, Sun J, Bi Z., Free PMC Article