| Cumulative genetic score of KIAA0319 affects reading ability in Chinese children: moderation by parental education and mediation by rapid automatized naming. | Cumulative genetic score of KIAA0319 affects reading ability in Chinese children: moderation by parental education and mediation by rapid automatized naming.
Zhao J, Yang Q, Cheng C, Wang Z., Free PMC Article | 06/2/2023 |
| KIAA0319 influences cilia length, cell migration and mechanical cell-substrate interaction. | KIAA0319 influences cilia length, cell migration and mechanical cell-substrate interaction.
Diaz R, Kronenberg NM, Martinelli A, Liehm P, Riches AC, Gather MC, Paracchini S., Free PMC Article | 03/5/2022 |
| Results indicate that the polymorphisms rs4504469, rs2038137, rs2179515, rs3212236, rs6935076, rs9461045, rs2143340 and rs761100 have no association between the polymorphisms and dyslexia risk [Meta-analysis]. | Association between KIAA0319 SNPs and risk of dyslexia: a meta-analysis.
Deng KG, Zhao H, Zuo PX. | 12/14/2019 |
| Residues in strands B and E, and the BC loop of AAVR PKD2 interact directly with the AAV2 capsid. | Adeno-associated virus 2 bound to its cellular receptor AAVR.
Zhang R, Cao L, Cui M, Sun Z, Hu M, Zhang R, Stuart W, Zhao X, Yang Z, Li X, Sun Y, Li S, Ding W, Lou Z, Rao Z. | 08/3/2019 |
| By suggesting the presence of common biological processes underlying reading (dis)ability, these findings represent initial support for a generalist effect of the non-additive interdependence between READ1 and the KIAA0319 risk haplotype and can help in clinically assessing the individual risk for Developmental dyslexia. | The role of READ1 and KIAA0319 genetic variations in developmental dyslexia: testing main and interactive effects.
Trezzi V, Forni D, Giorda R, Villa M, Molteni M, Marino C, Mascheretti S. | 06/23/2018 |
| These findings suggest that DNA methylation patterns in the KIAA0319 promoter region might be associated with cognitive control processes that are necessary to perform well in the forced-attention conditions. | KIAA0319 promoter DNA methylation predicts dichotic listening performance in forced-attention conditions.
Schmitz J, Kumsta R, Moser D, Güntürkün O, Ocklenburg S. | 06/9/2018 |
| The study corroborates the importance of rs2038137-KIAA0319, and rs6935076-KIAA0319 in the aetiology of dyslexia. The relevance of rs2038137-KIAA0319, and rs6935076-KIAA0319 was further supported by the meta-analysis. | Association, characterisation and meta-analysis of SNPs linked to general reading ability in a German dyslexia case-control cohort.
Müller B, Wilcke A, Czepezauer I, Ahnert P, Boltze J, Kirsten H, LEGASCREEN consortium., Free PMC Article | 04/21/2018 |
| a meta-analysis of association studies involving KIAA0319 polymorphisms and Developmental Dyslexia risk, is reported. | Opposite Associations between Individual KIAA0319 Polymorphisms and Developmental Dyslexia Risk across Populations: A Stratified Meta-Analysis by the Study Population.
Shao S, Niu Y, Zhang X, Kong R, Wang J, Liu L, Luo X, Zhang J, Song R., Free PMC Article | 04/21/2018 |
| Missense variant in DYX2 gene is associated with reading disability. | Enrichment of putatively damaging rare variants in the DYX2 locus and the reading-related genes CCDC136 and FLNC.
Adams AK, Smith SD, Truong DT, Willcutt EG, Olson RK, DeFries JC, Pennington BF, Gruen JR., Free PMC Article | 12/9/2017 |
| Two SNPs in the KIAA0319 gene were nominally associated with rapid naming, and these associations were stable across different ages in longitudinal data set from the Dutch Dyslexia Program. | Association analysis of dyslexia candidate genes in a Dutch longitudinal sample.
Carrion-Castillo A, Maassen B, Franke B, Heister A, Naber M, van der Leij A, Francks C, Fisher SE., Free PMC Article | 08/12/2017 |
| Study establishes KIAA0319 as a novel player in axon growth and regeneration with the ability to repress the intrinsic growth potential of axons; describes a novel regulatory mechanism operating during peripheral nervous system and central nervous system axon growth, and offers novel targets for the development of effective therapies to promote axon regeneration | The Dyslexia-susceptibility Protein KIAA0319 Inhibits Axon Growth Through Smad2 Signaling.
Franquinho F, Nogueira-Rodrigues J, Duarte JM, Esteves SS, Carter-Su C, Monaco AP, Molnár Z, Velayos-Baeza A, Brites P, Sousa MM., Free PMC Article | 05/7/2017 |
| This study indicated that genetic polymorphisms of KIAA0319 are associated with an increased risk of DD in the Uyghur population. | KIAA0319 gene polymorphisms are associated with developmental dyslexia in Chinese Uyghur children.
Zhao H, Chen Y, Zhang BP, Zuo PX., Free PMC Article | 04/8/2017 |
| The KIAA0319 gene is associated with both reading ability and general cognition, but in different ways. The effect on IQ appears to occur earlier in development and is transient, whereas the effect of reading ability occurs later and is moderated by antenatal maternal stress. | Associations Between the KIAA0319 Dyslexia Susceptibility Gene Variants, Antenatal Maternal Stress, and Reading Ability in a Longitudinal Birth Cohort.
D'Souza S, Backhouse-Smith A, Thompson JM, Slykerman R, Marlow G, Wall C, Murphy R, Ferguson LR, Mitchell EA, Waldie KE. | 12/24/2016 |
| Markers in DYX2 genes KIAA0319 and FAM65B were associated with cortical thickness in the left developing orbitofrontal region and global fractional anisotropy, respectively. KIAA0319 and ACOT13 were suggestively associated with overall fractional anisotropy and left pars opercularis cortical thickness, respectively. | Dyslexia and language impairment associated genetic markers influence cortical thickness and white matter in typically developing children.
Eicher JD, Montgomery AM, Akshoomoff N, Amaral DG, Bloss CS, Libiger O, Schork NJ, Darst BF, Casey BJ, Chang L, Ernst T, Frazier J, Kaufmann WE, Keating B, Kenet T, Kennedy D, Mostofsky S, Murray SS, Sowell ER, Bartsch H, Kuperman JM, Brown TT, Hagler DJ Jr, Dale AM, Jernigan TL, Gruen JR, Pediatric Imaging Neurocognition Genetics Study., Free PMC Article | 12/17/2016 |
| These results indicate that KIAA0319L is the fourth of four candidate dyslexia susceptibility genes that is involved in neuronal migration, which supports the association of abnormal neuronal migration with developmental dyslexia. | Embryonic disruption of the candidate dyslexia susceptibility gene homolog Kiaa0319-like results in neuronal migration disorders.
Platt MP, Adler WT, Mehlhorn AJ, Johnson GC, Wright KA, Choi RT, Tsang WH, Poon MW, Yeung SY, Waye MM, Galaburda AM, Rosen GD., Free PMC Article | 11/7/2015 |
| the association of DCDC2 and KIAA0319 with Developmental dyslexia in Chinese population should be further validated | Association study of developmental dyslexia candidate genes DCDC2 and KIAA0319 in Chinese population.
Sun Y, Gao Y, Zhou Y, Chen H, Wang G, Xu J, Xia J, Huen MS, Siok WT, Jiang Y, Tan LH. | 08/29/2015 |
| our findings suggest that KIAA0319 is associated with a reading-related cognitive skill | A common haplotype of KIAA0319 contributes to the phonological awareness skill in Chinese children.
Lim CK, Wong AM, Ho CS, Waye MM., Free PMC Article | 04/11/2015 |
| KIAA0319 and ROBO1 genes, and developmental dyslexia (DD), related neuropsychological phenotypes and comorbid language and mathematical (dis)abilities in a large cohort of 493 Italian nuclear families ascertained through a proband with a diagnosis of DD. | KIAA0319 and ROBO1: evidence on association with reading and pleiotropic effects on language and mathematics abilities in developmental dyslexia.
Mascheretti S, Riva V, Giorda R, Beri S, Lanzoni LF, Cellino MR, Marino C. | 04/4/2015 |
| This study demonstrated the association of developmental dyslexia with rs4504469 of KIAA0319 and not with any single-nucleotide polymorphisms of DCDC2. | Analysis of genetic variants of dyslexia candidate genes KIAA0319 and DCDC2 in Indian population.
Venkatesh SK, Siddaiah A, Padakannaya P, Ramachandra NB. | 05/3/2014 |
| results suggested that the 931C > T variant in KIAA0319, but not the -3G > A in DYX1C1, was significantly associated with the risk of dyslexia | Genetic variant in KIAA0319, but not in DYX1C1, is associated with risk of dyslexia: an integrated meta-analysis.
Zou L, Chen W, Shao S, Sun Z, Zhong R, Shi J, Miao X, Song R. | 05/11/2013 |
| The results of this study found that KIAA0319 gene contained polymorphisms that were significantly associated with white matter volume in the left temporo-parietal region and that white matter volume influenced reading ability. | Three dyslexia susceptibility genes, DYX1C1, DCDC2, and KIAA0319, affect temporo-parietal white matter structure.
Darki F, Peyrard-Janvid M, Matsson H, Kere J, Klingberg T. | 03/2/2013 |
| Association study of a functional genetic variant in KIAA0319 in German dyslexics. | Association study of a functional genetic variant in KIAA0319 in German dyslexics.
Kirsten H, Wilcke A, Ligges C, Boltze J, Ahnert P. | 11/17/2012 |
| Mutations in cilia co-expressed DCDC2, DYX1C1 and KIAA0319 genes are associated with a cognitive neurological disorder, dyslexia. | Exploring the transcriptome of ciliated cells using in silico dissection of human tissues.
Ivliev AE, 't Hoen PA, van Roon-Mom WM, Peters DJ, Sergeeva MG., Free PMC Article | 09/15/2012 |
| The Kiaa0319 plays a role in neuronal migration during embryonic development, and that early interference with this gene results in an array of behavioral deficits including impairments in rapid auditory processing and simple spatial learning. | Neocortical disruption and behavioral impairments in rats following in utero RNAi of candidate dyslexia risk gene Kiaa0319.
Szalkowski CE, Fiondella CG, Galaburda AM, Rosen GD, Loturco JJ, Fitch RH., Free PMC Article | 09/15/2012 |
| The results of this study confirmed that both FOXP2 and KIAA0319/TTRAP/THEM2 genes play an important role in human language development, but probably through different cerebral pathways. | Genetic variants of FOXP2 and KIAA0319/TTRAP/THEM2 locus are associated with altered brain activation in distinct language-related regions.
Pinel P, Fauchereau F, Moreno A, Barbot A, Lathrop M, Zelenika D, Le Bihan D, Poline JB, Bourgeron T, Dehaene S., Free PMC Article | 03/10/2012 |