The circular RNA circSLC16A10 alleviates diabetic retinopathy by improving mitochondrial function via the miR-761-5p/MFN2 axis. | The circular RNA circSLC16A10 alleviates diabetic retinopathy by improving mitochondrial function via the miR-761-5p/MFN2 axis. Lu L, Ning Y, Gu F, Lin Z, Qin Y, Feng L, Tang M, Cao Y. | 09/3/2024 |
MFN2 suppresses the accumulation of lipid droplets and the progression of clear cell renal cell carcinoma. | MFN2 suppresses the accumulation of lipid droplets and the progression of clear cell renal cell carcinoma. Cai Z, Luo W, Wang H, Zhu R, Yuan Y, Zhan X, Xie M, Zhuang H, Chen H, Xu Y, Li X, Liu L, Xu G., Free PMC Article | 07/8/2024 |
lncRNA ZNF593-AS inhibits cardiac hypertrophy and myocardial remodeling by upregulating Mfn2 expression. | lncRNA ZNF593-AS inhibits cardiac hypertrophy and myocardial remodeling by upregulating Mfn2 expression. Nie X, Fan J, Wang Y, Xie R, Chen C, Li H, Wang DW. | 07/3/2024 |
Mitofusin-2 enhances cervical cancer progression through Wnt/beta-catenin signaling. | Mitofusin-2 enhances cervical cancer progression through Wnt/β-catenin signaling. Ahn SY., Free PMC Article | 05/24/2024 |
Declined circular RNA mitofusin 2 constrains the deterioration of Wilms tumor via modulating microRNA-372-3p/transforming growth factor-beta receptor type 2 axis. | Declined circular RNA mitofusin 2 constrains the deterioration of Wilms tumor via modulating microRNA-372-3p/transforming growth factor-β receptor type 2 axis. Xiao M, Pu X, Tong W, Xiao X. | 03/14/2024 |
Evaluation of the role of mitofusin-1 and mitofusin-2 in periodontal disease. | Evaluation of the role of mitofusin-1 and mitofusin-2 in periodontal disease. Kırmızıgül ÖA, Sabanci A, Dişli F, Yıldız S, Milward MR, Aral K. | 02/2/2024 |
MTCH2 cooperates with MFN2 and lysophosphatidic acid synthesis to sustain mitochondrial fusion. | MTCH2 cooperates with MFN2 and lysophosphatidic acid synthesis to sustain mitochondrial fusion. Goldman A, Mullokandov M, Zaltsman Y, Regev L, Levin-Zaidman S, Gross A., Free PMC Article | 01/29/2024 |
Clinicopathologic features of two unrelated autopsied patients with Charcot-Marie-Tooth disease carrying MFN2 gene mutation. | Clinicopathologic features of two unrelated autopsied patients with Charcot-Marie-Tooth disease carrying MFN2 gene mutation. Hayashi H, Saito R, Tanaka H, Hara N, Koide S, Yonemochi Y, Ozawa T, Hokari M, Toyoshima Y, Miyashita A, Onodera O, Okamoto K, Ikeuchi T, Nakajima T, Kakita A., Free PMC Article | 01/3/2024 |
CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy. | CMT2A-linked MFN2 mutation, T206I promotes mitochondrial hyperfusion and predisposes cells towards mitophagy. Das R, Maity S, Das P, Kamal IM, Chakrabarti S, Chakrabarti O. | 01/3/2024 |
Role of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease. | Role of mitochondrial fusion proteins MFN2 and OPA1 on lung cellular senescence in chronic obstructive pulmonary disease. Li C, Liu Q, Chang Q, Xie M, Weng J, Wang X, Li M, Chen J, Huang Y, Yang X, Wang K, Zhang N, Chung KF, Adcock IM, Zhang H, Li F., Free PMC Article | 01/3/2024 |
Homozygous Mutations in GDAP1 and MFN2 Genes Resulted in Autosomal Recessive Forms of Charcot-Marie-Tooth Disease in Consanguineous Pakistani Families. | Homozygous Mutations in GDAP1 and MFN2 Genes Resulted in Autosomal Recessive Forms of Charcot-Marie-Tooth Disease in Consanguineous Pakistani Families. Asif M, Chiou CC, Hussain MF, Hussain M, Sajid Z, Gulsher M, Raheem A, Khan A, Nasreen N, Kloczkowski A, Hassan M, Iqbal F, Chen CC., | 11/18/2023 |
DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress. | DIAPH1-MFN2 interaction regulates mitochondria-SR/ER contact and modulates ischemic/hypoxic stress. Yepuri G, Ramirez LM, Theophall GG, Reverdatto SV, Quadri N, Hasan SN, Bu L, Thiagarajan D, Wilson R, Díez RL, Gugger PF, Mangar K, Narula N, Katz SD, Zhou B, Li H, Stotland AB, Gottlieb RA, Schmidt AM, Shekhtman A, Ramasamy R., Free PMC Article | 11/3/2023 |
A human mitofusin 2 mutation can cause mitophagic cardiomyopathy. | A human mitofusin 2 mutation can cause mitophagic cardiomyopathy. Franco A, Li J, Kelly DP, Hershberger RE, Marian AJ, Lewis RM, Song M, Dang X, Schmidt AD, Mathyer ME, Edwards JR, Strong CG, Dorn GW., Free PMC Article | 11/3/2023 |
Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8[+] T cell metabolic fitness and function in tumors. | Mitochondria-ER contact mediated by MFN2-SERCA2 interaction supports CD8(+) T cell metabolic fitness and function in tumors. Yang JF, Xing X, Luo L, Zhou XW, Feng JX, Huang KB, Liu H, Jin S, Liu YN, Zhang SH, Pan YH, Yu B, Yang JY, Cao YL, Cao Y, Yang CY, Wang Y, Zhang Y, Li J, Xia X, Kang T, Xu RH, Lan P, Luo JH, Han H, Bai F, Gao S. | 09/28/2023 |
LRRK2 aggravates kidney injury through promoting MFN2 degradation and abnormal mitochondrial integrity. | LRRK2 aggravates kidney injury through promoting MFN2 degradation and abnormal mitochondrial integrity. Zhang S, Qian S, Liu H, Xu D, Xia W, Duan H, Wang C, Yu S, Chen Y, Ji P, Wang S, Cui X, Wang Y, Shen H., Free PMC Article | 09/13/2023 |
Mitofusin 1 overexpression rescues the abnormal mitochondrial dynamics caused by the Mitofusin 2 K357T mutation in vitro. | Mitofusin 1 overexpression rescues the abnormal mitochondrial dynamics caused by the Mitofusin 2 K357T mutation in vitro. Stavropoulos F, Georgiou E, Schiza N, Bell S, Baloh RH, Kleopa KA, Sargiannidou I. | 09/8/2023 |
The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases. | The Role of Mitochondrial Dynamics and Mitotic Fission in Regulating the Cell Cycle in Cancer and Pulmonary Arterial Hypertension: Implications for Dynamin-Related Protein 1 and Mitofusin2 in Hyperproliferative Diseases. Colpman P, Dasgupta A, Archer SL., Free PMC Article | 08/2/2023 |
Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria. | Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria. Naón D, Hernández-Alvarez MI, Shinjo S, Wieczor M, Ivanova S, Martins de Brito O, Quintana A, Hidalgo J, Palacín M, Aparicio P, Castellanos J, Lores L, Sebastián D, Fernández-Veledo S, Vendrell J, Joven J, Orozco M, Zorzano A, Scorrano L. | 07/10/2023 |
MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4. | MFN2 deficiency affects calcium homeostasis in lung adenocarcinoma cells via downregulation of UCP4. Zhang J, Pan L, Zhang Q, Zhao Y, Wang W, Lin N, Zhang S, Wu Q., Free PMC Article | 06/12/2023 |
Mitofusin-2: Functional switch between mitochondrial function and neurodegeneration. | Mitofusin-2: Functional switch between mitochondrial function and neurodegeneration. Kulkarni PG, Mohire VM, Bhaisa PK, Joshi MM, Puranik CM, Waghmare PP, Banerjee T. | 03/14/2023 |
Mitofusin 2 mutation drives cell proliferation in Charcot-Marie-Tooth 2A fibroblasts. | Mitofusin 2 mutation drives cell proliferation in Charcot-Marie-Tooth 2A fibroblasts. Zanfardino P, Longo G, Amati A, Morani F, Picardi E, Girolamo F, Pafundi M, Cox SN, Manzari C, Tullo A, Doccini S, Santorelli FM, Petruzzella V. | 01/21/2023 |
CircHIPK3 Regulates Vascular Smooth Muscle Cell Calcification Via the miR-106a-5p/MFN2 Axis. | CircHIPK3 Regulates Vascular Smooth Muscle Cell Calcification Via the miR-106a-5p/MFN2 Axis. Zhang WB, Qi YF, Xiao ZX, Chen H, Liu SH, Li ZZ, Zeng ZF, Wu HF. | 12/17/2022 |
A mitofusin 2/HIF1alpha axis sets a maturation checkpoint in regenerating skeletal muscle. | A mitofusin 2/HIF1α axis sets a maturation checkpoint in regenerating skeletal muscle. Wang X, Jia Y, Zhao J, Lesner NP, Menezes CJ, Shelton SD, Venigalla SSK, Xu J, Cai C, Mishra P., Free PMC Article | 12/10/2022 |
CMT2A-linked mitochondrial hyperfusion-driving mutant MFN2 perturbs ER-mitochondrial associations and Ca(2+) homeostasis. | CMT2A-linked mitochondrial hyperfusion-driving mutant MFN2 perturbs ER-mitochondrial associations and Ca(2+) homeostasis. Das R, Das S, Chakrabarti S, Chakrabarti O. | 11/12/2022 |
Mfn2-mediated mitochondrial fusion promotes autophagy and suppresses ovarian cancer progression by reducing ROS through AMPK/mTOR/ERK signaling. | Mfn2-mediated mitochondrial fusion promotes autophagy and suppresses ovarian cancer progression by reducing ROS through AMPK/mTOR/ERK signaling. Ashraf R, Kumar S. | 11/5/2022 |