Genome

Fibrobacter succinogenes Cellulolytic rumen bacterium Lineage: Bacteria[37515]; Fibrobacterota[37]; Fibrobacteria[24]; Fibrobacterales[13]; Fibrobacteraceae[8]; Fibrobacter[3]; Fibrobacter succinogenes[1]

Fibrobacter succinogenes. This bacterium is one of the three most predominant cellulolytic organisms in the rumen, the other two being Ruminococcus sp.. Since cellulose is one of the most abundant carbohydrates on the planet, this organism is, therefore, an important part of the global carbon biogeochemical cycle, converting the More...mass of fixed carbon generated by photosynthetic organisms back to products that eventually end up as carbon dioxide. Increasing cellulose degradation is an important goal in industrial processes. This organism is highly specialized for cellulose degradation, and is only capable of utilizing cellulose and cellulolytic degradation products as carbon sources. Access to cellulose is a rate-liming step in degradation, and the cellulolytic organisms have devised a number of mechanisms for improving access to this insoluble substrate, one of which is the production of surface-localized cellulases. The active enzymes are cell wall associated, but the presence of cellulosomes, large multiprotein cellulase complexes, has not been detected in this organism. Adherence is another method used to promote cellulose degradation, and this organism produces an extracellular matrix of glycoprotein glycocalyx which allows attachment to insoluble cellulose. In addition, the glycocalyx protects against protozoan attack of the bacterium as well as protease attack of the cellulase enzymes. Less...

Summary Sequence data:  genome assemblies: 49  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 3.15902  median protein count: 3042  median GC%: 49.5 Publications (limited to 20 most recent records) Whole-Genome Sequencing and Annotation of Fibrobacter succinogenes HC4, Isolated from the Horse Cecum. Froidurot A, et al. Microbiol Resour Announc 2022 Nov 17  Representative (genome information for reference and representative genomes) Reference genome:   Fibrobacter succinogenes subsp. succinogenes S85 Submitter: TIGR Morphology: Gram:Negative, Shape:Bacilli, Motility:No Environment: OxygenReq:Anaerobic, OptimumTemperature:37, TemperatureRange:Mesophilic, Habitat:HostAssociated Phenotype: Disease:None Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr - NC_017448.1 CP002158.1 3.84 48.0 3,087 9 58 3 3,170 13 Dendrogram (based on genomic BLAST)