Genome

Bacillus subtilis Model organism for prokaryotic cell differentiation and development Lineage: Bacteria[37515]; Bacillota[6135]; Bacilli[2619]; Bacillales[1727]; Bacillaceae[763]; Bacillus[125]; Bacillus subtilis group[15]; Bacillus subtilis[1]

Bacillus subtilis. This organism was one of the first bacteria studied, and was named Vibrio subtilis in 1835 and renamed Bacillus subtilis in 1872. It is one of the most well characterized bacterial organisms, and is a model system for cell differentiation and development. This soil bacterium can divide asymmetrically, producing More...an endospore that is resistant to environmental factors such as heat, acid, and salt, and which can persist in the environment for long periods of time. The endospore is formed at times of nutritional stress, allowing the organism to persist in the environment until conditions become favorable. Prior to the decision to produce the spore the bacterium might become motile, through the production of flagella, and also take up DNA from the environment through the competence system.The sporulation process is complex and involves the coordinated regulation of hundreds of genes in the genome. Environmental signals are sensed by bacterial two-component systems that initiate a phosphorelay that transfers phosphate to one of the key early transcriptional regulators, Spo0A. This initial step results in the coordinated asymmetric cellular division and endospore formation through multiple stages that produces a single spore from the mother cell. This cascade of gene regulation is intensively studied. Less...

Summary Sequence data:  genome assemblies: 920; sequence reads: 33  (See  Genome Assembly and Annotation report) Statistics:  median total length (Mb): 4.12194  median protein count: 4111  median GC%: 43.5 Publications (limited to 20 most recent records) The Complex GH32 Enzyme Orchestra from Priestia megaterium Holds the Key to Better Discriminate Sucrose-6-phosphate Hydrolases from Other β-Fructofuranosidases in Bacteria. Dobrange E, et al. J Agric Food Chem 2024 Jan 17 Cataloging the phylogenetic diversity of human bladder bacterial isolates. Du J, et al. Genome Biol 2024 Mar 21 Whole genome sequencing and the lignocellulose degradation potential of Bacillus subtilis RLI2019 isolated from the intestine of termites. Liu G, et al. Biotechnol Biofuels Bioprod 2023 Aug 19 Blautia parvula sp. nov., isolated from Japanese faecal samples. Miura T, et al. Int J Syst Evol Microbiol 2023 Nov Draft Genome Sequences of Nine Bacillus Strains and Two Weizmannia Strains Isolated from Live Dietary Supplements and a Cultured Food Product. Barnaba TJ, et al. Microbiol Resour Announc 2022 Jan 20 Bacillus symbiont drives alterations in intestinal microbiota and circulating metabolites of lepidopteran host. Li G, et al. Environ Microbiol 2022 Sep Draft Genome Sequences of 18 Streptococcus Strains Isolated from Live Dietary Supplements and Cultured Food Products. Barnaba TJ, et al. Microbiol Resour Announc 2022 Jun 16 γ-Polyglutamic Acid Production, Biocontrol, and Stress Tolerance: Multifunction of Bacillus subtilis A-5 and the Complete Genome Analysis. Bai N, et al. Int J Environ Res Public Health 2022 Jun 22 Antarctic Rahnella inusitata: A Producer of Cold-Stable β-Galactosidase Enzymes. Núñez-Montero K, et al. Int J Mol Sci 2021 Apr 16 Data on the genome of Bacillus subtilis A1- Midalam from beach soil. Pramod S, et al. Data Brief 2021 Dec Analysis of a bac operon-silenced strain suggests pleiotropic effects of bacilysin in Bacillus subtilis. Ertekin O, et al. J Microbiol 2020 Apr Bacillus subtilis EA-CB0575 genome reveals clues for plant growth promotion and potential for sustainable agriculture. Franco-Sierra ND, et al. Funct Integr Genomics 2020 Jul Genomic and Metabolomic Analysis of Antarctic Bacteria Revealed Culture and Elicitation Conditions for the Production of Antimicrobial Compounds. Núñez-Montero K, et al. Biomolecules 2020 Apr 27 Complete Genome Sequence of the Citrobacter freundii Type Strain. Wan KH, et al. Microbiol Resour Announc 2020 May 7 Temporal encoding of bacterial identity and traits in growth dynamics. Zhang C, et al. Proc Natl Acad Sci U S A 2020 Aug 18 Production of Highly Active Extracellular Amylase and Cellulase From Bacillus subtilis ZIM3 and a Recombinant Strain With a Potential Application in Tobacco Fermentation. Dai J, et al. Front Microbiol 2020 Experimental Evolution of Bacillus subtilis Reveals the Evolutionary Dynamics of Horizontal Gene Transfer and Suggests Adaptive and Neutral Effects. Slomka S, et al. Genetics 2020 Oct Whole-Genome Sequence of Bacillus subtilis WS1A, a Promising Fish Probiotic Strain Isolated from Marine Sponge of the Bay of Bengal. Rahman MM, et al. Microbiol Resour Announc 2020 Sep 24 Whole-Genome Shotgun Sequencing and Characterization of Probiotic Strain Clostridium butyricum UBCB 70 To Assess Its Safety. Sulthana A, et al. Microbiol Resour Announc 2019 Jan The Copy Number of the spoVA(2mob) Operon Determines Pressure Resistance of Bacillus Endospores. Li Z, et al. Appl Environ Microbiol 2019 Oct 1 More...  Representative (genome information for reference and representative genomes) Reference genome:   Bacillus subtilis subsp. subtilis str. 168 Submitter: BSNR Morphology: Gram:Positive, Shape:Bacilli, Motility:Yes Environment: OxygenReq:Facultative, OptimumTemperature:25-35, TemperatureRange:Mesophilic, Habitat:Terrestrial Type Name RefSeq INSDC Size (Mb) GC% Protein rRNA tRNA Other RNA Gene Pseudogene Chr - NC_000964.3 AL009126.3 4.22 43.5 4,237 30 86 95 4,536 88 Dendrogram (based on genomic BLAST) External Resources Complete Genome Sequence of Bacillus subtilis Bs-115