Focal deletions of a promoter tether activate the IRX3 oncogene in T-cell acute lymphoblastic leukemia [ATAC-Seq]

Nucleolar Pol II interactome reveals TBPL1, PAF1, and Pol I at intergenic rDNA drive rRNA biogenesis

Effects of vitamin D on VDR binding in THP-1 cells

Mediator kinase inhibition suppresses hyperactive interferon signaling in Down syndrome II

Pharmacological Repositioning of the transcription factor PU.1 [PRO-seq]

Pharmacological Repositioning of the transcription factor PU.1

TULIPs decorate the three-dimensional genome of PFA ependymoma

TFEB safeguards trophoblast syncytialization in humans and mice (ChIP-Seq)

TFEB safeguards trophoblast syncytialization in humans and mice

PGE2 alters chromatin through H2A.Zvariant enhancer nucleosome modification to promote hematopoietic stem cell fate (Mnase-Seq)

Immunotherapy-resistant acute lymphoblastic leukemia cells exhibit reduced CD19 and CD22 expression and BTK pathway dependency [ATAC-seq]

Phase separation mediated transcriptional activity of FOXK1 triggers glycolysis and facilitates renal fibrosis

Mezigdomide is effective alone and in combination with Menin inhibition in pre-clinical models of KMT2A-r and NPM1c AML

ChIP-seq analysis of HEK cells transfected with SARS-CoV-2 protein Orf8

ChIP-seq following CRISPRi perturbations to MYC enhancers in K562 cells

Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms [ChIP-seq]

IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells [ATAC-Seq]

IL-33 priming and antigenic stimulation synergistically promote the transcription of proinflammatory cytokine and chemokine genes in human skin mast cells

Effect of EZH2 and BET bromodomain inhibition, alone and combined, on NUT carcinoma gene expression

A genetically engineered mouse model (GEMM) of NUT carcinoma (RNA-Seq)