Mechanism of enhancing chemotherapy efficacy in pancreatic ductal adenocarcinoma with paricalcitol and hydroxychloroquine

Targeting CD206+ macrophages disrupts the establishment of a key anti-tumor immune axis [Bulk RNA-seq]

Decoupling the Biochemical and Mechanical Effects of Muscle Exercise on Motor Neurons with 2.5D Actuating Matrices [240614Ram_RNA-seq]

Tumor cell-specific Gpx4 deficiency reshaps tumor microenvironment and promotes NSCLC progression.

Ongoing replication stress tolerance and clonal T cell responses distinguish liver and lung recurrence and outcomes in pancreatic cancer

Fosl2 orchestrates chromatin accessibility to determine granulosa cells developmental trajectories [scRNA-Seq]

Crypt density and recruited enhancers underlie intestinal tumour initiation

Adaptive Biotechnologies TCRbeta sequencing of 174 primary and 42 metastatic pancreatic ductal adenocarcinoma tumor samples from FFPE curls and 215 matched blood plus 73 additional blood samples

Somatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output [ChIP-seq]

Somatic polyploidy supports biosynthesis and tissue function by increasing transcriptional output [RNA-seq]

Evolutionary fingerprint in rodent PD1 confers weakened activity and enhanced tumor immunity compared to human PD1

Adenine base editors induce off-target structure variations in mouse embryos and primary human T cells

scnasRNA-seq resolves in vivo single-cell RNA dynamics of immune cells during Salmonella infection [small intestine]

Prospective pharmacotyping of urothelial carcinoma organoids for drug sensitivity prediction – feasibility and real world experience

3D chromatin hubs as regulatory units of identity and survival in acute T-cell leukemia [scATAC-Seq]

Cross-species Single-cell Transcriptomics Reveals Neuronal Similarities and Heterogeneity in Amniote Pallium

Trans-generational adaptation to maternal climate through hormone transport in plants [scRNA-seq]

Strigolactones are involved in enhancing iron uptake in maize

Mutant IDH impairs chromatin binding by PDGFB to promote chromosome instability

Bone marrow endosteum houses Hedgehog-susceptible Dlx5-expressing osteoblast precursor cells [Fgfr3CE_Cxcl12GFP]