Investigating the effect of Daxx deletion on gene and repeat expression in embryonic stem cells and their differentiated neural derivatives

Genome-wide profiling of RNA Polymerase II, MITF and DDX21 occupancy in human A375 cells stably expressing either empty vector or HA-tagged PRL3.

Genome-wide profiling of transcription, H3K27me3 and RING1B occupancy in mouse ESCs following EZH1/2 inhibition

Transcriptional profiling by 4SU-seq in mouse ESCs and ESC-derived neural progenitor cells.

A new model for long-range chromatin reorganisation linked to enhancer activation [ChIP-chip]

Identification of a novel long-range enhancer driving Sonic Hedgehog expression in neural progenitor cells

Polycomb Underlies Transcriptional Heterogeneity in Lineage Priming of Embryonic Stem Cells [gene expression]

Polycomb Underlies Transcriptional Heterogeneity in Lineage Priming of Embryonic Stem Cells [ChIP-Seq and GRO-Seq]

Polycomb Underlies Transcriptional Heterogeneity in Lineage Priming of Embryonic Stem Cells

Gene expression analysis of mESCs following short-term inhibition with PD032, CHIRON, EPZ6438 and GSK-J4 both individually and in combination.

Polycomb Underlies Transcriptional Heterogeneity in Lineage Priming of Embryonic Stem Cells [ChIP-Seq]

Catalytically inactive Ring1B maintains near wildtype levels of gene expression in mESCs

Mouse ES cells expressing catalytically inactive Ring1B display impaired Ring1B and H3K27me3 deposition.

Loss of Ring1B catalytic activity causes a pronounced reduction in H3K27me3 deposition yet minimally disrupts the expression of target genes

Assessing inter- and intra-individual DNA methylation profiles in human brain samples

Chromatin decondensation is sufficient to alter nuclear organization in embryonic stem cells

Chip-chip from WT and Polycomb Component Knock Out Mouse ES cells for H2AZ, H3K27me3, EZH2 and Ring1B.