Pbx and Prdm1a transcription factors differentially regulate subsets of the fast skeletal muscle program in zebrafish

DUX4 binding to retroelements creates promoters that are active in FSHD muscle and testis.

DUX4-induced gene expression is the major molecular signature in FSHD skeletal muscle

Distinct activities of Myf5 and MyoD indicate sequential roles in skeletal muscle lineage specification and differentiation (RNA-Seq)

Distinct activities of Myf5 and MyoD indicate sequential roles in skeletal muscle lineage specification and differentiation

Model systems of DUX4 expression recapitulate the transcriptional profile of FSHD cells

Conservation and innovation in the DUX4-family gene network (RNA-seq)

DUX4-induced dsRNA and MYC mRNA Stabilization Activate Apoptotic Pathways in Human Cell Models of Facioscapulohumeral Dystrophy

Conservation and innovation in the DUX4-family gene network [MMH6 RNA-Seq]

MRI-informed muscle biopsies correlate MRI with pathology and DUX4 target gene expression in FSHD

DUX4-induced histone variants H3.X and H3.Y mark DUX4 target genes for expression (RNA-seq)

Longitudinal measures of RNA expression and disease activity in FSHD muscle biopsies

DUX4 orchestrates translational reprograming by broadly suppressing translation efficiency [RNA-seq]

MRI and gene signatures in facioscapulohumeral dystrophy muscle: implications for clinical trial design and mechanisms of disease progression

DUX4 activates germline genes, retroelements and immune-mediators: Implications for facioscapulohumeral dystrophy

Alternate exon switching establishes a tissue-specific transcription factor to mediate temporal activation of gene expression during differentiation

Distinct activities of Myf5 and MyoD indicate sequential roles in skeletal muscle lineage specification and differentiation (ChIP-Seq)

Small noncoding RNAs in FSHD2 muscle cells reveal both DUX4- and SMCHD1-specific signatures

DUX4 orchestrates translational reprograming by broadly suppressing translation efficiency [polysome-seq]

DUX4 orchestrates translational reprograming by broadly suppressing translation efficiency [Ribo-seq]