Microglia self-renewal comprises context-dependent random or clonal expansion.

RNAseq data from FACS-sorted microglia from mouse brain from control mice (uninjected) or LPS-injected mice in the context of A20 knockout

Mononuclear phagocytes locally specify and adapt their phenotype in the inflamed central nervous system, postimmunization expression data.

Constitutive and Tamoxifen inducible knockout of HDAC1 and HDAC2 in Microglia

RNAseq data from FACS-sorted CD45hi cells from mouse brain from control mice (uninjected) or LPS-injected mice in the context of A20 knockout

Mononuclear phagocytes locally specify and adapt their phenotype in the inflamed central nervous system, blood monocyte and brain microglia expression data

Mononuclear phagocytes locally specify and adapt their phenotype in the inflamed central nervous system, peak of disease expression data

Unique microglia expression profile in developing white matter.

smallRNA-sequencing reveals microRNAs as endogenous Toll-like receptor ligands causing neuroinflammation

RNA sequencing data of microglia isolated from brains of WT, Hexb-tdTomato, Hexb-CreERT2 and Hexb-KO mice. [Cre]

RNA sequencing data of microglia isolated from brains of WT, Hexb-tdTomato, Hexb-CreERT2 and Hexb-KO mice. [Hexb-KO]

RNA sequencing data of microglia isolated from brains of WT, Hexb-tdTomato, Hexb-CreERT2 and Hexb-KO mice. {Reporter]

Comparative gene expression profiling of cornea macrophages, retinal and brain microglia and bone marrow-derived monocytes

Microglia contribute to the propagation of Abeta pathology into healthy brain tissue