Genome-scale DNA methylation profiling of TEL/AML positive childhood acute lymphoblastic leukaemia

Utility of HM450 BeadArray on Mouse Samples

Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigatoing molecular mechanisms of drug resistance (expression)

Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigatoing molecular mechanisms of drug resistance (methylation)

Stability of gene expression and epigenetic profiles highlights the utility of patient-derived paediatric acute lymphoblastic leukaemia xenografts for investigatoing molecular mechanisms of drug resistance

Deep bisulfite amplicon sequencing and visualisation reveal diverse and heterogeneous DNA methylation patterns.

Exemplary multiplex bisulfite amplicon data used to demonstrate the utility of Methpat.

Genome-scale methylation assessment did not identify prognostic biomarkers in oral tongue carcinomas

DNA methylation profile of model breast cancer cell lines PMC42-ET and PMC42-LA

Deep sequencing and methylation profiling of both treated and untreated primary and recurrent tumours confirms the heterogeneous and dynamic nature of glioblastoma

Disease-specific transcriptomic changes induced by NFκB inhibition in idiopathic pulmonary fibrosis

Small-molecule inhibition of PRMT5 activates p53 in erythropoiesis through perturbation of mRNA processing, transport and protein translation