Non-coding genetic variation in GATA3 increases acute lymphoblastic leukemia risk through local and global changes in chromatin conformation

RIF1 is necessary to maintain the global epigenetic state in human cells.

Targeting P300/CBP reveals discrete regulation of transcription and chromatin accessibility by histone acetylation

Granulosa cell mevalonate pathway abnormalities contribute to oocyte meiotic defects and aneuploidy

MCM complexes are barriers that restrict cohesin-mediated loop extrusion

TAD Evolutionary and functional characterization reveals diversity in mammalian TAD boundary properties and function

SATB1 Regulates 3D Genome Architecture in T cells by Constraining Chromatin Interactions surrounding CTCF-binding sites

Integrative analysis of genomic structural variants in human leukemia

Integrated epigenomic analysis identifies structural alterations associated with oncogenic gene expression in liposarcoma

Investigating the role of telomere length in 3D spatiotemporal gene regulation in cardiomyocytes

Aberrant non-canonical NF-κB signalling reprograms the epigenome landscape to drive oncogenic transcriptomes in multiple myeloma

Control of cell identity and early neuronal fate commitment by the enhancer module of Integrator

A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival

Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription

Anti-cancer drugs curaxins target the 3D genome organization

YY1 regulates DNA-DNA interaction

Genomic instability is an early event driving chromatin organization and “escape” from oncogene-induced senescence

Sensitivity of cohesin-chromatin association to high salt treatment corroborates non-topological mode of loop extrusion

Biochemically distinct states of cohesin mediate formation of loop and TAD domains

3D chromatin organizations of human pancreatic cells reveal cell-type specific regulatory architectures of diabetes risk