Embryonic stem cell based system for the discovery and mapping of developmental transcriptional programs

Transcriptional mechanisms controlling direct motor neuron programming

A Cdx4-Sall4 regulatory module controls the transition from mesoderm formation to embryonic hematopoiesis

Co-regulated gene expression downstream of a single transcription factor controls the acquisition of corticospinal motor neuron identity

A multi-step transcriptional and chromatin cascade underlies motor neuron programming (transcription factor ChIP-seq)

Characterizing protein-DNA binding event subtypes in ChIP-exo data

Molecular basis of neuronal subtype bias introduced by proneural factors Ascl1 and Neurog2 (ATAC-seq)

Molecular basis of neuronal subtype bias introduced by proneural factors Ascl1 and Neurog2 (ChIP-seq)

Diversification of posterior Hox patterning by graded ability to engage inaccessible chromatin [ATAC-seq]

Diversification of posterior Hox patterning by graded ability to engage inaccessible chromatin [ChIP-seq]

Diversification of posterior Hox patterning by graded ability to engage inaccessible chromatin

Foxa2 and Pet1 direct and indirect synergy drive serotonergic neuronal differentiation [ATAC-Seq]

Foxa2 and Pet1 direct and indirect synergy drive serotonergic neuronal differentiation [ChIP-Seq]

Joint sequence and chromatin neural networks characterize the differential abilities of Forkhead transcription factors to engage inaccessible chromatin

DNA sequence context and the chromatin landscape differentiate sequence-specific transcription factor binding in the human malaria parasite, Plasmodium falciparum