Histone Deacetylase 1 (HDAC1) maintains the transcriptome of embryonic stem cells through regulating acetylation at crucial genomic sites [ATAC-seq]

Remodeling of Il4-Il13-Il5 locus underlies selective gene expression (ChIP-seq)

CTCF binding landscape is established by the epigenetic status of the nucleosome, well-positioned relative to CTCF motif orientation

Pooled CRISPR screens with joint single-nucleus chromatin accessibility and transcriptome profiling

Oct4 overexpression and suppression of Notch signaling synergistically induce neurogenic competence in mammalian Muller glia.

Retinoic acid and TGF-β orchestrate organ-specific programs of tissue-residency

YAP-Driven Malignant Reprogramming of Oral Epithelial Stem Cells, CUT&TAG sequencing for YAP, H3K27ac, and H3K27me3

YAP-Driven Malignant Reprogramming of Oral Epithelial Stem Cells, ATAC sequencing

Single-cell analysis of bidirectional reprogramming between early embryonic states reveals mechanisms of differential lineage plasticities [scATAC-seq]

Calorie restriction increases insulin sensitivity to promote beta cell homeostasis and longevity.

Single-cell profiling of remyelination in the LPC model

Chromodomain protein CDYL confers forebrain identity to human cortical organoids by inhibiting neuronatin [ChIP-seq]

Generation of cellular diversity through temporal patterning of radial glia during mouse corticogenesis

A multitargeting approach rewires cell identity in fusion-negative rhabdomyosarcoma

Single-cell multiome uncovers differences in glycogen metabolism underlying species-specific speed of development [scRNAseq and scATACseq]

Glucocorticoids induce a maladaptive epithelial stress response to aggravate acute kidney injury

Glucocorticoids induce a maladaptive epithelial stress response to aggravate acute kidney injury [ATAC]

Circadian Dysfunction in Skeletal Muscle Impairs Limb Perfusion and Muscle Regeneration in Peripheral Artery Disease [Myotube-ATACseq]

Synchronization of growth and self-organizing digit pattern by WNT signaling

Synchronization of growth and self-organizing digit pattern by WNT signaling [ChIPseq]