RNase H2, mutated in Aicardi‐Goutières syndrome, resolves co-transcriptional R-loops to prevent DNA breaks and inflammation.

Vigilin/HDLBP promotes translation of endoplasmic reticulum-targeted mRNAs (WT vs HDLBP Ribo-seq + RNA-seq)

Vigilin/HDLBP promotes translation of endoplasmic reticulum-targeted mRNAs (HDLBP PAR-CLIP)

HDLBP binds ER-targeted mRNAs by multivalent interactions to promote protein synthesis of transmembrane and secreted proteins

Chromosome conformation for wild type and clb5 clb6 strains arrested in meiotic prophase I

Chromosome conformation for wild type, eco1-aa, wpl1Δ and eco1-aa wpl1Δ strains arrested in meiotic prophase I

Eco1-dependent cohesin acetylation anchors chromatin loops and cohesion to define functional meiotic chromosome domains

CRISPR activation and interference screens decode stimulation responses in primary human T cells [CRISPRa Perturb-seq]

CRISPR activation and interference screens decode stimulation responses in primary human T cells [Supplemental CRISPR]

Transcriptional regulation and chromatin architecture maintenance are decoupled functions at the Sox2 locus.

Resident T Cell Repertoires

Measuring transcription factor binding and gene expression using barcoded self-reporting transposon calling cards and transcriptomes

MHC class II proteins mediate cross-species entry of bat influenza viruses