An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming

Overlapping and distinct functions of CstF64 and CstF64τ in mammalian mRNA 3’ processing

Integrative analyses of human reprogramming reveal dynamic nature of induced pluripotency

Highly parallel genome-wide expression profiling of individual cells using nanoliter droplets

Drop-Seq analysis of ERCC spike in capture

The menu of features that define primary microRNAs and enable de novo design of microRNA genes

Rocaglamide A converts RNA helicase eIF4A into a sequence-specific translational repressor

Molecular basis for cytoplasmic RNA surveillance by uridylation-triggered decay in Drosophila

Distinct roles for motif affinity, chromatin state, and co-regulatory motifs in PPARγ binding and enhancer activity

Thiol-linked alkylation for the metabolic sequencing of RNA

Regulation of m6A transcripts by the 3ʹ→5ʹ RNA helicase YTHDC2 is essential for a successful meiotic program in the mammalian germline

The Peril DNA locus acts as an in vivo enhancer for distal but not proximal genes

Determination of branch point (BP) usage by wild-type and mutant SF3B1 using a minigene library

A combination of transcription factors mediates inducible interchromosomal contacts

Systematic Analysis of Transcription Factors Binding to Noncoding Variants

Genome-wide CRISPR-Cas9 screen identifies druggable synthetic lethality between LSD1 and MTORC1 in MLL-translocated AML

Loss of CHD1 promotes chromatin dysregulation leading to heterogeneous mechanisms of resistance to hormone therapy in prostate cancer

Simultaneous measurement of DNA repair activities and mRNA abundance in single cells

Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer

Analysis of regulatory element evolution between human and mouse reveals a lack of cis-trans compensation