Epigenetic regulation of profibrotic macrophages in systemic sclerosis- associated interstitial lung disease

Stepwise chromatin and transcriptional acquisition of an intraepithelial lymphocyte program

Transcription Factor Protein Interactomes Reveal Genetic Determinants in Heart Disease

single-cell-RNA-sequencing and H3K9me3 occupancy of CD8+ T cells

Transcriptional and chromatin profiles of duodenum epithelium upon HNF4 loss in mice by RNA-seq and ChIP-seq

A neutropenia-associated transcription factor mutation differentially impacts target genes in the cell-states traversed during granulocyte specification and commitment

Identification of tissue regulatory T cell precursors in lymphoid organs

Dynamic transcriptional responses to injury of regenerative and non-regenerative cardiomyocytes revealed by single-nucleus RNA sequencing

Distinct Regulatory Programs Control the Latent Regenerative Potential of Dermal Fibroblasts during Wound Healing

Histone demethylase Lsd1 regulates multiple repressive gene programs during T cell development

Global genome decompaction leads to stochastic activation of gene expression as a first step toward fate commitment in human hematopoietic cells.

Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo

Bidirectional perisomatic inhibitory plasticity of a Fos neuronal network

HOTTIP reinforces CTCF-defined TAD boundaries by forming R-loops to drive Wnt/b-catenin target gene expression in AML leukemogenesis

Chemical-induced chromatin remodeling reprograms mouse ESCs to totipotent-like stem cells

Zebrafish tumors driven by overexpression of human IRF4

Skin regeneration is enabled in the absence of fibroblast inflammatory priming

Direct neuronal reprogramming by temporal identity factors

MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming

Occult polyclonality of preclinical pancreatic cancer models drives in vitro evolution.