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Platform GPL25480 Query DataSets for GPL25480
Status Public on Aug 22, 2018
Title Genometry L1000™ Expression Profiling
Technology type oligonucleotide beads
Distribution commercial
Organism Homo sapiens
Manufacturer Genometry, Inc.
Manufacture protocol amino-modified oligonucleotides are covalently attached to Luminex® MagPlex® Microspheres
 
Description L1000™ Expression Profiling is a high-throughput whole-genome gene-expression profiling assay based on the direct measurement of a reduced representation of the transcriptome and computational inference of the portion of the transcriptome not explicitly measured. The number of 'landmark' transcripts whose abundance is measured directly is nine hundred seventy eight (978). Eighty (80) additional invariant transcripts are also explicitly measured to enable scaling and normalization. Measurements of transcript abundance are made from crude cell lysates or purified total RNA in 384-well plate format with a combination of ligation-mediated amplification, optically-addressed microspheres, and flow cytometry. The inference model is trained on tens-of-thousands of public Affymetrix® GeneChip® gene-expression profiles. The resulting data are therefore denominated in the 22,268 (non-internal-control) features from the HG-U133A microarray. Landmark values are log-transformed, intra-sample scaled (against the invariant features), and intra-batch quantile normalized before the inference model is applied. A flag indicates whether a feature is measured ("LM") or inferred ("INF").
 
Web link http://genometry.com
Submission date Aug 21, 2018
Last update date Aug 22, 2018
Contact name Justin Lamb
Organization name Genometry, Inc.
Street address 37 Spinelli Place
City Cambridge
State/province MA
ZIP/Postal code 02138
Country USA
 
Samples (5902) GSM3363001, GSM3363002, GSM3363003, GSM3363004, GSM3363005, GSM3363006 
Series (17)
GSE119275 Expression-based drug screening of neural progenitor cells from individuals with schizophrenia [MSA101]
GSE119276 Expression-based drug screening of neural progenitor cells from individuals with schizophrenia [MSA102]
GSE119277 Expression-based drug screening of neural progenitor cells from individuals with schizophrenia [MSA103]

Data table header descriptions
ID Affymetrix probeset
FLAG measured ("LM") or inferred ("INF")
SEQUENCE gene-specific segment of ligation probes
SPOT_ID

Data table
ID FLAG SEQUENCE SPOT_ID
1007_s_at LM GCTTCTTCCTCCTCCATCACCTGAAACACTGGACCTGGGG 1007_s_at
121_at LM TGTGCTTCCTGCAGCTCACGCCCACCAGCTACTGAAGGGA 121_at
200024_at LM ATGCCTTCGAGATCATACACCTGCTCACAGGCGAGAACCC 200024_at
200045_at LM GGTGGTGCTGTTCTTTTCTGGTGGATTTAATGCTGACTCA 200045_at
200053_at LM TGCTATTAGAGCCCATCCTGGAGCCCCACCTCTGAACCAC 200053_at
200059_s_at LM ACAGCCCTCCTCTGCACTCCCACCTGACACACCAGGCGCT 200059_s_at
200060_s_at LM CGTTCATGGTGGTCTTTCAGGTTATCTTGGCAACATGTAC 200060_s_at
200071_at LM GGATGTGTGATGTTTATATGGGAGAACAAAAAGCTGATGT 200071_at
200078_s_at LM TCCAGAGTGAAGATGGGTGACTAGATGATATGTGTGGGTG 200078_s_at
200081_s_at LM CTGGGCCCCAAAAGAGCTAGCAGAATCCGCAAACTTTTCA 200081_s_at
200083_at LM CACCACTGCAACATATAGACCTGAGTGCTATTGTATTTTG 200083_at
200602_at LM TCATTGCTTATGACATGATCGCTTTCTACACTGTATTACA 200602_at
200614_at LM ACAACACTAATCAGCACATCGTACACTGGATTGCAGTGCT 200614_at
200617_at LM TTTCCCATCCTCTCTCTGTGGAGGCCAAACCAACTCTTTG 200617_at
200621_at LM AGGCATGGGCTGTACCCAAGCTGATTTCTCATCTGGTCAA 200621_at
200622_x_at LM TATCACCACCAAGGAGTTGGGGACAGTGATGAGATCCCTG 200622_x_at
200636_s_at LM GTCCTTATTATCCCAGCTTGCTGAGGGGCAGGGAGAGCGC 200636_s_at
200666_s_at LM CTCTGTATAGGGCCATAATGGAATTCTGAAGAAATCTTGG 200666_s_at
200670_at LM AGTTTGCTTCTGTAAGCAACGGGAACACCTGCTGAGGGGG 200670_at
200678_x_at LM CCTGTCAGAAGGGGGTTGTGGCAAAAGCCACATTACAAGC 200678_x_at

Total number of rows: 22268

Table truncated, full table size 621 Kbytes.




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