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| Status |
Public on Jul 18, 2017 |
| Title |
Arginine-dependent gene regulation in Streptococcus gordonii ahrC regulator knockout |
| Platform organism |
Streptococcus gordonii |
| Sample organism |
Streptococcus gordonii str. Challis |
| Experiment type |
Expression profiling by array
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| Summary |
We have previously shown that responses of the oral bacterium Streptococcus gordonii to arginine are co-ordinated by three paralogous regulators: ArcR, ArgR and AhrC. This set of experiments was designed to assess the effects of the AhrC gene regulator on global gene expression in Streptococcus gordonii under high arginine or following a shift to no arginine.
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| Overall design |
Single colour microarrays were used to measure gene expression in four biological replicates of S. gordonii cells cultured, with and without arginine restriction. One replicate of 'arg+' was identified as an outlier and was not processed for normalised data. The raw data text file for this data set (US92200305_254184610003_S01_GE1_107_Sep09_1_2.txt) has been included in the supplementary files.
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| Contributor(s) |
Jakubovics NS, Casement J |
| Citation missing |
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| |
| Submission date |
Jul 17, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Nicholas S Jakubovics |
| E-mail(s) |
nick.jakubovics@ncl.ac.uk
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| Organization name |
Newcastle University
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| Department |
School of Dental Sciences
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| Lab |
Oral Biology
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| Street address |
Framlington Place
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| City |
Newcastle upon Tyne |
| ZIP/Postal code |
NE2 4BW |
| Country |
United Kingdom |
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| Platforms (1) |
| GPL17786 |
Agilent-041846 Streptococcus gordonii |
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| Samples (8)
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| This SubSeries is part of SuperSeries: |
| GSE101509 |
Effects of the ArcR gene regulator on global gene expression in Streptococcus gordonii under high arginine or following a shift to no arginine |
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| Relations |
| BioProject |
PRJNA394703 |
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