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| Status |
Public on Feb 28, 2018 |
| Title |
Chip-chip from human epidermis with H3ac |
| Organism |
Homo sapiens |
| Experiment type |
Genome binding/occupancy profiling by array
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| Summary |
The UV radiation induced epigenetic changes play an important role in photoaging, but experimental evidence of histone modification to support this perspective has been scarce.
Analyse the histone H3 acetylation pattern in sun-exposed and non-exposed skin by ChIP-chip. 227 genes displayed significant histone H3 hyperacetylation and 81 genes displayed significant histone H3 hypoacetylation in sun-exposed skins.
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| Overall design |
ChIP-chip assay with anti-acetyl-histone H3 antibody in sun-exposed Pool (combining six skin samples from the outer forearm) and non-exposed Pool (combining six skin samples from the buttock)
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| Contributor(s) |
Ding S, Liang G |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Oct 10, 2017 |
| Last update date |
Jul 25, 2021 |
| Contact name |
Shu Ding |
| Organization name |
The Third Xiangya Hospital
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| Street address |
Tongzipo street 138#
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| City |
changsha |
| State/province |
hunan |
| ZIP/Postal code |
410000 |
| Country |
China |
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| Platforms (1) |
| GPL15448 |
NimbleGen Human ChIP-chip 3x720K RefSeq Promoter Arrays [100718_HG18_Refseq_Prom_ChIP] |
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| Samples (2) |
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| Relations |
| BioProject |
PRJNA413782 |
