GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
Series GSE106264 Query DataSets for GSE106264
Status Public on Jan 17, 2018
Title single-cell-RNA-sequencing analysis of naive and Listeria monocytogenes-specific CD8+ T cells
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary The histone methyltransferase Suv39h1 silences transcriptional programs during CD8+-T cell differentiation
The study explores the role of gene silencing by Suv39h1, a histone methyltransferase, that plays a critical role in heterochromatin dynamics.
Overall design Naïve littermate and Suv39h1-KO CD8+ T cells, and day 7 p.i. Kb-OVA+ CD8+ T cells (from Listeria m.-OVA infected mice), were isolated by FACS. scRNA-seq was performed according to 10X Genomics technology. Both biological (Rep) and technical (tech) replicates were processed.
Contributor(s) Gueguen P, Bohec M, Baulande S, Goudot C, Amigorena S
Citation(s) 29326266
Submission date Oct 27, 2017
Last update date May 15, 2019
Contact name Luigia Pace
Organization name Institut Curie
Street address 26 rue d'Ulm
City Paris
ZIP/Postal code 75005
Country France
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (8)
GSM2833284 Naive CD8+ T cells WT, rep1
GSM2833285 Naive CD8+ T Suv39h1-KO, rep1
GSM2833286 kb-OVA+ CD8+ T cells WT, rep1
This SubSeries is part of SuperSeries:
GSE106268 single-cell-RNA-sequencing and H3K9me3 occupancy of CD8+ T cells
BioProject PRJNA416096
SRA SRP122504

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE106264_RAW.tar 20.8 Mb (http)(custom) TAR (of H5)
SRA Run SelectorHelp
Raw data are available in SRA
Processed data are available on Series record

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap