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Series GSE107537 Query DataSets for GSE107537
Status Public on May 08, 2018
Title The effect of simulated night shift work on the circadian regulation of the human transcriptome
Organism Homo sapiens
Experiment type Expression profiling by array
Summary Eight healthy human subjects were enrolled in a 6-day simulated shift work protocol. Blood samples were collected during the two 24-hour measurement periods. Blood samples were collected every 4 hours during both measurement periods. Subjects entered the lab on Day 1. At the start of Day 2, the first 24-hour measurement period was started. Subjects slept according to their habitual sleep/wake schedule, followed by a 16-hour constant posture procedure. On days 3-6, the sleep period was delayed by 10 hours. Following the third night on this schedule, subjects underwent another 24-hour measurement period. During both measurement periods, 7 blood samples were collected and PBMCs were isolated. mRNA was extracted, labelled, and hybridized to microarrays.
 
Overall design A total of 103 samples were collected from 8 subjects spread across two 24-hour measurement periods
 
Contributor(s) Kervezee L, Cuesta M, Cermakian N, Boivin DB
Citation(s) 29735673
Submission date Nov 30, 2017
Last update date Jan 31, 2019
Contact name Laura Kervezee
E-mail(s) laura.kervezee@douglas.mcgill.ca
Organization name McGill University
Department Douglas Mental Health University Institute
Street address 6875 LaSalle Boulevard
City Montreal
State/province Quebec
ZIP/Postal code H4H 1R3
Country Canada
 
Platforms (1)
GPL24324 [Clariom_S_Human_HT] Affymetrix Clariom S Assay HT, Human (Includes Pico Assay)
Samples (103)
GSM2870703 PBMC_DayOrientedSchedule_RelTime_0.5_Subject_T14
GSM2870704 PBMC_DayOrientedSchedule_RelTime_8.8_Subject_T14
GSM2870705 PBMC_DayOrientedSchedule_RelTime_13.2_Subject_T14
Relations
BioProject PRJNA420581

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Supplementary file Size Download File type/resource
GSE107537_RAW.tar 109.9 Mb (http)(custom) TAR (of CEL)
Processed data included within Sample table
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