NCBI Logo
GEO Logo
   NCBI > GEO > Accession DisplayHelp Not logged in | LoginHelp
GEO help: Mouse over screen elements for information.
          Go
Series GSE107839 Query DataSets for GSE107839
Status Public on Nov 28, 2018
Title All-RNA-seq data used in "Genetic resistance to DEHP-induced transgenerational endocrine disruption"
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary We Investigate the persistence of negative impacts on sperm parameters for more than one generation in C57BL/6J and in strain FVB/N subjected to prenatal exposure to di(2-ethylexyl)phthalate (DEHP) using in utero exposures followed by Computer-Aided Sperm Analysis (CASA) sampling and all-RNA-seq analysis of germ cells transcripts.
 
Overall design Pairwise comparisons and hierarchical clustering of: 1) 5 mouse C57BL/6J of the first generation that were exposed in utero to corn oil vehicle (C57.CTL.F1), 2) 5 mouse C57BL/6J of the first generation that were exposed in utero to DEHP (C57.D300.F1), 3) 5 mouse C57BL/6J of the second generation (C57.D300.2), 4) 5 mouse FVB/N of the first generation that were exposed in utero to corn oil vehicle (FVB.CTL.F1), 5) 5 mouse FVB/N of the first generation that were exposed in utero to DEHP (FVB.D300.F1).
 
Contributor(s) Stenz L, Rahban R, Prados J, Nef S, Paoloni-Giacobino A
Citation(s) 31181066
Ludwig Stenz, Rita Rahban, Julien Prados, Serge Nef, and Ariane Paoloni-Giacobino. Genetic resistance to DEHP-induced transgenerational endocrine disruption. bioRxiv 474155; doi:10.1101/474155.
Submission date Dec 08, 2017
Last update date Jun 24, 2019
Contact name Ludwig Stenz
E-mail(s) ludwig.stenz@unige.ch
Phone +41223795036
Organization name University of Geneva
Department Department of Genetic Medecine and Development
Lab Giacobino
Street address Rue Michel-Servet 1
City Geneva
ZIP/Postal code CH-1211 Genève 4
Country Switzerland
 
Platforms (1)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
Samples (25)
GSM2881401 C57_D300_F1_1 [re-analysis]
GSM2881402 C57_D300_F1_2 [re-analysis]
GSM2881403 C57_D300_F1_3 [re-analysis]
Relations
BioProject PRJNA421660
SRA SRP126386

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE107839_gene_exp.diff.gz 8.9 Mb (ftp)(http) DIFF
GSE107839_genes.count_tracking.txt.gz 1.3 Mb (ftp)(http) TXT
SRA Run SelectorHelp
Processed data are available on Series record
Raw data are available in SRA

| NLM | NIH | GEO Help | Disclaimer | Accessibility |
NCBI Home NCBI Search NCBI SiteMap