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Series GSE108330 Query DataSets for GSE108330
Status Public on Apr 02, 2019
Title Next Generation Sequencing Facilitates Quantitative Analysis of mRNA lifetime of Wild Type and Mettl3-/- mice
Organism Mus musculus
Experiment type Expression profiling by high throughput sequencing
Summary Considering m6A modification in mRNA was reported to be intensively correlated with RNA decay, for example, T cells and neurone cells. We wondered whether deleting Mettl3, the main catalzing enzyme, affect the RNA stability of mouse dendritic cells.
Overall design Two sets representing WT and KO dendritic cells were analyzed, each set contains three samples indicating three different treatment with Actinomycotoxin D for 0, 3, or 6h. No replicate was included.
Contributor(s) Cao X, Wang H, Hu X
Citation(s) 31015515
Submission date Dec 20, 2017
Last update date May 01, 2019
Contact name Huamin Wang
Phone +8618017766823
Organization name Peking Union Medical College, Chinese Academy of Medical Sciences,
Department Department of Immunology
Street address Three N0. 5 dongdan street, Dongcheng District, Beijing
City Beijing, China
ZIP/Postal code 100730
Country China
Platforms (1)
GPL21493 Illumina HiSeq 3000 (Mus musculus)
Samples (6)
GSM2895430 KO-D2-0h lifetime
GSM2895431 KO-D2-3h lifetime
GSM2895432 KO-D2-6h lifetime
This SubSeries is part of SuperSeries:
GSE108333 Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation
BioProject PRJNA423189
SRA SRP127230

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Supplementary file Size Download File type/resource
GSE108330_lifetime.xls.gz 1.8 Mb (ftp)(http) XLS
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Raw data are available in SRA
Processed data are available on Series record

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