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Series GSE108331 Query DataSets for GSE108331
Status Public on Apr 02, 2019
Title Next Generation Sequencing Facilitates Quantitative Analysis of mRNA translation efficiency of Wild Type and Mettl3-/- mice
Organism Mus musculus
Experiment type Other
Summary Considering m6A modification in mRNA was reported to be intensively corelated with RNA metabolism like RNA decay and RNA translation, we wonderd whether deleting Mettl3, the main catalzing enzyme, affect the RNA translation efficiency of mouse dendritic cells.
Overall design Two sets representing WT and KO dendritic cells were analyzed, each set contains sucrose gradient centrifuged sample and input indicating. No replicate was incluced.
Contributor(s) Cao X, Wang H, Hu X
Citation(s) 31015515
Submission date Dec 20, 2017
Last update date May 01, 2019
Contact name Huamin Wang
Phone +8618017766823
Organization name Peking Union Medical College, Chinese Academy of Medical Sciences,
Department Department of Immunology
Street address Three N0. 5 dongdan street, Dongcheng District, Beijing
City Beijing, China
ZIP/Postal code 100730
Country China
Platforms (2)
GPL17021 Illumina HiSeq 2500 (Mus musculus)
GPL21493 Illumina HiSeq 3000 (Mus musculus)
Samples (8)
GSM2895436 KO-ribosome profiling
GSM2895437 KO-ribosome profiling input
GSM2895438 WT-ribosome profiling
This SubSeries is part of SuperSeries:
GSE108333 Mettl3-mediated mRNA m6A methylation promotes dendritic cell activation
BioProject PRJNA423188
SRA SRP127229

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Supplementary file Size Download File type/resource
GSE108331_ribosome_profiling_processed_data.xls.gz 2.1 Mb (ftp)(http) XLS
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Raw data are available in SRA
Processed data are available on Series record

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