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Series GSE108516 Query DataSets for GSE108516
Status Public on Dec 01, 2023
Title Targeting of the YAP/SMAD molecular circuit inhibits a TGFb1-induced myofibroblast phenotype
Organism Homo sapiens
Experiment type Genome binding/occupancy profiling by high throughput sequencing
Summary The goal of this study was to elucidate the genomic occupancy of YAP in repsonse to transforming growth factor beta (TGFb) 1 in primary human dermal fibroblasts, through ChIP sequencing.
Overall design Genome binding/occupancy profiling of YAP in response to TGFb1, by high throughput sequencing. Two independent replicates of both unstimulated and TGFb1 stimulated cells were analyzed.
Contributor(s) Piersma B, Gjaltema RA, Boersema M, Bank RA
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Submission date Dec 26, 2017
Last update date Dec 01, 2023
Contact name Bram Piersma
Organization name University Medical Center Groningen
Department Pathology and Medical Biology
Street address Hanzeplein 1
City Groningen
State/province Groningen
ZIP/Postal code 9713GZ
Country Netherlands
Platforms (1)
GPL21697 NextSeq 550 (Homo sapiens)
Samples (5)
GSM2902657 HDF_Input
GSM2902658 HDF_TGFb1_YAP_Rep1
GSM2902659 HDF_TGFb1_YAP_Rep2
BioProject PRJNA427538
SRA SRP127543

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Supplementary file Size Download File type/resource
GSE108516_HDF_TGFb1_YAP_merged.bigwig 270.7 Mb (ftp)(http) BIGWIG
GSE108516_HDF_untreated_YAP_merged.bigwig 228.3 Mb (ftp)(http) BIGWIG
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Raw data are available in SRA
Processed data are available on Series record

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