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Series GSE109765 Query DataSets for GSE109765
Status Public on Apr 14, 2020
Title The Transgenerational Effects of Prenatal Synthetic Glucocorticoids on the Hippocampus Cortex
Organism Cavia porcellus
Experiment type Expression profiling by high throughput sequencing
Methylation profiling by high throughput sequencing
Summary First generation animals (F1) were exposed to multiple courses of synthetic glucocorticoids in utero. Animals were then bred to produce second (F2) and third (F3) generation offspring. These animals underwent behavioural assessmenets before sacrifice. In this experiment the prefrontal cortex for F1, F2, and F3 female animals, as well as F1 males (Control and sGC) have been extracted via micro-punch and RNA has been extracted.
Overall design Methylation Analyses: F1: Control N=6, sGC N=6; F2: Control N=6, sGC N=6; F3: Control N=7, sGC N=5; RNA-Seq Analyses: F1: Control N=6, sGC N=5; F2: Control N=6, sGC N=6; F3: Control N=6, sGC N=7
Contributor(s) Constantinof A, Boureau L, Moisiadis VG, Szyf M, Matthews SG
Citation(s) 31796763
Submission date Jan 29, 2018
Last update date Apr 14, 2020
Contact name Stephen Matthews
Organization name University of Toronto
Street address 1 King's College Circle
City Toronto
State/province Ontario
ZIP/Postal code M5S1A8
Country Canada
Platforms (1)
GPL22346 Illumina HiSeq 2500 (Cavia porcellus)
Samples (72)
GSM2966855 F1_Beta1_SGM2
GSM2966856 F1_Beta2_SGM3
GSM2966857 F1_Beta3_SGM6
BioProject PRJNA431992
SRA SRP131653

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SOFT formatted family file(s) SOFTHelp
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Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE109765_F1_HPC_Processed_data.txt.gz 667.1 Kb (ftp)(http) TXT
GSE109765_F1_HPC_SNR_Meth_processed_data.txt.gz 2.2 Mb (ftp)(http) TXT
GSE109765_F1window100_Meth_v85_processed_data.txt.gz 1.6 Mb (ftp)(http) TXT
GSE109765_F2_HPC_100bpv85_Meth_processed_data.txt.gz 1.4 Mb (ftp)(http) TXT
GSE109765_F2_HPC_Processed_data.txt.gz 652.0 Kb (ftp)(http) TXT
GSE109765_F2_HPC_SNR_Meth_processed_data.txt.gz 1.2 Mb (ftp)(http) TXT
GSE109765_F3_HPC_Processed_data.txt.gz 709.1 Kb (ftp)(http) TXT
GSE109765_F3_HPC_SNR_processed_data.txt.gz 1.7 Mb (ftp)(http) TXT
GSE109765_F3window100_Meth_v85_processed_data.txt.gz 1.4 Mb (ftp)(http) TXT
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Raw data are available in SRA
Processed data are available on Series record

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