|
| Status |
Public on Mar 12, 2018 |
| Title |
The cold shock response of Bacillus subtilis analyzed by RNA-sequencing: YplP regulates pyruvate transport at low temperatures |
| Organism |
Bacillus subtilis |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
The cold shock response of B. subtilis was defined after 0.5 hr and 2 hr cold shock using RNA sequencing. We identified novel RNAs (including non-coding RNAs) that play a role during growth at low temperatures. Deletion of the cold induced protein YplP results in a cold sensitive phenotype, and a comparative RNA sequencing analysis suggests that YplP induces pftAB expression after prolonged incubation at low temperatures, thereby optimizing pyruvate transport under cold shock conditions.
|
| |
|
| Overall design |
2 conditions, 2 strains, 2 timepoints
|
| |
|
| Contributor(s) |
van den Esker MH, Kuipers OP, de Jong A |
| Citation missing |
Has this study been published? Please login to update or notify GEO. |
| |
| Submission date |
Mar 08, 2018 |
| Last update date |
Mar 12, 2018 |
| Contact name |
Anne de Jong |
| E-mail(s) |
anne.de.jong@rug.nl
|
| Phone |
+31 50 363 2047
|
| Organization name |
university of Groningen
|
| Department |
Molecular Genetics
|
| Street address |
Nijenborgh 7
|
| City |
Groningen |
| ZIP/Postal code |
9747 AG |
| Country |
Netherlands |
| |
|
| Platforms (1) |
| GPL23851 |
Ion Torrent Proton (Bacillus subtilis) |
|
| Samples (9)
|
|
| Relations |
| BioProject |
PRJNA437458 |
| SRA |
SRP134186 |
Less...
More...