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Series GSE111670 Query DataSets for GSE111670
Status Public on Mar 13, 2018
Title The expression profiles of circRNAs in hippocampus from mice with prenatal glyphosate exposure
Organism Mus musculus
Experiment type Non-coding RNA profiling by array
Summary In this study, the circRNAs expression pattern in hippocampus of postnatal day (PND) 28 mice offsprings which were exposured by glyphosate-based herbicide (GBH) during pregnancy and lactation was investigated.
CircRNA microarray had detected 330 upregulated and 333 downregulated miRNAs in the PND28 mice offsprings' hippocampus
 
Overall design In this study, the isolated total RNA taken from two pooled samples of two groups, was used to acquire expression profiles, and the result shows 663 differentially-expressed circRNAs, some of them are known to be involved in brain development or the pathogenesis of neurodevelopmental disorders, indicate that dysregulated expression of circRNAs may be involved in the mechanism of glyphosate-induced neurotoxicity.
 
Contributor(s) Ji H, Yu N, Fan X
Citation(s) 29705695
Submission date Mar 12, 2018
Last update date Jun 21, 2018
Contact name Hua Ji
E-mail(s) jihua@hmc.edu.cn
Organization name Hangzhou medical college
Department Department of Basic Medicine
Street address No.481 Bingwen road
City HangZhou City
State/province Zhejiang
ZIP/Postal code 310053
Country China
 
Platforms (1)
GPL21826 074663 Arraystar Mouse CircRNA microarray V2
Samples (2)
GSM3036905 hippocampus, control
GSM3036906 hippocampus, glyphosate-based herbicide (GBH) exposure
Relations
BioProject PRJNA437842

Download family Format
SOFT formatted family file(s) SOFTHelp
MINiML formatted family file(s) MINiMLHelp
Series Matrix File(s) TXTHelp

Supplementary file Size Download File type/resource
GSE111670_RAW.tar 1.4 Mb (http)(custom) TAR (of TXT)
Processed data included within Sample table

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