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| Status |
Public on Nov 05, 2024 |
| Title |
Characterization of innate immune responses to AS03 adjuvanted H5N1 vaccine compared to non-adjuvanted H5N1 vaccine. |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
|
| Summary |
The primary objective is to compare multiplex immune response signatures following two (primary and a boost) vaccinations with the GSK AS03 adjuvanted H5N1 influenza vaccine or the non-adjuvanted form of the H5N1 influenza vaccine
at the 3.75 mcg dose and given 21 days apart and identify differences in very early innate immune responses. These immune signatures will also be correlated with the clinical observations especially safety related local and systemic events.
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| |
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| Overall design |
Immune response signatures following two (primary and a boost) vaccinations with the GSK AS03 adjuvanted H5N1 influenza vaccine or the non-adjuvanted form of the H5N1 influenza vaccine
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| Contributor(s) |
Cheung F |
| Citation(s) |
39235945 |
| |
| Submission date |
Mar 23, 2018 |
| Last update date |
Nov 06, 2024 |
| Contact name |
Foo Cheung |
| E-mail(s) |
foo.cheung@nih.gov
|
| Organization name |
NIH
|
| Street address |
Bethesda
|
| City |
Bethesda |
| ZIP/Postal code |
20851 |
| Country |
USA |
| |
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| Platforms (1) |
| GPL17692 |
[HuGene-2_1-st] Affymetrix Human Gene 2.1 ST Array [transcript (gene) version] |
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| Samples (898)
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| Relations |
| BioProject |
PRJNA445554 |
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