|
| Status |
Public on Oct 06, 2020 |
| Title |
Inhibition of CXCR1/2 in human colitis-derived pluripotent stem cell intestinal organoids attenuates the inflammatory phenotype |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by high throughput sequencing
|
| Summary |
We report the results of RNA-Seq on iPSCs, Definitive Endoderm (DE), Spheroids (Sph), and induced human intestinal organoids (iHIOs) from colitic and normal primary patient colon tissues
|
| |
|
| Overall design |
Transcriptome analysis of iPSCs, DE, Spheroids and iHIOs isolated from colitic and normal primary tissues.
|
| |
|
| Contributor(s) |
Huang E |
| Citation(s) |
33431859 |
| NIH grant(s) |
| Grant ID |
Grant title |
Affiliation |
Name |
| U01 CA214300 |
An organotypic model recapitulating colon cancer microenvironment and metastasis |
CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE - CWRU |
Emina HUI-NA Huang |
| R01 CA237304 |
The miR-20/c-Myc/E2F Regulatory Axis is Critical for the Tumor Promoting Activity of Inflammatory Fibroblasts in Colitis-Associated Cancer |
CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE - CWRU |
Emina HUI-NA Huang |
|
| |
| Submission date |
Jul 18, 2018 |
| Last update date |
Jan 12, 2021 |
| Contact name |
Emina Huang |
| E-mail(s) |
huange2@ccf.org
|
| Phone |
2163863265
|
| Organization name |
Lerner Research Institute/Cleveland Clinic
|
| Department |
Stem Cell
|
| Lab |
Huang Lab
|
| Street address |
9500 Euclid Ave
|
| City |
Cleveland |
| State/province |
OH |
| ZIP/Postal code |
44195 |
| Country |
USA |
| |
|
| Platforms (1) |
| GPL16791 |
Illumina HiSeq 2500 (Homo sapiens) |
|
| Samples (24)
|
|
| Relations |
| BioProject |
PRJNA481790 |
| SRA |
SRP154390 |
Less...
More...