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| Status |
Public on Dec 27, 2008 |
| Title |
Gene expression analysis in primary human renal tumors, categorized by VHL genotype and HIF-alpha expression |
| Organism |
Homo sapiens |
| Experiment type |
Expression profiling by array
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| Summary |
Human renal cell carcinomas (RCC) have differential expression of HIF-1alpha and HIF-2alpha, depending on VHL genotype and other events.
Here, we have divided a series of RCC samples for HIF-alpha expression and VHL genotype, in order to define differentially expressed genes
Keywords: Patient Sample Study
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| Overall design |
A total of 57 frozen RCC samples were stained for HIF-1alpha and HIF-2alpha, and genotyped for VHL. 5 VHL WT/HIF-negative, 8 VHL-deficient/HIF-1alpha+/HIF-2alpha+ and 8 VHL-deficient/HIF-2alpha+ tumors were selected for microarray
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| Contributor(s) |
Gordan JD, Lal P, Letrero R, Parekh KN, Oquendo CE, Greenberg RA, Flaherty KT, Rathmell WK, Simon MC, Nathanson KL |
| Citation(s) |
19061835, 20871783 |
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| Submission date |
Jun 26, 2008 |
| Last update date |
Aug 19, 2019 |
| Contact name |
Bradley Wubbenhorst |
| E-mail(s) |
bwubb@mail.med.upenn.edu
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| Phone |
215-898-0248
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| Organization name |
University of Pennsylvannia
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| Street address |
421 Curie Blvd
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| City |
Philadelphia |
| State/province |
PA |
| ZIP/Postal code |
19104 |
| Country |
USA |
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| Platforms (1) |
| GPL571 |
[HG-U133A_2] Affymetrix Human Genome U133A 2.0 Array |
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| Samples (21)
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| Relations |
| BioProject |
PRJNA105743 |
| Supplementary file |
Size |
Download |
File type/resource |
| GSE11904_RAW.tar |
36.9 Mb |
(http)(custom) |
TAR (of CEL) |
| Processed data included within Sample table |
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